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Paper · 33420102

Development of a structural epitope mimic: an idiotypic approach to HCV vaccine design.

Cowton VM and 11 others. NPJ Vaccines, 2021. Cited by 14 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Development of a structural epitope mimic: an idiotypic approach to HCV vaccine design. Papers, record 33420102. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/33420102

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Development of a structural epitope mimic: an idiotypic approach to HCV vaccine design.
PubMed
Journal
NPJ Vaccines
PubMed
Year
2021
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
14
iCite
Relative citation ratio, by iCite
0.83
iCite
Revised in PubMed
2025-05-30
PubMed

Authors12

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Cowton VMVanessa Mhttps://orcid.org/0000-0003-1813-7825
2Owsianka AMAnia M
3Fadda VValeriahttps://orcid.org/0000-0002-0043-7208
4Ortega-Prieto AMAna Mariahttps://orcid.org/0000-0002-9023-0103
5Cole SJSarah J
6Potter JAJane A
7Skelton JKJessica K
8Jeffrey NNathan
9Di Lorenzo CCaterina
10Dorner MMarcus

1 to 10 of 12Source PubMed

See all 12 authors

Topics0

NLM's MeSH indexing of the paper, its major topics first.

None in this release.

Grants6

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated by
MC_UU12014/2RCUK | Medical Research Council (MRC)PubMed
104771/Z/14/ZWellcome Trust (Wellcome)PubMed
MC_EX_G0801770RCUK | Medical Research Council (MRC)PubMed
Wellcome TrustUnited KingdomPubMed
ERC-StG-2015-637304EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council)PubMed
MC_UU_12014/2Medical Research CouncilUnited KingdomPubMed

Source PubMed

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References68

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
16,985,352Recurrent idiotopes and internal images.EMBO J1982https://conductscience.org/library/papers/6985352PubMed
216,369,096Scaling and assessment of data quality.Acta Crystallogr D Biol Crystallogr2006https://conductscience.org/library/papers/16369096PubMed
319,397,930A reporter cell line for rapid and sensitive evaluation of hepatitis C virus infectivity and replication.Antiviral Res2009https://conductscience.org/library/papers/19397930PubMed
426,710,081Monoclonal anti-envelope antibody AP33 protects humanized mice against a patient-derived hepatitis C virus challenge.Hepatology2016https://conductscience.org/library/papers/26710081PubMed
51,690,598Epitope mapping and use of anti-idiotypic antibodies to the L6 monoclonal anticarcinoma antibody.Cancer Res1990https://conductscience.org/library/papers/1690598PubMed
620,124,702PHENIX: a comprehensive Python-based system for macromolecular structure solution.Acta Crystallogr D Biol Crystallogr2010https://conductscience.org/library/papers/20124702PubMed
723,935,648Structural and antigenic definition of hepatitis C virus E2 glycoprotein epitopes targeted by monoclonal antibodies.Clin Dev Immunol2013https://conductscience.org/library/papers/23935648PubMed
823,698,367Self-assembling influenza nanoparticle vaccines elicit broadly neutralizing H1N1 antibodies.Nature2013https://conductscience.org/library/papers/23698367PubMed
916,103,160Monoclonal antibody AP33 defines a broadly neutralizing epitope on the hepatitis C virus E2 envelope glycoprotein.J Virol2005https://conductscience.org/library/papers/16103160PubMed
1025,473,061Structural flexibility of a conserved antigenic region in hepatitis C virus glycoprotein E2 recognized by broadly neutralizing antibodies.J Virol2015https://conductscience.org/library/papers/25473061PubMed

Cited by12

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 14 citations.

PMIDTitleJournalYearIn PapersSource
42,742,346Anti-idiotypic antibodies as molecular mimics of conserved influenza hemagglutinin epitopes.Protein Sci2026https://conductscience.org/library/papers/42742346PubMed
39,852,814Anti-Idiotypic Antibody as a Booster Vaccine Against Respiratory Syncytial Virus.Vaccines (Basel)2025https://conductscience.org/library/papers/39852814PubMed
39,575,309Epitope-based therapeutic targets in HCV genotype 1 non-structural proteins: a novel strategy to combat emerging drug resistance.Front Cell Infect Microbiol2024https://conductscience.org/library/papers/39575309PubMed
38,271,227A novel strategy for an anti-idiotype vaccine: nanobody mimicking neutralization epitope of porcine circovirus type 2.J Virol2024https://conductscience.org/library/papers/38271227PubMed
37,647,422Therapeutic strategies and promising vaccine for hepatitis C virus infection.Immun Inflamm Dis2023https://conductscience.org/library/papers/37647422PubMed
36,934,116Hepatitis C virus E1 and modified E2 delivered from an mRNA vaccine induces protective immunity.NPJ Vaccines2023https://conductscience.org/library/papers/36934116PubMed
36,482,074Potential of an anti-bevacizumab idiotype scFv DNA-based immunization to elicit VEGF-binding antibody response.Gene Ther2023https://conductscience.org/library/papers/36482074PubMed
36,379,958Two-component vaccine consisting of virus-like particles displaying hepatitis C virus envelope protein 2 oligomers.NPJ Vaccines2022https://conductscience.org/library/papers/36379958PubMed
35,761,816Production and immunogenicity of different prophylactic vaccines for hepatitis C virus (Review).Exp Ther Med2022https://conductscience.org/library/papers/35761816PubMed
35,015,104[Development approaches for vaccines against hepatitis C virus infections].Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz2022https://conductscience.org/library/papers/35015104PubMed

1 to 10 of 12

See all 12 cited by

Genes6

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
ALB213PubTator's text mininghttps://conductscience.org/library/genes/213NCBI Gene
FANCB2,187PubTator's text mininghttps://conductscience.org/library/genes/2187NCBI Gene
IGK50,802PubTator's text mininghttps://conductscience.org/library/genes/50802NCBI Gene
LIPC3,990PubTator's text mininghttps://conductscience.org/library/genes/3990NCBI Gene
MBP4,155PubTator's text mininghttps://conductscience.org/library/genes/4155NCBI Gene
SCFV652,070PubTator's text mininghttps://conductscience.org/library/genes/652070NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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