Paper · 3280604

Regulation of gene expression by thyroid hormone.

Samuels HH and 3 others. J Clin Invest, 1988. Cited by 249 papers, by iCite.

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ConductScience Library. Regulation of gene expression by thyroid hormone. Papers, record 3280604. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/3280604

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Regulation of gene expression by thyroid hormone.; PubMed
Journal: J Clin Invest; PubMed
Year: 1988; PubMed
Publication types: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S., Review; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/3280604/; PubMed
DOI: https://doi.org/10.1172/jci113449; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC329618/; PubMed
The journal: https://conductscience.org/library/journal-index/7802877; PubMed
Citations, by iCite: 249; iCite
Relative citation ratio, by iCite: 6.52; iCite
Revised in PubMed: 2018-11-13; PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Samuels HH	H H
2	Forman BM	B M
3	Horowitz ZD	Z D
4	Ye ZS	Z S

Source PubMed

Topics5

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Gene Expression Regulation	Major topic
Thyroid Hormones	Major topic
Animals
Humans
Receptors, Thyroid Hormone

Source PubMed

Grants4

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes it	Agency	Country	NIH project	Stated by	Source
DK-16636	NIDDK NIH HHS	United States	R01DK016636	PubMed and NIH	NIH RePORTER
DK01372	NIDDK NIH HHS	United States	K08DK001372	PubMed and NIH	NIH RePORTER
			R37DK016636	NIH	NIH RePORTER
			R56DK016636	NIH	NIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References94

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	3,464,954	Repression mediates cell-type-specific expression of the rat growth hormone gene.	Proc Natl Acad Sci U S A	1986	https://conductscience.org/library/papers/3464954	PubMed
2	6,195,157	Molecular cloning of a cDNA sequence for rat malic enzyme. Direct evidence for induction in vivo of rat liver malic enzyme mRNA by thyroid hormone.	J Biol Chem	1983	https://conductscience.org/library/papers/6195157	PubMed
3	3,736,673	Discrete cis-active genomic sequences dictate the pituitary cell type-specific expression of rat prolactin and growth hormone genes.	Nature	1986	https://conductscience.org/library/papers/3736673	PubMed
4	4,055,787	Regulation of growth hormone mRNA synthesis by 3,5,3'-triiodo-L-thyronine in cultured growth hormone-producing rat pituitary tumor cells (GC cells). Dissociation between nuclear iodothyronine receptor concentration and growth hormone mRNA synthesis during the deoxyribonucleic acid synthesis phase of the cell cycle.	J Biol Chem	1985	https://conductscience.org/library/papers/4055787	PubMed
5	6,309,413	Role of the v-erbA and v-erbB oncogenes of avian erythroblastosis virus in erythroid cell transformation.	Cell	1983	https://conductscience.org/library/papers/6309413	PubMed
6	197,080	Modulation of thyroid hormone nuclear receptor levels by 3,5,3'-triiodo-L-thyronine in GH1 cells. Evidence for two functional components of nuclear-bound receptor and relationship to the induction of growth hormone synthesis.	J Biol Chem	1977	https://conductscience.org/library/papers/197080	PubMed
7	6,323,162	Chromosomal localisation of the human homologues to the oncogenes erbA and B.	EMBO J	1984	https://conductscience.org/library/papers/6323162	PubMed
8	217,638	Nuclear triiodothyronine receptor sites in brain: probable identity with hepatic receptors and regional distribution.	Endocrinology	1978	https://conductscience.org/library/papers/217638	PubMed
9	2,879,242	The c-erb-A protein is a high-affinity receptor for thyroid hormone.	Nature	1986	https://conductscience.org/library/papers/2879242	PubMed
10	49,266	Rapid effects of single small doses of L-thyroxine and triiodo-L-thyronine on growth hormone, as studied in the rat by radioimmunoassy.	Endocrinology	1975	https://conductscience.org/library/papers/49266	PubMed

1 to 10 of 94

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Cited by42

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 249 citations.

PMID	Title	Journal	Year	In Papers	Source
27,580,811	Gene Expression in Mouse Thyrotrope Adenoma: Transcription Elongation Factor Stimulates Proliferation.	Endocrinology	2016	https://conductscience.org/library/papers/27580811	PubMed
24,288,132	Novel mechanism of positive versus negative regulation by thyroid hormone receptor β1 (TRβ1) identified by genome-wide profiling of binding sites in mouse liver.	J Biol Chem	2014	https://conductscience.org/library/papers/24288132	PubMed
21,664,427	Effects of the thyroid hormone derivatives 3-iodothyronamine and thyronamine on rat liver oxidative capacity.	Mol Cell Endocrinol	2011	https://conductscience.org/library/papers/21664427	PubMed
18,280,526	Non-genomic actions of thyroid hormone in brain development.	Steroids	2008	https://conductscience.org/library/papers/18280526	PubMed
18,238,828	Participation of Brahma-related gene 1 (BRG1)-associated factor 57 and BRG1-containing chromatin remodeling complexes in thyroid hormone-dependent gene activation during vertebrate development.	Mol Endocrinol	2008	https://conductscience.org/library/papers/18238828	PubMed
17,906,368	The menace of endocrine disruptors on thyroid hormone physiology and their impact on intrauterine development.	Endocrine	2007	https://conductscience.org/library/papers/17906368	PubMed
16,604,174	Nuclear receptor corepressors.	Nucl Recept Signal	2003	https://conductscience.org/library/papers/16604174	PubMed
12,926,518	Expression of thyroid hormone receptors in intracranial meningiomas.	Kaohsiung J Med Sci	2003	https://conductscience.org/library/papers/12926518	PubMed
11,713,274	Domain structure of the NRIF3 family of coregulators suggests potential dual roles in transcriptional regulation.	Mol Cell Biol	2001	https://conductscience.org/library/papers/11713274	PubMed
11,171,071	Regulation of mucin gene expression in human tracheobronchial epithelial cells by thyroid hormone.	Biochem J	2001	https://conductscience.org/library/papers/11171071	PubMed

1 to 10 of 42

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Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

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PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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