Paper2822019

Role of fructose 2,6-bisphosphate in the control of glycolysis in mammalian tissues.

Hue L and 1 other. Biochem J, 1987. Cited by 366 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Role of fructose 2,6-bisphosphate in the control of glycolysis in mammalian tissues. Papers, record 2822019. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/2822019

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Role of fructose 2,6-bisphosphate in the control of glycolysis in mammalian tissues.; PubMed
Journal: Biochem J; PubMed
Year: 1987; PubMed
Publication types: Journal Article, Research Support, Non-U.S. Gov't, Review; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/2822019/; PubMed
DOI: https://doi.org/10.1042/bj2450313; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC1148124/; PubMed
The journal: https://conductscience.org/library/journal-index/2984726R; PubMed
Citations, by iCite: 366; iCite
Relative citation ratio, by iCite: 8.76; iCite
Revised in PubMed: 2019-05-01; PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Hue L	L
2	Rider MH	M H

Source PubMed

Topics10

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Fructosediphosphates	Major topic
Glycolysis	Major topic
Hexosediphosphates	Major topic
Mammals	Major topic
Animals
Liver
Phosphofructokinase-2
Phosphoric Monoester Hydrolases
Phosphorylation
Tissue Distribution

Source PubMed

Show 4 more topicsShow fewer topics

References166

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	6,688,419	The interaction of fructose 2,6-bisphosphate and AMP with rat hepatic fructose 1,6-bisphosphatase.	J Biol Chem	1983	https://conductscience.org/library/papers/6688419	PubMed
2	6,260,770	Inhibition of fructose-1,6-bisphosphatase by fructose 2,6-bisphosphate.	J Biol Chem	1981	https://conductscience.org/library/papers/6260770	PubMed
3	6,453,589	Fructose 2,6-bisphosphate, the probably structure of the glucose- and glucagon-sensitive stimulator of phosphofructokinase.	Biochem J	1980	https://conductscience.org/library/papers/6453589	PubMed
4	319,362	Enzymology of cancer cells (first of two parts).	N Engl J Med	1977	https://conductscience.org/library/papers/319362	PubMed
5	3,021,137	Effect of tolbutamide on fructose-6-phosphate,2-kinase and fructose-2,6-bisphosphatase in rat liver.	Biochem Biophys Res Commun	1986	https://conductscience.org/library/papers/3021137	PubMed
6	6,092,364	Effect of sulfhydryl modification on the activities of rat liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.	J Biol Chem	1984	https://conductscience.org/library/papers/6092364	PubMed
7	2,997,199	Fructose-1,6-bisphosphatase from rat liver. A comparison of the kinetics of the unphosphorylated enzyme and the enzyme phosphorylated by cyclic AMP-dependent protein kinase.	J Biol Chem	1985	https://conductscience.org/library/papers/2997199	PubMed
8	4,830,198	A linear steady-state treatment of enzymatic chains. General properties, control and effector strength.	Eur J Biochem	1974	https://conductscience.org/library/papers/4830198	PubMed
9	6,392,338	The glucose paradox. Is glucose a substrate for liver metabolism?	J Clin Invest	1984	https://conductscience.org/library/papers/6392338	PubMed
10	3,010,981	Effects of diabetes on fructose 2, 6-P2, glucose 1, 6-P2 and 6-phosphofructo 2-kinase in rat liver.	Biochem Biophys Res Commun	1986	https://conductscience.org/library/papers/3010981	PubMed
11	6,096,384	Rat liver 6-phosphofructo 2-kinase/fructose 2,6-bisphosphatase: a review of relationships between the two activities of the enzyme.	J Cell Biochem	1984	https://conductscience.org/library/papers/6096384	PubMed
12	6,311,081	Gluconeogenesis and related aspects of glycolysis.	Annu Rev Biochem	1983	https://conductscience.org/library/papers/6311081	PubMed
13	6,453,588	Control of the fructose-6-phosphate/fructose 1,6-bisphosphate cycle in isolated hepatocytes by glucose and glucagon. Role of a low-molecular-weight stimulator of phosphofructokinase.	Biochem J	1980	https://conductscience.org/library/papers/6453588	PubMed
14	153,704	Phosphofructokinase.	Adv Enzymol Relat Areas Mol Biol	1979	https://conductscience.org/library/papers/153704	PubMed
15	6,092,081	The protein phosphatases involved in cellular regulation. Glycolysis, gluconeogenesis and aromatic amino acid breakdown in rat liver.	Eur J Biochem	1984	https://conductscience.org/library/papers/6092081	PubMed
16	6,301,824	The protein phosphatases involved in cellular regulation. 1. Classification and substrate specificities.	Eur J Biochem	1983	https://conductscience.org/library/papers/6301824	PubMed
17	3,004,827	Fructose 2,6-bisphosphate and enzymatic activities for its metabolism in ascites tumor.	Curr Top Cell Regul	1985	https://conductscience.org/library/papers/3004827	PubMed
18	6,688,179	Perinatal changes of fructose 2,6-bisphosphate in the rat liver.	Biochem Biophys Res Commun	1983	https://conductscience.org/library/papers/6688179	PubMed
19	3,019,688	Purification and properties of phosphofructokinase 2/fructose 2,6-bisphosphatase from chicken liver and from pigeon muscle.	Eur J Biochem	1986	https://conductscience.org/library/papers/3019688	PubMed
20	6,451,625	Fructose 2,6-bisphosphate. A new activator of phosphofructokinase.	J Biol Chem	1981	https://conductscience.org/library/papers/6451625	PubMed

Show 14 more referencesShow fewer referencesSee all 166 references

Cited by104

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 366 citations.

PMID	Title	Journal	Year	In Papers	Source
42,751,120	Metabolic reprogramming in colorectal cancer: Mechanisms and therapeutic insights.	Genes Dis	2027	https://conductscience.org/library/papers/42751120	PubMed
40,454,774	Neural Metabolic Networks: Key Elements of Healthy Brain Function.	J Neurochem	2025	https://conductscience.org/library/papers/40454774	PubMed
39,318,551	Pathogenic role of PFKFB3 in endothelial inflammatory diseases.	Front Mol Biosci	2024	https://conductscience.org/library/papers/39318551	PubMed
38,964,783	Genetically engineering glycolysis in T cells increases their antitumor function.	J Immunother Cancer	2024	https://conductscience.org/library/papers/38964783	PubMed
38,206,915	Ameliorating the impairment of glucose utilization in a high-fat diet-induced obesity model through the consumption of Tucum-do-Cerrado (Bactris Setosa Mart.).	PLoS One	2024	https://conductscience.org/library/papers/38206915	PubMed
37,958,470	PI3K/Akt/mTOR Signaling Pathway in Blood Malignancies-New Therapeutic Possibilities.	Cancers (Basel)	2023	https://conductscience.org/library/papers/37958470	PubMed
37,534,142	Increased cardiac PFK-2 protects against high-fat diet-induced cardiomyopathy and mediates beneficial systemic metabolic effects.	iScience	2023	https://conductscience.org/library/papers/37534142	PubMed
36,712,976	Immunometabolic factors contributing to obesity-linked hepatocellular carcinoma.	Front Cell Dev Biol	2022	https://conductscience.org/library/papers/36712976	PubMed
36,625,925	Autologous blood transfusion impedes glycolysis in macrophages to inhibit red blood cell injury in type 2 diabetes through PI3K/Akt/PKM2 signaling axis.	Acta Diabetol	2023	https://conductscience.org/library/papers/36625925	PubMed
35,879,299	Beyond controlling cell size: functional analyses of S6K in tumorigenesis.	Cell Death Dis	2022	https://conductscience.org/library/papers/35879299	PubMed
35,289,743	Octopamine drives honeybee thermogenesis.	Elife	2022	https://conductscience.org/library/papers/35289743	PubMed
35,140,684	Identification of Key LncRNAs and Pathways in Prediabetes and Type 2 Diabetes Mellitus for Hypertriglyceridemia Patients Based on Weighted Gene Co-Expression Network Analysis.	Front Endocrinol (Lausanne)	2021	https://conductscience.org/library/papers/35140684	PubMed
35,056,904	Current Status of the Use of Multifunctional Enzymes as Anti-Cancer Drug Targets.	Pharmaceutics	2021	https://conductscience.org/library/papers/35056904	PubMed
33,673,114	Cardiometabolism as an Interlocking Puzzle between the Healthy and Diseased Heart: New Frontiers in Therapeutic Applications.	J Clin Med	2021	https://conductscience.org/library/papers/33673114	PubMed
32,911,833	Signalling, Metabolic Pathways and Iron Homeostasis in Endothelial Cells in Health, Atherosclerosis and Alzheimer's Disease.	Cells	2020	https://conductscience.org/library/papers/32911833	PubMed
31,991,105	Metabolic Control over mTOR-Dependent Diapause-like State.	Dev Cell	2020	https://conductscience.org/library/papers/31991105	PubMed
31,686,003	The PI3K-AKT network at the interface of oncogenic signalling and cancer metabolism.	Nat Rev Cancer	2020	https://conductscience.org/library/papers/31686003	PubMed
31,413,316	Autophagy inhibition elicits emergence from metastatic dormancy by inducing and stabilizing Pfkfb3 expression.	Nat Commun	2019	https://conductscience.org/library/papers/31413316	PubMed
31,308,477	Inferring novel genes related to colorectal cancer via random walk with restart algorithm.	Gene Ther	2019	https://conductscience.org/library/papers/31308477	PubMed
31,185,774	Glucose Metabolism in Cardiac Hypertrophy and Heart Failure.	J Am Heart Assoc	2019	https://conductscience.org/library/papers/31185774	PubMed

Show 14 more cited byShow fewer cited bySee all 104 cited by

Data dates

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PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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PMC's ID filePublic domain (US government)
PubMedNLM's terms
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UniProtCC BY 4.0

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