Paper · 29201643

Relationships between brain metabolite levels, functional connectivity, and negative mood in urologic chronic pelvic pain syndrome patients compared to controls: A MAPP research network study.

Harper DE and 8 others. Neuroimage Clin, 2018. Cited by 44 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Relationships between brain metabolite levels, functional connectivity, and negative mood in urologic chronic pelvic pain syndrome patients compared to controls: A MAPP research network study. Papers, record 29201643. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/29201643

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Relationships between brain metabolite levels, functional connectivity, and negative mood in urologic chronic pelvic pain syndrome patients compared to controls: A MAPP research network study.; PubMed
Journal: Neuroimage Clin; PubMed
Year: 2018; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/29201643/; PubMed
DOI: https://doi.org/10.1016/j.nicl.2017.11.014; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC5702874/; PubMed
The journal: https://conductscience.org/library/journal-index/101597070; PubMed
Citations, by iCite: 44; iCite
Relative citation ratio, by iCite: 2.29; iCite
Revised in PubMed: 2022-03-21; PubMed

Authors9

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind
1	Harper DE	Daniel E
2	Ichesco E	Eric
3	Schrepf A	Andrew
4	Halvorson M	Megan
5	Puiu T	Tudor
6	Clauw DJ	Daniel J
7	Harris RE	Richard E
8	Harte SE	Steven E
9	MAPP Research Network		Group

Source PubMed

Topics15

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Brain	Major topic
Choline	Major topic
Pelvic Pain	Major topic
gamma-Aminobutyric Acid	Major topic
Adult
Chronic Pain
Cross-Sectional Studies
Emotions
Female
Humans
Image Interpretation, Computer-Assisted
Middle Aged
Proton Magnetic Resonance Spectroscopy
Syndrome
Young Adult

Source PubMed

Grants6

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes it	Agency	Country	NIH project	Stated by	Source
U01 DK082345	NIDDK NIH HHS	United States	U01DK082345	PubMed and NIH	NIH RePORTER
U01 DK082316	NIDDK NIH HHS	United States	U01DK082316	PubMed and NIH	NIH RePORTER
U24 DK082316	NIDDK NIH HHS	United States	U01DK082316	PubMed and NIH	NIH RePORTER
K99 DE026810	NIDCR NIH HHS	United States	K99DE026810	PubMed and NIH	NIH RePORTER
K12 DE023574	NIDCR NIH HHS	United States	K12DE023574	PubMed and NIH	NIH RePORTER
			U24DK082316	NIH	NIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References75

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	25,316,627	Women with dysmenorrhoea are hypersensitive to experimentally induced forearm ischaemia during painful menstruation and during the pain-free follicular phase.	Eur J Pain	2015	https://conductscience.org/library/papers/25316627	PubMed
2	3,397,865	Development and validation of brief measures of positive and negative affect: the PANAS scales.	J Pers Soc Psychol	1988	https://conductscience.org/library/papers/3397865	PubMed
3	3,670,870	The short-form McGill Pain Questionnaire.	Pain	1987	https://conductscience.org/library/papers/3670870	PubMed
4	24,343,290	Pregabalin rectifies aberrant brain chemistry, connectivity, and functional response in chronic pain patients.	Anesthesiology	2013	https://conductscience.org/library/papers/24343290	PubMed
5	25,711,200	Brain White Matter Abnormalities in Female Interstitial Cystitis/Bladder Pain Syndrome: A MAPP Network Neuroimaging Study.	J Urol	2015	https://conductscience.org/library/papers/25711200	PubMed
6	20,609,227	Localized 1H-NMR spectroscopy in patients with fibromyalgia: a controlled study of changes in cerebral glutamate/glutamine, inositol, choline, and N-acetylaspartate.	Arthritis Res Ther	2010	https://conductscience.org/library/papers/20609227	PubMed
7	21,913,179	Reduced insular γ-aminobutyric acid in fibromyalgia.	Arthritis Rheum	2012	https://conductscience.org/library/papers/21913179	PubMed
8	16,217,302	Menstrual cycle affects bladder pain sensation in subjects with interstitial cystitis.	J Urol	2005	https://conductscience.org/library/papers/16217302	PubMed
9	21,799,042	Metabolic abnormalities in pain-processing regions of patients with fibromyalgia: a 3T MR spectroscopy study.	AJNR Am J Neuroradiol	2011	https://conductscience.org/library/papers/21799042	PubMed
10	26,106,574	Altered resting state neuromotor connectivity in men with chronic prostatitis/chronic pelvic pain syndrome: A MAPP: Research Network Neuroimaging Study.	Neuroimage Clin	2015	https://conductscience.org/library/papers/26106574	PubMed

1 to 10 of 75

See all 75 references

Cited by32

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 44 citations.

PMID	Title	Journal	Year	In Papers	Source
42,824,364	Nanoparticle-based therapeutic platforms for inflammatory disorders of the urinary system: Engineering local delivery, biointerface regulation, and smart responsive therapy.	Mater Today Bio	2026	https://conductscience.org/library/papers/42824364	PubMed
42,782,815	Bladder Sensory Neurons as Regulators of Neuro-Immune-Urothelial Interactions: From Molecular Mechanisms to Targeted Therapy for Neurogenic Bladder and Interstitial Cystitis/Bladder Pain Syndrome.	Cells	2026	https://conductscience.org/library/papers/42782815	PubMed
42,271,120	Chronic Ocular Surface Pain: A Missing Member of the Chronic Overlapping Pain Conditions?	Drugs	2026	https://conductscience.org/library/papers/42271120	PubMed
42,022,492	Mechanistic Insights into Acupuncture for Chronic Prostatitis/Chronic Pelvic Pain Syndrome via Integrated Network Topology and Bioinformatics Analysis.	J Pain Res	2026	https://conductscience.org/library/papers/42022492	PubMed
39,615,812	Elevated posterior insula glutamate in patients with sickle cell disease.	J Pain	2025	https://conductscience.org/library/papers/39615812	PubMed
39,432,808	Brain predicted age in chronic pelvic pain: a study by the Multidisciplinary Approach to the Study of Chronic Pelvic Pain Research Network.	Pain	2025	https://conductscience.org/library/papers/39432808	PubMed
38,984,334	This pain drives me crazy: Psychiatric symptoms in women with interstitial cystitis/bladder pain syndrome.	World J Psychiatry	2024	https://conductscience.org/library/papers/38984334	PubMed
38,755,449	Deciphering nociplastic pain: clinical features, risk factors and potential mechanisms.	Nat Rev Neurol	2024	https://conductscience.org/library/papers/38755449	PubMed
37,626,838	Sexual Dimorphism in the Mechanism of Pain Central Sensitization.	Cells	2023	https://conductscience.org/library/papers/37626838	PubMed
37,510,853	Implicit Motor Imagery for Chronic Pelvic Pain: A Cross-Sectional Case-Control Study.	J Clin Med	2023	https://conductscience.org/library/papers/37510853	PubMed

1 to 10 of 32

See all 32 cited by

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

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ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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