Paper · 270684

Cloning specific segments of the mammalian genome: bacteriophage lambda containing mouse globin and surrounding gene sequences.

Tilghman SM and 8 others. Proc Natl Acad Sci U S A, 1977. Cited by 230 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

Cite this record

ConductScience Library. Cloning specific segments of the mammalian genome: bacteriophage lambda containing mouse globin and surrounding gene sequences. Papers, record 270684. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/270684

On this page

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Cloning specific segments of the mammalian genome: bacteriophage lambda containing mouse globin and surrounding gene sequences.; PubMed
Journal: Proc Natl Acad Sci U S A; PubMed
Year: 1977; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/270684/; PubMed
DOI: https://doi.org/10.1073/pnas.74.10.4406; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC431951/; PubMed
The journal: https://conductscience.org/library/journal-index/7505876; PubMed
Citations, by iCite: 230; iCite
Relative citation ratio, by iCite: 4.8; iCite
Revised in PubMed: 2019-05-01; PubMed

Authors9

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Tilghman SM	S M
2	Tiemeier DC	D C
3	Polsky F	F
4	Edgell MH	M H
5	Seidman JG	J G
6	Leder A	A
7	Enquist LW	L W
8	Norman B	B
9	Leder P	P

Source PubMed

Topics13

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Coliphages	Major topic
DNA, Recombinant	Major topic
Globins	Major topic
Animals
Base Sequence
Chromosome Mapping
DNA
DNA Replication
DNA Restriction Enzymes
Genes
Mice
Nucleic Acid Hybridization
Recombination, Genetic

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References28

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	13,955,956	Hemoglobin inheritance in inbred mouse strains. II. Genetic studies.	Proc Natl Acad Sci U S A	1962	https://conductscience.org/library/papers/13955956	PubMed
2	338,418	Cloning and amplification of alpha and beta mouse globin gene sequences synthesised in vitro.	Gene	1977	https://conductscience.org/library/papers/338418	PubMed
3	558,827	The primary structure of rabbit beta-globin mRNA as determined from cloned DNA.	Cell	1977	https://conductscience.org/library/papers/558827	PubMed
4	322,279	Screening lambdagt recombinant clones by hybridization to single plaques in situ.	Science	1977	https://conductscience.org/library/papers/322279	PubMed
5	786,462	Isolation of bacteriophage lambda containing yeast ribosomal RNA genes: screening by in situ RNA hybridization to plaques.	Cell	1976	https://conductscience.org/library/papers/786462	PubMed
6	1,067,476	Improved derivative of a phage lambda EK2 vector for cloning recombinant DNA.	Nature	1976	https://conductscience.org/library/papers/1067476	PubMed
7	1,067,607	Preparative fractionation of DNA restriction fragments by reversed phase column chromatography.	Proc Natl Acad Sci U S A	1976	https://conductscience.org/library/papers/1067607	PubMed
8	995,644	Preparative fractionation of DNA restriction fragments by high pressure column chromatography on RPC-5.	Nucleic Acids Res	1976	https://conductscience.org/library/papers/995644	PubMed
9	1,055,375	Nucleotide sequence of the rightward operator of phage lambda.	Proc Natl Acad Sci U S A	1975	https://conductscience.org/library/papers/1055375	PubMed
10	4,638,756	A comparison of globin genes in duck reticulocytes and liver cells.	Biochem Biophys Res Commun	1972	https://conductscience.org/library/papers/4638756	PubMed

1 to 10 of 28

See all 28 references

Cited by72

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 230 citations.

PMID	Title	Journal	Year	In Papers	Source
32,907,976	Biographical Feature: The Long and Winding Road: My Career Path and How I Ended Up Where I Am Now.	J Virol	2020	https://conductscience.org/library/papers/32907976	PubMed
17,322,350	The 2007 Genetics Society of America Medal. Shirley Tilghman.	Genetics	2007	https://conductscience.org/library/papers/17322350	PubMed
8,290,590	Mice lacking N-acetylglucosaminyltransferase I activity die at mid-gestation, revealing an essential role for complex or hybrid N-linked carbohydrates.	Proc Natl Acad Sci U S A	1994	https://conductscience.org/library/papers/8290590	PubMed
7,638,196	WW6: an embryonic stem cell line with an inert genetic marker that can be traced in chimeras.	Proc Natl Acad Sci U S A	1995	https://conductscience.org/library/papers/7638196	PubMed
7,045,395	Demonstration of biological activity and nucleotide sequence of an in vitro synthesized clone of the Moloney murine sarcoma virus mos gene.	J Virol	1982	https://conductscience.org/library/papers/7045395	PubMed
6,952,215	Specific differentiation events induced by erythropoietin in cells infected in vitro with the anemia strain of Friend virus.	Proc Natl Acad Sci U S A	1982	https://conductscience.org/library/papers/6952215	PubMed
6,941,285	Mouse beta-globin and adenovirus-2 major late transcripts are initiated at the cap site in vitro.	Proc Natl Acad Sci U S A	1981	https://conductscience.org/library/papers/6941285	PubMed
6,941,279	Nuclear ribonucleoprotein particles probed in living cells.	Proc Natl Acad Sci U S A	1981	https://conductscience.org/library/papers/6941279	PubMed
6,932,401	Messenger RNA processing and nuclear structure: isolation of nuclear ribonucleoprotein particles containing beta-globin messenger RNA precursors.	J Cell Biol	1980	https://conductscience.org/library/papers/6932401	PubMed
6,777,777	Immunoglobulin V/J recombination is accompanied by deletion of joining site and variable region segments.	Proc Natl Acad Sci U S A	1980	https://conductscience.org/library/papers/6777777	PubMed

1 to 10 of 72

See all 72 cited by

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this paper from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/papers/v1/270684

GET https://conductscience.org/api/papers/v1/270684/references?page=2

API reference For AI assistants