Paper · 27681908

Bacterial Multidrug Efflux Pumps: Much More Than Antibiotic Resistance Determinants.

Blanco P and 8 others. Microorganisms, 2016. Cited by 452 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Bacterial Multidrug Efflux Pumps: Much More Than Antibiotic Resistance Determinants. Papers, record 27681908. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/27681908

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Bacterial Multidrug Efflux Pumps: Much More Than Antibiotic Resistance Determinants.; PubMed
Journal: Microorganisms; PubMed
Year: 2016; PubMed
Publication types: Journal Article, Review; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/27681908/; PubMed
DOI: https://doi.org/10.3390/microorganisms4010014; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC5029519/; PubMed
The journal: https://conductscience.org/library/journal-index/101625893; PubMed
Citations, by iCite: 452; iCite
Relative citation ratio, by iCite: 21.1; iCite
Revised in PubMed: 2022-04-08; PubMed

Authors9

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Blanco P	Paula
2	Hernando-Amado S	Sara
3	Reales-Calderon JA	Jose Antonio
4	Corona F	Fernando
5	Lira F	Felipe
6	Alcalde-Rico M	Manuel
7	Bernardini A	Alejandra
8	Sanchez MB	Maria Blanca
9	Martinez JL	Jose Luis

Source PubMed

Topics0

NLM's MeSH indexing of the paper, its major topics first.

None in this release.

Grants1

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes it	Agency	Country	NIH project	Stated by
L60 MD002414	NIMHD NIH HHS	United States	L60MD002414	PubMed and NIH

Source NIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References160

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	8,521,301	The MarR repressor of the multiple antibiotic resistance (mar) operon in Escherichia coli: prototypic member of a family of bacterial regulatory proteins involved in sensing phenolic compounds.	Mol Med	1995	https://conductscience.org/library/papers/8521301	PubMed
2	13,129,948	Erwinia chrysanthemi tolC is involved in resistance to antimicrobial plant chemicals and is essential for phytopathogenesis.	J Bacteriol	2003	https://conductscience.org/library/papers/13129948	PubMed
3	11,378,963	SMR-type multidrug resistance pumps.	Curr Opin Drug Discov Devel	2001	https://conductscience.org/library/papers/11378963	PubMed
4	24,176,982	Inhibition of multidrug efflux as a strategy to prevent biofilm formation.	J Antimicrob Chemother	2014	https://conductscience.org/library/papers/24176982	PubMed
5	7,651,136	Genes acrA and acrB encode a stress-induced efflux system of Escherichia coli.	Mol Microbiol	1995	https://conductscience.org/library/papers/7651136	PubMed
6	17,784,941	Genomic analysis reveals the major driving forces of bacterial life in the rhizosphere.	Genome Biol	2007	https://conductscience.org/library/papers/17784941	PubMed
7	15,687,203	Overexpression of the multidrug efflux pumps MexCD-OprJ and MexEF-OprN is associated with a reduction of type III secretion in Pseudomonas aeruginosa.	J Bacteriol	2005	https://conductscience.org/library/papers/15687203	PubMed
8	12,481,830	Active efflux, a common mechanism for biocide and antibiotic resistance.	Symp Ser Soc Appl Microbiol	2002	https://conductscience.org/library/papers/12481830	PubMed
9	12,069,964	CmeABC functions as a multidrug efflux system in Campylobacter jejuni.	Antimicrob Agents Chemother	2002	https://conductscience.org/library/papers/12069964	PubMed
10	8,821,940	The local repressor AcrR plays a modulating role in the regulation of acrAB genes of Escherichia coli by global stress signals.	Mol Microbiol	1996	https://conductscience.org/library/papers/8821940	PubMed

1 to 10 of 160

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Cited by295

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 452 citations.

PMID	Title	Journal	Year	In Papers	Source
42,959,485	Mechanistic insights into the synergistic interactions between macrolides and beta-lactams in bacterial infections.	Front Cell Infect Microbiol	2026	https://conductscience.org/library/papers/42959485	PubMed
42,953,619	Addition of Chinese medicinal herbal residues promotes the removal of antibiotic resistance genes during pig manure composting.	Front Microbiol	2026	https://conductscience.org/library/papers/42953619	PubMed
42,934,726	The resistome of European coastal environments revealed by high-resolution targeted metagenomics in oysters.	Microbiome	2026	https://conductscience.org/library/papers/42934726	PubMed
42,909,663	Prospecting for efflux pump and repressor genes in rivers of the Amazon region of Brazil.	Mol Biol Rep	2026	https://conductscience.org/library/papers/42909663	PubMed
42,883,703	Gut Microbiota Signatures Associated with Metastatic Prostatic Cancer Treated with Androgen Receptor Pathway Inhibitor (ARPI) Therapy.	Int J Mol Sci	2026	https://conductscience.org/library/papers/42883703	PubMed
42,643,414	Wastewater treatment plant effluent alters particle-associated bacterial assemblages in an intermittent stream.	Front Microbiol	2026	https://conductscience.org/library/papers/42643414	PubMed
42,579,328	Microbial interactions as key players shaping the emergence and spread of de novo resistance mutations.	Microbiology (Reading)	2026	https://conductscience.org/library/papers/42579328	PubMed
42,560,587	Radiation-resistant and desiccation-tolerant bacteria from the Chavara-Neendakara high background radiation area, india: phenotypic characterisation and genomic insights.	Antonie Van Leeuwenhoek	2026	https://conductscience.org/library/papers/42560587	PubMed
42,551,477	Antimicrobial Resistance of Serratia marcescens Recovered From Aquatic Environments: A Review.	Environ Microbiol Rep	2026	https://conductscience.org/library/papers/42551477	PubMed
42,536,690	Schisandrins as novel efflux pumps inhibitors and non-antibiotic compounds against multi- and extensively-drug resistant clinical strains of Salmonella typhi: An in-vitro study.	PLoS One	2026	https://conductscience.org/library/papers/42536690	PubMed

1 to 10 of 295

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Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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