ConductScience.org, home
Papers
API referenceFor AI assistants

Paper301145

Modulatory effects on immunoglobulin synthesis and secretion by lymphocytes from immunodeficient patients.

Schwartz SA and 3 others. J Clin Invest, 1977. Cited by 63 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

Download JSON
Cite this record

ConductScience Library. Modulatory effects on immunoglobulin synthesis and secretion by lymphocytes from immunodeficient patients. Papers, record 301145. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/301145

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Modulatory effects on immunoglobulin synthesis and secretion by lymphocytes from immunodeficient patients.
PubMed
Journal
J Clin Invest
PubMed
Year
1977
PubMed
Publication types
Journal Article, Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
63
iCite
Relative citation ratio, by iCite
1.96
iCite
Revised in PubMed
2018-11-30
PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Schwartz SAS A
2Choi YSY S
3Shou LL
4Good RAR A

Source PubMed

Topics20

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
ImmunoglobulinsMajor topic
Immunologic Deficiency SyndromesMajor topic
LymphocytesMajor topic
Adolescent
Adult
Agammaglobulinemia
B-Lymphocytes
Cell Differentiation
Cells, Cultured
Child
Child, Preschool
Female
Humans
Lectins
Male
Middle Aged
Sex Chromosomes
T-Lymphocytes
Thymoma
Thymus Neoplasms

Source PubMed

References21

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
3833,427Serological precipitation method for studying biosynthesis and secretion of immunoglobulins by human peripheral blood lymphocytes.J Immunol Methods1977https://conductscience.org/library/papers/833427PubMed
44,137,918Role of suppressor T cells in pathogenesis of common variable hypogammaglobulinaemia.Lancet1974https://conductscience.org/library/papers/4137918PubMed
54,179,068Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.Scand J Clin Lab Invest Suppl1968https://conductscience.org/library/papers/4179068PubMed
64,106,608Agammaglobulinaemia with B lymphocytes. Specific defect of plasma-cell differentiation.Lancet1971https://conductscience.org/library/papers/4106608PubMed
74,102,352Primary immunodeficiencies. Report of a World Health Organization Committee.Pediatrics1971https://conductscience.org/library/papers/4102352PubMed
8125,290Hodgkin's disease. An immunodepleting and immunosuppressive disorder.J Clin Invest1975https://conductscience.org/library/papers/125290PubMed
94,610,075Infectious agammaglobulinemia: transmission of immunodeficiency with grafts of agammaglobulinemic cells.J Exp Med1974https://conductscience.org/library/papers/4610075PubMed
1058,934Induction of specific suppressor T cells in vitro.J Immunol1976https://conductscience.org/library/papers/58934PubMed
113,737Correction of severe combined immunodeficiency by fetal liver cells.N Engl J Med1976https://conductscience.org/library/papers/3737PubMed
124,543,023Differentiation capacity of cultured B lymphocytes from immunodeficient patients.J Clin Invest1973https://conductscience.org/library/papers/4543023PubMed
134,545,549Heterogeneity of "acquired" or common variable agammaglobulinemia.N Engl J Med1974https://conductscience.org/library/papers/4545549PubMed
144,540,338Classification of primary immunodeficiencies.N Engl J Med1973https://conductscience.org/library/papers/4540338PubMed
15131,175Suppressor cell activity after concanavalin A treatment of lymphocytes from normal donors.J Exp Med1976https://conductscience.org/library/papers/131175PubMed
165,022,177Development of chicken lymphoid system. I. Synthesis and secretion of immunoglobulins by chicken lymphoid cells.J Exp Med1972https://conductscience.org/library/papers/5022177PubMed
174,999,540Immunoglobulins on the surface of lymphocytes. IV. Distribution in hypogammaglobulinemia, cellular immune deficiency, and chronic lymphatic leukemia.J Clin Invest1971https://conductscience.org/library/papers/4999540PubMed
181,084,353Suppression of B-cell differentiation by leukocytes from hypogammaglobulinemic patients.J Clin Invest1976https://conductscience.org/library/papers/1084353PubMed
191,083,420Suppressor cells: dependence on assay conditions for functional activity.J Exp Med1976https://conductscience.org/library/papers/1083420PubMed
201,082,888Suppressor thymus-derived lymphocytes in fungal infection.J Clin Invest1976https://conductscience.org/library/papers/1082888PubMed
211,080,834Impaired synthesis of polyclonal (non-paraprotein) immunoglobulins by circulating lymphocytes from patients with multiple myeloma Role of suppressor cells.N Engl J Med1975https://conductscience.org/library/papers/1080834PubMed
22780,023Is the B-cell abnormality secondary to T-cell abnormality in severe combined immunodeficiency?1.Clin Immunol Immunopathol1976https://conductscience.org/library/papers/780023PubMed

See all 21 references

Cited by17

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 63 citations.

PMIDTitleJournalYearIn PapersSource
35,095,915Good's Syndrome: Time to Move on From Reviewing the Past.Front Immunol2021https://conductscience.org/library/papers/35095915PubMed
7,141,511Lymphocyte subpopulations in primary immunodeficiency disorders.Indian J Pediatr1982https://conductscience.org/library/papers/7141511PubMed
6,976,248Glucocorticosteroid enhancement of immunoglobulin synthesis by pokeweed mitogen-stimulated human lymphocytes. III. Common variable immunodeficiency.Clin Exp Immunol1981https://conductscience.org/library/papers/6976248PubMed
6,969,155Subpopulations of human T lymphocytes. XV. T lymphocytes with receptors for IgA (T alpha), a distinct subpopulation of T lymphocytes. Studies in patients with primary immunodeficiency disorders.Clin Exp Immunol1980https://conductscience.org/library/papers/6969155PubMed
6,611,349Interleukin-2 correction of defective in vitro T-cell mitogenesis in patients with common varied immunodeficiency.J Clin Immunol1984https://conductscience.org/library/papers/6611349PubMed
6,446,430Abnormal B cell differentiation and variable increased T cell suppression in immunodeficiency with hyper-IgM.Clin Exp Immunol1980https://conductscience.org/library/papers/6446430PubMed
6,444,638Diminished synthesis of immunoglobulin by peripheral lymphocytes of patients with idiopathic membranous glomerulonephropathy.J Clin Invest1980https://conductscience.org/library/papers/6444638PubMed
6,439,743Polyclonal immunoglobulin secretion in patients with common variable immunodeficiency using monoclonal B cell differentiation factors.J Clin Invest1984https://conductscience.org/library/papers/6439743PubMed
6,327,761Epstein-Barr virus-induced lymphoblastoid cell lines derived from the peripheral blood of patients with X-linked agammaglobulinemia can secrete IgM.J Clin Immunol1984https://conductscience.org/library/papers/6327761PubMed
6,225,116Three distinct stages of B-cell defects in common varied immunodeficiency.Proc Natl Acad Sci U S A1982https://conductscience.org/library/papers/6225116PubMed
6,219,126Autologous mixed lymphocyte reaction in man. IV. Decreased autologous mixed lymphocyte culture response in patients with common variable immunodeficiency.J Clin Immunol1983https://conductscience.org/library/papers/6219126PubMed
6,181,087Polyclonal and antigen-specific B-cell responses in patients with common variable immunodeficiency.J Clin Immunol1982https://conductscience.org/library/papers/6181087PubMed
3,928,450Plasma cell infiltration of the small bowel: lack of evidence for a non-secretory form of alpha-heavy chain disease.Gut1985https://conductscience.org/library/papers/3928450PubMed
3,156,090B-cell function in common variable immunodeficiency: suppression of in vitro anti-sheep erythrocytes antibody production by T cells and monocytes.Immunology1985https://conductscience.org/library/papers/3156090PubMed
2,985,642Rescue of IgM, IgG, and IgA production in common varied immunodeficiency by T cell-independent stimulation with Epstein-Barr virus.J Clin Immunol1985https://conductscience.org/library/papers/2985642PubMed
1,395,097Immunophenotypical alterations in a subset of patients with common variable immunodeficiency (CVID).Clin Exp Immunol1992https://conductscience.org/library/papers/1395097PubMed
104,817Free immunoglobulin light chain synthesis by lymphocytes from patients with hypogammaglobulinaemia.Clin Exp Immunol1978https://conductscience.org/library/papers/104817PubMed

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Grants
  • Trials
  • Comments and corrections
  • Genes
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this paper from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/papers/v1/301145

GET https://conductscience.org/api/papers/v1/301145/references?page=2

API referenceFor AI assistants