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Paper329142

Epidermal Langerhans cells express Ia antigens.

Klareskog L and 3 others. Nature, 1977. Cited by 363 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Epidermal Langerhans cells express Ia antigens. Papers, record 329142. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/329142

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Epidermal Langerhans cells express Ia antigens.
PubMed
Journal
Nature
PubMed
Year
1977
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
363
iCite
Relative citation ratio, by iCite
8.71
iCite
Revised in PubMed
2019-06-17
PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Klareskog LL
2Tjernlund UU
3Forsum UU
4Peterson PAP A

Source PubMed

Topics12

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
IsoantigensMajor topic
Langerhans CellsMajor topic
SkinMajor topic
B-Lymphocytes
Dermatitis, Contact
Female
Fluorescent Antibody Technique
HLA Antigens
Humans
Keratins
Melanocytes
Molecular Weight

Source PubMed

Cited by87

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 363 citations.

PMIDTitleJournalYearIn PapersSource
41,180,114Langerin+ Dendritic Cells in Cutaneous Fibrosis: The TGF-β1 Signaling Axis.Clin Cosmet Investig Dermatol2025https://conductscience.org/library/papers/41180114PubMed
36,905,506Phenotypes and Functions of Human Dendritic Cell Subsets in the Tumor Microenvironment.Methods Mol Biol2023https://conductscience.org/library/papers/36905506PubMed
36,851,328Skin-Based Vaccination: A Systematic Mapping Review of the Types of Vaccines and Methods Used and Immunity and Protection Elicited in Pigs.Vaccines (Basel)2023https://conductscience.org/library/papers/36851328PubMed
33,644,059Primary Cilia in the Skin: Functions in Immunity and Therapeutic Potential.Front Cell Dev Biol2021https://conductscience.org/library/papers/33644059PubMed
30,105,033Uncovering the Mysteries of Langerhans Cells, Inflammatory Dendritic Epidermal Cells, and Monocyte-Derived Langerhans Cell-Like Cells in the Epidermis.Front Immunol2018https://conductscience.org/library/papers/30105033PubMed
29,295,520The Origin of Skin Dendritic Cell Network and Its Role in Psoriasis.Int J Mol Sci2017https://conductscience.org/library/papers/29295520PubMed
28,926,543Ontogeny and function of murine epidermal Langerhans cells.Nat Immunol2017https://conductscience.org/library/papers/28926543PubMed
26,554,892Langerhans cell origin and regulation.Curr Opin Hematol2016https://conductscience.org/library/papers/26554892PubMed
25,301,671Human skin dendritic cells in health and disease.J Dermatol Sci2015https://conductscience.org/library/papers/25301671PubMed
21,475,006StrataGraft skin substitute is well-tolerated and is not acutely immunogenic in patients with traumatic wounds: results from a prospective, randomized, controlled dose escalation trial.Ann Surg2011https://conductscience.org/library/papers/21475006PubMed
21,302,100Expression of ia antigens by murine keratinizing epithelial langerhans cells.Immunogenetics1978https://conductscience.org/library/papers/21302100PubMed
20,193,016Langerhans cells and more: langerin-expressing dendritic cell subsets in the skin.Immunol Rev2010https://conductscience.org/library/papers/20193016PubMed
19,679,220Development of an ex vivo human skin model for intradermal vaccination: tissue viability and Langerhans cell behaviour.Vaccine2009https://conductscience.org/library/papers/19679220PubMed
15,147,350Langerhans cells from human oral epithelium are more effective at stimulating allogeneic T cells in vitro than Langerhans cells from skin.Clin Exp Immunol2004https://conductscience.org/library/papers/15147350PubMed
14,991,068Langerhans cells utilize CD1a and langerin to efficiently present nonpeptide antigens to T cells.J Clin Invest2004https://conductscience.org/library/papers/14991068PubMed
14,991,060CD1a and langerin: acting as more than Langerhans cell markers.J Clin Invest2004https://conductscience.org/library/papers/14991060PubMed
12,945,733Langerhans cell-like dendritic cells in the cornea, tongue and oesophagus of the chicken (Gallus gallus).Histochem J2002https://conductscience.org/library/papers/12945733PubMed
11,809,842Birbeck granules are subdomains of endosomal recycling compartment in human epidermal Langerhans cells, which form where Langerin accumulates.Mol Biol Cell2002https://conductscience.org/library/papers/11809842PubMed
11,563,545Non-specific esterase-positive dendritic cells in epithelia of the frog Rana pipiens.Histochem J2001https://conductscience.org/library/papers/11563545PubMed
8,727,021Contact dermatitis. Clinical perspectives and basic mechanisms.Clin Rev Allergy Immunol1996https://conductscience.org/library/papers/8727021PubMed

See all 87 cited by

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

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Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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