Paper · 268248

Model-building studies of antigen-binding sites: the hapten-binding site of mopc-315.

Padlan EA and 4 others. Cold Spring Harb Symp Quant Biol, 1977. Cited by 79 papers, by iCite.

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ConductScience Library. Model-building studies of antigen-binding sites: the hapten-binding site of mopc-315. Papers, record 268248. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/268248

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Model-building studies of antigen-binding sites: the hapten-binding site of mopc-315.; PubMed
Journal: Cold Spring Harb Symp Quant Biol; PubMed
Year: 1977; PubMed
Publication types: Journal Article, Research Support, U.S. Gov't, P.H.S.; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/268248/; PubMed
DOI: https://doi.org/10.1101/sqb.1977.041.01.072; PubMed
The journal: https://conductscience.org/library/journal-index/1256107; PubMed
Citations, by iCite: 79; iCite
Relative citation ratio, by iCite: 1.7; iCite
Revised in PubMed: 2019-08-23; PubMed

Authors5

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Padlan EA	E A
2	Davies DR	D R
3	Pecht I	I
4	Givol D	D
5	Wright C	C

Source PubMed

Topics13

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Binding Sites, Antibody	Major topic
Dinitrobenzenes	Major topic
Models, Molecular	Major topic
Models, Structural	Major topic
Myeloma Proteins	Major topic
Nitrobenzenes	Major topic
Amino Acid Sequence
Animals
Antibodies
Immunoglobulin Variable Region
Mice
Polysaccharides, Bacterial
Rabbits

Source PubMed

Grants0

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None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

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Cited by16

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 79 citations.

PMID	Title	Journal	Year	In Papers	Source
6,772,734	Evidence indicating independent assortment of framework and complementarity-determining segments of the variable regions of rabbit light chains. Delineation of a possible J minigene.	J Exp Med	1980	https://conductscience.org/library/papers/6772734	PubMed
6,435,124	Diversity at the variable-joining region boundary of lambda light chains has a pronounced effect on immunoglobulin ligand-binding activity.	Proc Natl Acad Sci U S A	1984	https://conductscience.org/library/papers/6435124	PubMed
6,417,753	Structural correlates of immunoglobulin diversity.	Surv Immunol Res	1983	https://conductscience.org/library/papers/6417753	PubMed
2,998,759	Members of novel VH gene families are found in VDJ regions of polyclonally activated B-lymphocytes.	EMBO J	1985	https://conductscience.org/library/papers/2998759	PubMed
2,457,920	Model-building study of the combining sites of two antibodies to alpha (1----6)dextran.	Proc Natl Acad Sci U S A	1988	https://conductscience.org/library/papers/2457920	PubMed
2,423,326	Modelling of the combining sites of three anti-lysozyme monoclonal antibodies and of the complex between one of the antibodies and its epitope.	EMBO J	1986	https://conductscience.org/library/papers/2423326	PubMed
2,410,256	Nucleotide sequences of five anti-lysozyme monoclonal antibodies.	EMBO J	1985	https://conductscience.org/library/papers/2410256	PubMed
2,410,255	Three distinct epitopes within the loop region of hen egg lysozyme defined with monoclonal antibodies.	EMBO J	1985	https://conductscience.org/library/papers/2410255	PubMed
1,281,216	Endogenous peptides of a soluble major histocompatibility complex class I molecule, H-2Lds: sequence motif, quantitative binding, and molecular modeling of the complex.	J Exp Med	1992	https://conductscience.org/library/papers/1281216	PubMed
743,221	Resonance Raman-spectroscopic studies of the hapten features involved in the binding of 2,4-dinitrophenyl haptens by the mouse myeloma proteins MOPC 315 and MOPC 460.	Biochem J	1978	https://conductscience.org/library/papers/743221	PubMed

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Genes0

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None in this release.

Drugs0

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None in this release.

Data0

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Data dates

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PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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