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Paper355125

Direct blockade of antigen-reactive B lymphocytes by immune complexes. An 'off' signal for precursors of IgM-producing cells provided by the linkage of antigen-and Fc-receptors.

Oberbarnscheidt J and 1 other. Immunology, 1978. Cited by 75 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Direct blockade of antigen-reactive B lymphocytes by immune complexes. An 'off' signal for precursors of IgM-producing cells provided by the linkage of antigen-and Fc-receptors. Papers, record 355125. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/355125

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Direct blockade of antigen-reactive B lymphocytes by immune complexes. An 'off' signal for precursors of IgM-producing cells provided by the linkage of antigen-and Fc-receptors.
PubMed
Journal
Immunology
PubMed
Year
1978
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
75
iCite
Relative citation ratio, by iCite
1.96
iCite
Revised in PubMed
2021-12-03
PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Oberbarnscheidt JJ
2Kölsch EE

Source PubMed

Topics14

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Antibody FormationMajor topic
Antigen-Antibody ComplexMajor topic
B-LymphocytesMajor topic
Immunoglobulin Fc FragmentsMajor topic
Animals
Antibody-Producing Cells
Binding Sites
Female
Hemolytic Plaque Technique
Immunoglobulin M
Immunosuppression Therapy
Male
Mice
Time Factors

Source PubMed

References25

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
114,319,411ANTIBODY SYNTHESIS AT THE CELLULAR LEVEL. ANTIBODY-INDUCED SUPPRESSION OF 19S AND 7S ANTIBODY RESPONSE.J Exp Med1965https://conductscience.org/library/papers/14319411PubMed
266,280Effects of carrageenan on immune responses. Studies on the macrophage dependency of various antigens after treatment with carrageenan.J Immunol1977https://conductscience.org/library/papers/66280PubMed
31,086,339Control of B-lymphocyte function. I. Inactivation of mitogenesis by interactions with surface immunoglobulin and Fc-receptor molecules.J Exp Med1976https://conductscience.org/library/papers/1086339PubMed
41,085,699Requirement for accessory cells in the antibody response to T cell-independent antigens in vitro.Eur J Immunol1976https://conductscience.org/library/papers/1085699PubMed
54,610,054Separation of mouse spleen cells by passage through columns of sephadex G-10.J Immunol Methods1974https://conductscience.org/library/papers/4610054PubMed
64,605,029Regulation of the immune response. V. Antibody-mediated inhibition of T and B cell cooperation in the in vitro response to red cell antigens.Eur J Immunol1974https://conductscience.org/library/papers/4605029PubMed
756,009Selective suppression of immune responses. Regulation of antibody formation and cell-mediated immunity by antibody.Prog Allergy1975https://conductscience.org/library/papers/56009PubMed
84,576,501Inhibition of the immune response by 7S antibody mechanism and site of action.J Exp Med1973https://conductscience.org/library/papers/4576501PubMed
94,580,667Regulation of the immune response. IV. Antibody-mediated suppression of the immune response to haptens and heterologous erythrocyte antigens in vitro.J Immunol1973https://conductscience.org/library/papers/4580667PubMed
105,061,825Enhancement of antibody synthesis in vitro by mercaptoethanol.Cell Immunol1972https://conductscience.org/library/papers/5061825PubMed
114,938,448Nonantigenicity and immunologic tolerance: the role of the carrier in the induction of tolerance to the hapten.J Exp Med1971https://conductscience.org/library/papers/4938448PubMed
124,911,555An in vitro primary immune response to 2,4,6-trinitrophenyl substituted erythrocytes: response against carrier and hapten.J Immunol1970https://conductscience.org/library/papers/4911555PubMed
134,928,749The mechanism of antibody-induced stimulation and inhibition of the immune response.J Immunol1971https://conductscience.org/library/papers/4928749PubMed
144,874,538Regulatory effect of antibody on the immune response.Adv Immunol1968https://conductscience.org/library/papers/4874538PubMed
155,306,610Inhibition of the immune response in vitro to sheep red blood cells by passive antibody.Nature1969https://conductscience.org/library/papers/5306610PubMed
16803,415Suppression and augmentation of the primary in vitro immune response by different classes of antibodies.Cell Immunol1975https://conductscience.org/library/papers/803415PubMed
171,093,468A T-cell -produced mediator substance active in the humoral immune response.Ann N Y Acad Sci1975https://conductscience.org/library/papers/1093468PubMed
181,092,484Regulation of the immune response. IX. Resistance to antibody mediated immunosuppression induced by the presence of the allogeneic effect.Cell Immunol1975https://conductscience.org/library/papers/1092484PubMed
191,084,368Suppressor cells in spleens from "nude" mice: their effect on the mitogenic response of B lymphocytes.J Immunol1976https://conductscience.org/library/papers/1084368PubMed
201,079,850Suppression of in vitro antibody synthesis by immunoglobulin-binding factor.J Exp Med1975https://conductscience.org/library/papers/1079850PubMed

See all 25 references

Cited by19

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 75 citations.

PMIDTitleJournalYearIn PapersSource
8,151,158Immunoregulatory characteristics of the in vitro anti-ssDNA response.Immunol Res1993https://conductscience.org/library/papers/8151158PubMed
7,007,223Immunoregulatory effects of covalent antigen-antibody complexes. III. Enhancement or suppression depending on the time of administration of complex relative to a T-independent antigen.Immunology1981https://conductscience.org/library/papers/7007223PubMed
6,978,206TG cells in peripheral blood lymphocytes from patients with rheumatoid arthritis.Clin Exp Immunol1981https://conductscience.org/library/papers/6978206PubMed
6,970,175Peritoneal exudate T lymphocytes with specificity to sheep red blood cells. IV. Fc receptors on specific peritoneal exudate lymphocytes and their role in delayed-type hypersensitivity reactions.Immunology1981https://conductscience.org/library/papers/6970175PubMed
6,749,658Characteristics and function of Fc receptors on human lymphocytes.Immunology1982https://conductscience.org/library/papers/6749658PubMed
6,725,532IgG aggregates of different sizes stimulate or suppress Ig secretion by human lymphocytes in vitro.J Clin Immunol1984https://conductscience.org/library/papers/6725532PubMed
6,674,205Immune complexes: biochemical and biological aspects.Indian J Pediatr1983https://conductscience.org/library/papers/6674205PubMed
6,447,230Pathopysiological aspects of immune complex diseases. Part II. Phagocytosis, exocytosis, and pathogenic depositions.Klin Wochenschr1980https://conductscience.org/library/papers/6447230PubMed
6,360,850Monoclonal SBF produced by a hybridoma: in-vitro and in-vivo suppression of B tumour-cell proliferation.Immunology1983https://conductscience.org/library/papers/6360850PubMed
6,350,167Suppressive B-cell factor (SBF) produced by FcR-bearing B cells; suppression of B, but not non-B-cell proliferation.Immunology1983https://conductscience.org/library/papers/6350167PubMed
6,201,437Facb rosette-forming cells in mice: studies on their functional significance.Immunology1984https://conductscience.org/library/papers/6201437PubMed
6,194,337The biological properties of immunoglobulin G and its split products [F(ab')2 and Fab].Klin Wochenschr1983https://conductscience.org/library/papers/6194337PubMed
6,111,406Serum-mediated inhibition of lymphocyte Fc gamma receptors in glomerulonephritis.Clin Exp Immunol1980https://conductscience.org/library/papers/6111406PubMed
3,958,183Prognostic role of antibody reactivity to melanoma.J Clin Invest1986https://conductscience.org/library/papers/3958183PubMed
3,933,869Modulation of the immune response by immunoglobulin for intravenous use. I. Inhibition of pokeweed mitogen-induced B cell differentiation.Clin Exp Immunol1985https://conductscience.org/library/papers/3933869PubMed
3,558,734Bovine milk IgG, but not serum IgG, inhibits pokeweed mitogen-induced antibody secretion by human peripheral blood mononuclear cells.J Clin Immunol1987https://conductscience.org/library/papers/3558734PubMed
3,155,932Lymphocytes bearing Fc gamma receptors in rheumatoid arthritis. II. Phenotypic characterisation of mononuclear cells forming Facb rosettes in RA.Ann Rheum Dis1985https://conductscience.org/library/papers/3155932PubMed
3,108,141Inhibitory mechanism of the proliferative response of B lymphocytes: suppression of the proliferation induced by anti-mu antibody and BSF1 by immune complexes.Immunology1987https://conductscience.org/library/papers/3108141PubMed
315,923Immunoregulation by covalent antigen-antibody complexes. II. Suppression of a T-cell independent anti-hapten response.Immunology1979https://conductscience.org/library/papers/315923PubMed

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

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  • ClinicalTrials.govNo license stated
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  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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