Paper2555151

A transforming function of the BARF1 gene encoded by Epstein-Barr virus.

Wei MX and 1 other. EMBO J, 1989. Cited by 98 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

Cite this record

ConductScience Library. A transforming function of the BARF1 gene encoded by Epstein-Barr virus. Papers, record 2555151. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/2555151

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: A transforming function of the BARF1 gene encoded by Epstein-Barr virus.; PubMed
Journal: EMBO J; PubMed
Year: 1989; PubMed
Publication types: Journal Article, Research Support, Non-U.S. Gov't; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/2555151/; PubMed
DOI: https://doi.org/10.1002/j.1460-2075.1989.tb08438.x; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC401352/; PubMed
The journal: https://conductscience.org/library/journal-index/8208664; PubMed
Citations, by iCite: 98; iCite
Relative citation ratio, by iCite: 2.19; iCite
Revised in PubMed: 2022-05-11; PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Wei MX	M X
2	Ooka T	T

Source PubMed

Topics19

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Cell Transformation, Neoplastic	Major topic
Cell Transformation, Viral	Major topic
Genes, Viral	Major topic
Herpesvirus 4, Human	Major topic
Oncogenes	Major topic
Viral Proteins	Major topic
Animals
Cell Division
Cell Line, Transformed
Gene Expression
Humans
Immunoblotting
Kinetics
Mice
Mice, Inbred BALB C
Rats
Restriction Mapping
Transfection
Virus Replication

Source PubMed

Show 13 more topicsShow fewer topics

References26

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	3,027,378	Epstein-Barr virus glycoprotein homologous to herpes simplex virus gB.	J Virol	1987	https://conductscience.org/library/papers/3027378	PubMed
2	3,541,204	The molecular genetics of cancer.	Science	1987	https://conductscience.org/library/papers/3541204	PubMed
3	3,304,147	ras genes.	Annu Rev Biochem	1987	https://conductscience.org/library/papers/3304147	PubMed
4	2,822,969	The E6-E7 region of human papillomavirus type 18 is sufficient for transformation of NIH 3T3 and rat-1 cells.	J Virol	1987	https://conductscience.org/library/papers/2822969	PubMed
5	2,895,366	Role of epithelium in EBV persistence and pathogenesis of B-cell tumours.	Lancet	1988	https://conductscience.org/library/papers/2895366	PubMed
6	2,835,494	Altered expression of two Epstein-Barr virus early genes localized in BamHI-A in nonproducer Raji cells.	J Virol	1988	https://conductscience.org/library/papers/2835494	PubMed
7	2,836,780	Transformation of Balb 3T3 cells by the BNLF-1 gene of Epstein-Barr virus.	Oncogene	1988	https://conductscience.org/library/papers/2836780	PubMed
8	2,844,969	Ribonucleotide reductase encoded by herpes simplex virus is a determinant of the pathogenicity of the virus in mice and a valid antiviral target.	J Gen Virol	1988	https://conductscience.org/library/papers/2844969	PubMed
9	4,317,455	Aspects of the EB virus.	Adv Cancer Res	1970	https://conductscience.org/library/papers/4317455	PubMed
10	4,705,382	A new technique for the assay of infectivity of human adenovirus 5 DNA.	Virology	1973	https://conductscience.org/library/papers/4705382	PubMed
11	4,372,601	Differences between laboratory strains of Epstein-Barr virus based on immortalization, abortive infection, and interference.	Proc Natl Acad Sci U S A	1974	https://conductscience.org/library/papers/4372601	PubMed
12	179,207	Inhibition of productive replication of Epstein-Barr virus DNA by phosphonoacetic acid.	Virology	1976	https://conductscience.org/library/papers/179207	PubMed
13	219,209	Characterization of an Epstein-Barr virus-induced DNA polymerase.	J Virol	1979	https://conductscience.org/library/papers/219209	PubMed
14	286,319	DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells.	Proc Natl Acad Sci U S A	1979	https://conductscience.org/library/papers/286319	PubMed
15	6,249,024	Effects of arabinofuranosylthymine on Epstein-Barr virus replication.	Virology	1980	https://conductscience.org/library/papers/6249024	PubMed
16	6,286,831	Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter.	J Mol Appl Genet	1982	https://conductscience.org/library/papers/6286831	PubMed
17	6,308,472	Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes.	Nature	1983	https://conductscience.org/library/papers/6308472	PubMed
18	6,319,766	Epstein-Barr virus-specific DNase activity in nonproducer Raji cells after treatment with 12-o-tetradecanoylphorbol-13-acetate and sodium butyrate.	J Virol	1984	https://conductscience.org/library/papers/6319766	PubMed
19	6,325,929	Immortalization of monkey epithelial cells by specific fragments of Epstein-Barr virus DNA.	Nature	1984	https://conductscience.org/library/papers/6325929	PubMed
20	6,331,674	Construction and applications of a highly transmissible murine retrovirus shuttle vector.	Cell	1984	https://conductscience.org/library/papers/6331674	PubMed

Show 14 more referencesShow fewer referencesSee all 26 references

Cited by46

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 98 citations.

PMID	Title	Journal	Year	In Papers	Source
42,749,966	Functional contribution of Epstein-Barr virus BARF1 residues 35-39 to viable cell maintenance under serum deprivation and tumor formation.	Virus Genes	2026	https://conductscience.org/library/papers/42749966	PubMed
32,774,155	Co-presence of human papillomaviruses and Epstein-Barr virus is linked with advanced tumor stage: a tissue microarray study in head and neck cancer patients.	Cancer Cell Int	2020	https://conductscience.org/library/papers/32774155	PubMed
32,708,965	The Therapeutic Potential of Targeting BARF1 in EBV-Associated Malignancies.	Cancers (Basel)	2020	https://conductscience.org/library/papers/32708965	PubMed
30,769,835	The Phylogeographic Diversity of EBV and Admixed Ancestry in the Americas⁻Another Model of Disrupted Human-Pathogen Co-Evolution.	Cancers (Basel)	2019	https://conductscience.org/library/papers/30769835	PubMed
29,601,503	The Immunomodulatory Capacity of an Epstein-Barr Virus Abortive Lytic Cycle: Potential Contribution to Viral Tumorigenesis.	Cancers (Basel)	2018	https://conductscience.org/library/papers/29601503	PubMed
28,507,812	A BARF1-specific mAb as a new immunotherapeutic tool for the management of EBV-related tumors.	Oncoimmunology	2017	https://conductscience.org/library/papers/28507812	PubMed
28,487,730	The Methylation Status and Expression of Epstein-Barr Virus Early Genes BARF1 and BHRF1 in Epstein-Barr Virus-Associated Gastric Carcinomas.	Gastroenterol Res Pract	2017	https://conductscience.org/library/papers/28487730	PubMed
27,687,982	Epstein-Barr virus: more than 50 years old and still providing surprises.	Nat Rev Cancer	2016	https://conductscience.org/library/papers/27687982	PubMed
27,438,138	Epstein-Barr virus BARF1-induced NFκB/miR-146a/SMAD4 alterations in stomach cancer cells.	Oncotarget	2016	https://conductscience.org/library/papers/27438138	PubMed
26,038,756	Oncogenes and RNA splicing of human tumor viruses.	Emerg Microbes Infect	2014	https://conductscience.org/library/papers/26038756	PubMed
25,910,483	The role of Epstein-Barr virus infection in the pathogenesis of nasopharyngeal carcinoma.	Virol Sin	2015	https://conductscience.org/library/papers/25910483	PubMed
25,740,140	BARF1 gene silencing triggers caspase-dependent mitochondrial apoptosis in Epstein-Barr virus-positive malignant cells.	J Biosci	2015	https://conductscience.org/library/papers/25740140	PubMed
24,586,173	The Epstein-Barr virus-encoded microRNA MiR-BART9 promotes tumor metastasis by targeting E-cadherin in nasopharyngeal carcinoma.	PLoS Pathog	2014	https://conductscience.org/library/papers/24586173	PubMed
23,996,634	BamHI-A rightward frame 1, an Epstein-Barr virus-encoded oncogene and immune modulator.	Rev Med Virol	2013	https://conductscience.org/library/papers/23996634	PubMed
23,824,821	Epstein-Barr virus-encoded BARF1 promotes proliferation of gastric carcinoma cells through regulation of NF-κB.	J Virol	2013	https://conductscience.org/library/papers/23824821	PubMed
22,902,366	Allosteric competitive inactivation of hematopoietic CSF-1 signaling by the viral decoy receptor BARF1.	Nat Struct Mol Biol	2012	https://conductscience.org/library/papers/22902366	PubMed
22,826,234	Multipronged attenuation of macrophage-colony stimulating factor signaling by Epstein-Barr virus BARF1.	Proc Natl Acad Sci U S A	2012	https://conductscience.org/library/papers/22826234	PubMed
21,358,976	Recent Advances on the Possible Neuroprotective Activities of Epstein-Barr Virus Oncogene BARF1 Protein in Chronic Inflammatory Disorders of Central Nervous System.	Curr Neuropharmacol	2010	https://conductscience.org/library/papers/21358976	PubMed
21,152,115	Viral oncogenes, noncoding RNAs, and RNA splicing in human tumor viruses.	Int J Biol Sci	2010	https://conductscience.org/library/papers/21152115	PubMed
21,084,476	Cloning of the Epstein-Barr virus-related rhesus lymphocryptovirus as a bacterial artificial chromosome: a loss-of-function mutation of the rhBARF1 immune evasion gene.	J Virol	2011	https://conductscience.org/library/papers/21084476	PubMed

Show 14 more cited byShow fewer cited bySee all 46 cited by

Genes1

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes
ING1	3,621	PubTator's text mining	https://conductscience.org/library/genes/3621

Source NCBI Gene

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The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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ClinicalTrials.govNo license stated
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iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

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ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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