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Paper · 2880852

Evidence for medetomidine as a selective and potent agonist at alpha 2-adrenoreceptors.

Savola JM and 4 others. J Auton Pharmacol, 1986. Cited by 103 papers, by iCite.

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ConductScience Library. Evidence for medetomidine as a selective and potent agonist at alpha 2-adrenoreceptors. Papers, record 2880852. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/2880852

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Evidence for medetomidine as a selective and potent agonist at alpha 2-adrenoreceptors.
PubMed
Journal
J Auton Pharmacol
PubMed
Year
1986
PubMed
Publication types
Comparative Study, Journal Article
PubMed
Citations, by iCite
103
iCite
Relative citation ratio, by iCite
5.71
iCite
Revised in PubMed
2019-10-29
PubMed

Authors5

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Savola JMJ M
2Ruskoaho HH
3Puurunen JJ
4Salonen JSJ S
5Kärki NTN T

Source PubMed

Topics15

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Adrenergic alpha-AgonistsMajor topic
ImidazolesMajor topic
Animals
Antihypertensive Agents
Aorta
Blood Pressure
Decerebrate State
Heart Rate
Male
Medetomidine
Posture
Rats
Rats, Inbred Strains
Reflex
Sympathetic Nervous System

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by33

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 103 citations.

PMIDTitleJournalYearIn PapersSource
40,721,375Comparative evaluation of anesthetic effects of medetomidine-midazolam-butorphanol and medetomidine-remimazolam-butorphanol administered subcutaneously and intraperitoneally in C57BL/6J mice.J Vet Med Sci2025https://conductscience.org/library/papers/40721375PubMed
39,405,508Classics in Chemical Neuroscience: Medetomidine.ACS Chem Neurosci2024https://conductscience.org/library/papers/39405508PubMed
36,185,505Effects of intranasal and intramuscular dexmedetomidine in cats receiving total intravenous propofol anesthesia.Vet World2022https://conductscience.org/library/papers/36185505PubMed
35,891,845Comparison of Fentanyl and Dexmedetomidine in Preventing an Increase in Heart Rate During Intubation Among Patients Undergoing General Anesthesia: A Meta-Analysis.Cureus2022https://conductscience.org/library/papers/35891845PubMed
35,452,606General anesthesia globally synchronizes activity selectively in layer 5 cortical pyramidal neurons.Neuron2022https://conductscience.org/library/papers/35452606PubMed
35,341,088Clinical Efficacy of Dexmedetomidine versus Ketamine in Shoulder Dislocation Reduction: A Randomized Clinical Trial Study.Med J Islam Repub Iran2021https://conductscience.org/library/papers/35341088PubMed
34,912,607Acute Colonic Pseudo-Obstruction Following the Use of Dexmedetomidine.Cureus2021https://conductscience.org/library/papers/34912607PubMed
31,222,586Comparing the effect of dexmedetomidine and labetalol on hemodynamic variables in patients undergoing microlaryngoscopy.Eur Arch Otorhinolaryngol2019https://conductscience.org/library/papers/31222586PubMed
30,559,858A Comparison of the Effects of Dexmedetomidine and Propofol in Controlling the Hemodynamic Responses after Intubation: A Double-Blind, Randomized, Clinical Trial Study.Open Access Maced J Med Sci2018https://conductscience.org/library/papers/30559858PubMed
28,571,235Effect of Dexmedetomidine Versus Fentanyl on Haemodynamic Response to Patients Undergoing Elective Laparoscopic Surgery: A Double Blinded Randomized Controlled Study.J Clin Diagn Res2017https://conductscience.org/library/papers/28571235PubMed

1 to 10 of 33

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Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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