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Paper · 319455

Transient accumulation of Okazaki fragments as a result of uracil incorporation into nascent DNA.

Tye BK and 4 others. Proc Natl Acad Sci U S A, 1977. Cited by 311 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Transient accumulation of Okazaki fragments as a result of uracil incorporation into nascent DNA. Papers, record 319455. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/319455

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Transient accumulation of Okazaki fragments as a result of uracil incorporation into nascent DNA.
PubMed
Journal
Proc Natl Acad Sci U S A
PubMed
Year
1977
PubMed
Publication types
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
311
iCite
Relative citation ratio, by iCite
6.71
iCite
Revised in PubMed
2019-05-01
PubMed

Authors5

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Tye BKB K
2Nyman POP O
3Lehman IRI R
4Hochhauser SS
5Weiss BB

Source PubMed

Topics12

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
DNA, BacterialMajor topic
GenesMajor topic
PyrophosphatasesMajor topic
Uracil NucleotidesMajor topic
Chromosome Mapping
DNA Repair
DNA Replication
Deoxyuridine
Escherichia coli
Molecular Weight
Mutation
Recombination, Genetic

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References11

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
214,085,395ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEOTIDES. II. FORMATION AND INTERCONVERSION OF DEOXYURIDINE PHOSPHATES.J Biol Chem1963https://conductscience.org/library/papers/14085395PubMed
313,901,467Deoxyuridylate kinase activity and deoxyuridinetriphosphatase in Escherichia coli.Proc Natl Acad Sci U S A1962https://conductscience.org/library/papers/13901467PubMed
54,943,548Slow joining of newly replicated DNA chains in DNA polymerase I-deficient Escherichia coli mutants.Proc Natl Acad Sci U S A1971https://conductscience.org/library/papers/4943548PubMed
6773,363Recalibrated linkage map of Escherichia coli K-12.Bacteriol Rev1976https://conductscience.org/library/papers/773363PubMed
75,959,459The deamination of cytidine and cytosine by acidic buffer solutions. Mutagenic implications.Biochemistry1966https://conductscience.org/library/papers/5959459PubMed
84,610,583An N-glycosidase from Escherichia coli that releases free uracil from DNA containing deaminated cytosine residues.Proc Natl Acad Sci U S A1974https://conductscience.org/library/papers/4610583PubMed
94,551,758Conditional lethality of recA and recB derivatives of a strain of Escherichia coli K-12 with a temperature-sensitive deoxyribonucleic acid polymerase I.J Bacteriol1972https://conductscience.org/library/papers/4551758PubMed
104,944,066Endonuclease II of Escherichia coli. Degradation of partially depurinated deoxyribonucleic acid.Biochemistry1971https://conductscience.org/library/papers/4944066PubMed
111,097,445Ten proteins required for conversion of phiX174 single-stranded DNA to duplex form in vitro. Resolution and reconstitution.J Biol Chem1975https://conductscience.org/library/papers/1097445PubMed
121,100,631Purification of Escherichia coli endonuclease specific for apurinic sites in DNA.J Biol Chem1975https://conductscience.org/library/papers/1100631PubMed

1 to 10 of 11

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Cited by97

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 311 citations.

PMIDTitleJournalYearIn PapersSource
42,935,372Uracil overload triggers global genome instability and dUTPdysgenesis.Nucleic Acids Res2026https://conductscience.org/library/papers/42935372PubMed
39,365,830Four decades of Eukaryotic DNA replication: From yeast genetics to high-resolution cryo-EM structures of the replisome.Proc Natl Acad Sci U S A2024https://conductscience.org/library/papers/39365830PubMed
38,358,250Crystal structure of the tegument protein UL82 (pp71) from human cytomegalovirus.Protein Sci2024https://conductscience.org/library/papers/38358250PubMed
37,376,646A Multimodal Approach towards Genomic Identification of Protein Inhibitors of Uracil-DNA Glycosylase.Viruses2023https://conductscience.org/library/papers/37376646PubMed
37,212,693Generation and Repair of Postreplication Gaps in Escherichia coli.Microbiol Mol Biol Rev2023https://conductscience.org/library/papers/37212693PubMed
32,249,353Diverse roles of nucleoside diphosphate kinase in genome stability and growth fitness.Curr Genet2020https://conductscience.org/library/papers/32249353PubMed
32,214,054The Essential Co-Option of Uracil-DNA Glycosylases by Herpesviruses Invites Novel Antiviral Design.Microorganisms2020https://conductscience.org/library/papers/32214054PubMed
31,459,598Highly Sensitive Detection of Uracil-DNA Glycosylase Activity Based on Self-Initiating Multiple Rolling Circle Amplification.ACS Omega2019https://conductscience.org/library/papers/31459598PubMed
31,431,505Genome-wide mapping of regions preferentially targeted by the human DNA-cytosine deaminase APOBEC3A using uracil-DNA pulldown and sequencing.J Biol Chem2019https://conductscience.org/library/papers/31431505PubMed
30,617,079Near-continuously synthesized leading strands in Escherichia coli are broken by ribonucleotide excision.Proc Natl Acad Sci U S A2019https://conductscience.org/library/papers/30617079PubMed

1 to 10 of 97

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Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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