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Paper · 26549697

Plasma biomarker for detection of early stage pancreatic cancer and risk factors for pancreatic malignancy using antibodies for apolipoprotein-AII isoforms.

Honda K and 22 others. Sci Rep, 2015. Cited by 80 papers, by iCite.

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ConductScience Library. Plasma biomarker for detection of early stage pancreatic cancer and risk factors for pancreatic malignancy using antibodies for apolipoprotein-AII isoforms. Papers, record 26549697. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/26549697

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Plasma biomarker for detection of early stage pancreatic cancer and risk factors for pancreatic malignancy using antibodies for apolipoprotein-AII isoforms.
PubMed
Journal
Sci Rep
PubMed
Year
2015
PubMed
Publication types
Journal Article, Research Support, Non-U.S. Gov't
PubMed
Citations, by iCite
80
iCite
Relative citation ratio, by iCite
2.74
iCite
Revised in PubMed
2022-04-08
PubMed

Authors23

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Honda KKazufumi
2Kobayashi MMichimoto
3Okusaka TTakuji
4Rinaudo JAJo Ann
5Huang YYing
6Marsh TTracey
7Sanada MMitsuaki
8Sasajima YYoshiyuki
9Nakamori SShoji
10Shimahara MMasashi

1 to 10 of 23Source PubMed

See all 23 authors

Topics13

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Apolipoprotein A-IIMajor topic
Biomarkers, TumorMajor topic
Early Detection of CancerMajor topic
Pancreatic NeoplasmsMajor topic
Adult
Aged
Antibodies
Enzyme-Linked Immunosorbent Assay
Female
Humans
Male
Middle Aged
Risk Factors

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References24

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
111,459,866Phases of biomarker development for early detection of cancer.J Natl Cancer Inst2001https://conductscience.org/library/papers/11459866PubMed
223,248,327Proteomic approaches to the discovery of cancer biomarkers for early detection and personalized medicine.Jpn J Clin Oncol2013https://conductscience.org/library/papers/23248327PubMed
319,696,023Prolyl 4-hydroxylation of alpha-fibrinogen: a novel protein modification revealed by plasma proteomics.J Biol Chem2009https://conductscience.org/library/papers/19696023PubMed
417,097,848Systematic review of carbohydrate antigen (CA 19-9) as a biochemical marker in the diagnosis of pancreatic cancer.Eur J Surg Oncol2007https://conductscience.org/library/papers/17097848PubMed
524,574,362Copy number increase of ACTN4 is a prognostic indicator in salivary gland carcinoma.Cancer Med2014https://conductscience.org/library/papers/24574362PubMed
623,193,062The Early Detection Research Network's Specimen reference sets: paving the way for rapid evaluation of potential biomarkers.Clin Chem2013https://conductscience.org/library/papers/23193062PubMed
723,899,839Distinct outcome of stage I lung adenocarcinoma with ACTN4 cell motility gene amplification.Ann Oncol2013https://conductscience.org/library/papers/23899839PubMed
86,163,212Specific antigen in serum of patients with colon carcinoma.Science1981https://conductscience.org/library/papers/6163212PubMed
918,333,101Evaluation of pro-carboxypeptidase A and carboxypeptidase A as serologic markers for adenocarcinoma of the pancreas.HPB (Oxford)2006https://conductscience.org/library/papers/18333101PubMed
1023,056,525Altered plasma apolipoprotein modifications in patients with pancreatic cancer: protein characterization and multi-institutional validation.PLoS One2012https://conductscience.org/library/papers/23056525PubMed

Cited by63

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 80 citations.

PMIDTitleJournalYearIn PapersSource
42,824,914ApoA2 isoforms as blood-based biomarkers reflecting pancreatic exocrine dysfunction for risk stratification and perioperative management of pancreatic cancer.Front Oncol2026https://conductscience.org/library/papers/42824914PubMed
42,569,440Monitoring with plasma apolipoprotein A2-isoforms can predict developing new-onset steatotic liver disease caused by pancreatic exocrine insufficiency following pancreatectomy.Hepatobiliary Surg Nutr2026https://conductscience.org/library/papers/42569440PubMed
42,500,027Synthesis Based on Covalent Capture and Release Enables Purification-free Fluorogenic Probe Libraries for Single-Molecule Protease Activity Profiling.ACS Cent Sci2026https://conductscience.org/library/papers/42500027PubMed
41,976,399Comparison of Comprehensive Serum miRNA Sequencing and Apolipoprotein A2 Isoforms for Early Detection of Pancreatic Cancer.Cancers (Basel)2026https://conductscience.org/library/papers/41976399PubMed
41,767,619Clinical Utility of the Apolipoprotein A2 Isoform Index as a Tumor Marker for Pancreatic Cancer.JGH Open2026https://conductscience.org/library/papers/41767619PubMed
41,681,997Liquid Biopsy for Early Pancreatic Cancer Detection: Why Has It Not Yet Worked?Cancers (Basel)2026https://conductscience.org/library/papers/41681997PubMed
41,097,766Unusual Manifestations of Primary Pancreatic Neoplasia.Cancers (Basel)2025https://conductscience.org/library/papers/41097766PubMed
40,895,517High Score of ELST-Blue in Endoscopic Ultrasonography Strain Elastography May Provide a High Risk Group of Early Chronic Pancreatitis with the Reduction of Apolipoprotein A2-i Index.DEN Open2026https://conductscience.org/library/papers/40895517PubMed
40,363,817Early-Stage Pancreatic Cancer Diagnosis: Serum Biomarkers and the Potential for Aptamer-Based Biosensors.Molecules2025https://conductscience.org/library/papers/40363817PubMed
40,171,807From discovery to clinical implementation of a pancreatic blood biomarker, apolipoprotein A2 isoform.Cancer Biomark2025https://conductscience.org/library/papers/40171807PubMed

1 to 10 of 63

See all 63 cited by

Genes2

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
APOA2336PubTator's text mininghttps://conductscience.org/library/genes/336NCBI Gene
GSTK1373,156PubTator's text mininghttps://conductscience.org/library/genes/373156NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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