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Paper · 268647

Production of antibodies against influenza virus by somatic cell hybrids between mouse myeloma and primed spleen cells.

Koprowski H and 2 others. Proc Natl Acad Sci U S A, 1977. Cited by 182 papers, by iCite.

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ConductScience Library. Production of antibodies against influenza virus by somatic cell hybrids between mouse myeloma and primed spleen cells. Papers, record 268647. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/268647

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Production of antibodies against influenza virus by somatic cell hybrids between mouse myeloma and primed spleen cells.
PubMed
Journal
Proc Natl Acad Sci U S A
PubMed
Year
1977
PubMed
Publication types
Journal Article, Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
182
iCite
Relative citation ratio, by iCite
5.21
iCite
Revised in PubMed
2019-05-01
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Koprowski HH
2Gerhard WW
3Croce CMC M

Source PubMed

Topics13

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Antibodies, ViralMajor topic
Hybrid CellsMajor topic
Influenza A virusMajor topic
Animals
Antibody Specificity
Hemagglutinins, Viral
Immunoglobulin Allotypes
Immunoglobulin G
Karyotyping
Mice
Myeloma Proteins
Neoplasms, Experimental
Spleen

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References16

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
114,168,277SELECTION OF HYBRIDS FROM MATINGS OF FIBROBLASTS IN VITRO AND THEIR PRESUMED RECOMBINANTS.Science1964https://conductscience.org/library/papers/14168277PubMed
2193,032Persistence of virus-specific memory B cells in mice CNS.Nature1977https://conductscience.org/library/papers/193032PubMed
362,020The analysis of the monoclonal immune response to influenza virus. II. The antigenicity of the viral hemagglutinin.J Exp Med1976https://conductscience.org/library/papers/62020PubMed
4825,377Derivation of specific antibody-producing tissue culture and tumor lines by cell fusion.Eur J Immunol1976https://conductscience.org/library/papers/825377PubMed
51,028,164Improved techniques for the induction of mammalian cell hybridization by polyethylene glycol.Somatic Cell Genet1976https://conductscience.org/library/papers/1028164PubMed
61,242,069Production of mammalian somatic cell hybrids by means of polyethylene glycol treatment.Somatic Cell Genet1975https://conductscience.org/library/papers/1242069PubMed
74,349,247Comparison of direct and indirect solid-phase microradioimmunoassays for the detection of viral antigens and antiviral antibody.Appl Microbiol1973https://conductscience.org/library/papers/4349247PubMed
84,107,917A rapid banding technique for human chromosomes.Lancet1971https://conductscience.org/library/papers/4107917PubMed
94,361,084Unidirectional loss of human chromosomes in rat-human hybrids.Exp Cell Res1973https://conductscience.org/library/papers/4361084PubMed
104,102,405The stimulation of splenic foci in vitro.J Immunol1971https://conductscience.org/library/papers/4102405PubMed

1 to 10 of 16

See all 16 references

Cited by53

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 182 citations.

PMIDTitleJournalYearIn PapersSource
37,120,875Tyrosine-derived polymeric surfactant nanospheres insert cholesterol in cell membranes.J Colloid Interface Sci2023https://conductscience.org/library/papers/37120875PubMed
29,720,567Selection of phage-displayed accessible recombinant targeted antibodies (SPARTA): methodology and applications.JCI Insight2018https://conductscience.org/library/papers/29720567PubMed
10,484,291Immunoaffinity isolation of native membrane glucocorticoid receptor from S-49++ lymphoma cells: biochemical characterization and interaction with Hsp 70 and Hsp 90.Endocrine1999https://conductscience.org/library/papers/10484291PubMed
8,441,607Cloning, chromosomal localization and expression pattern of the POU domain gene Oct-11.Nucleic Acids Res1993https://conductscience.org/library/papers/8441607PubMed
8,005,673Partial characterization of a Candida albicans fimbrial adhesin.Infect Immun1994https://conductscience.org/library/papers/8005673PubMed
7,613,476Anti-peptide monoclonal antibody imaging of a common binding domain involved in muscle regulation.Protein Sci1995https://conductscience.org/library/papers/7613476PubMed
7,613,462Characterizing the microenvironment surrounding protein sites.Protein Sci1995https://conductscience.org/library/papers/7613462PubMed
7,459,230Somatic-cell hybrids producing antibodies against CEA.Br J Cancer1981https://conductscience.org/library/papers/7459230PubMed
7,288,173Frequency of naturally occurring antibody to influenza virus antigenic variants selected in vitro with monoclonal antibody.J Hyg (Lond)1981https://conductscience.org/library/papers/7288173PubMed
7,284,234Application of monoclonal antibodies to purified CEA in clinical radioimmunoassay of human serum.Br J Cancer1981https://conductscience.org/library/papers/7284234PubMed

1 to 10 of 53

See all 53 cited by

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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