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Paper · 37683045

Replication cycle timing determines phage sensitivity to a cytidine deaminase toxin/antitoxin bacterial defense system.

Hsueh BY and 4 others. PLoS Pathog, 2023. Cited by 13 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Replication cycle timing determines phage sensitivity to a cytidine deaminase toxin/antitoxin bacterial defense system. Papers, record 37683045. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/37683045

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Replication cycle timing determines phage sensitivity to a cytidine deaminase toxin/antitoxin bacterial defense system.
PubMed
Journal
PLoS Pathog
PubMed
Year
2023
PubMed
Publication types
Journal Article, Research Support, N.I.H., Extramural
PubMed
Citations, by iCite
13
iCite
Relative citation ratio, by iCite
1.11
iCite
Revised in PubMed
2024-07-23
PubMed

Authors5

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Hsueh BYBrian Y
2Ferrell MJMicah J
3Sanath-Kumar RRam
4Bedore AMAmber M
5Waters CMChristopher Mhttps://orcid.org/0000-0003-2336-7836

Source PubMed

Topics6

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
AntitoxinsMajor topic
BacteriophagesMajor topic
Cytidine Deaminase
Bacteria
Nucleotides
RNA

Source PubMed

Grants3

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
R01 AI158433NIAID NIH HHSUnited StatesR01AI158433PubMed and NIHNIH RePORTER
R01 NR008052NINR NIH HHSUnited StatesR01NR008052PubMedNIH RePORTER
R35 GM139537NIGMS NIH HHSUnited StatesR35GM139537PubMed and NIHNIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections1

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

KindPMIDTitleIn Papers
Update of36,798,279

Source PubMed

References54

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
118,521,572Effects of luxCDABEG induction in Vibrio fischeri: enhancement of symbiotic colonization and conditional attenuation of growth in culture.Arch Microbiol2008https://conductscience.org/library/papers/18521572PubMed
227,497,318Evolved Populations of Shigella flexneri Phage Sf6 Acquire Large Deletions, Altered Genomic Architecture, and Faster Life Cycles.Genome Biol Evol2016https://conductscience.org/library/papers/27497318PubMed
332,937,646Prokaryotic viperins produce diverse antiviral molecules.Nature2021https://conductscience.org/library/papers/32937646PubMed
415,718,296Toxin-antitoxin loci are highly abundant in free-living but lost from host-associated prokaryotes.Nucleic Acids Res2005https://conductscience.org/library/papers/15718296PubMed
523,093,930Determining host metabolic limitations on viral replication via integrated modeling and experimental perturbation.PLoS Comput Biol2012https://conductscience.org/library/papers/23093930PubMed
631,533,127Cyclic GMP-AMP signalling protects bacteria against viral infection.Nature2019https://conductscience.org/library/papers/31533127PubMed
713,888,713Host specificity of DNA produced by Escherichia coli. II. Control over acceptance of DNA from infecting phage lambda.J Mol Biol1962https://conductscience.org/library/papers/13888713PubMed
833,838,104Shutoff of host transcription triggers a toxin-antitoxin system to cleave phage RNA and abort infection.Mol Cell2021https://conductscience.org/library/papers/33838104PubMed
98,411,153Plasmid addiction genes of bacteriophage P1: doc, which causes cell death on curing of prophage, and phd, which prevents host death when prophage is retained.J Mol Biol1993https://conductscience.org/library/papers/8411153PubMed
1035,725,776The DarTG toxin-antitoxin system provides phage defence by ADP-ribosylating viral DNA.Nat Microbiol2022https://conductscience.org/library/papers/35725776PubMed

Cited by12

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 13 citations.

PMIDTitleJournalYearIn PapersSource
41,285,378Battle beyond membrane: flagella as a conduit for phage DNA entry and a trigger for bacterial defense in Yersinia enterocolitica.Nucleic Acids Res2025https://conductscience.org/library/papers/41285378PubMed
41,279,190Targeting multidrug-resistant bacteria with genetic-information-free protein-only phages.bioRxiv2025https://conductscience.org/library/papers/41279190PubMed
40,904,118Defence systems encoded by core genomic islands of seventh pandemic Vibrio cholerae.Philos Trans R Soc Lond B Biol Sci2025https://conductscience.org/library/papers/40904118PubMed
40,730,656Manipulation of the nucleotide pool in human, bacterial and plant immunity.Nat Rev Immunol2026https://conductscience.org/library/papers/40730656PubMed
40,695,854Bioinformatic exploration reveals features of tenpIN family of type III toxin-antitoxin systems in bacteria and viruses.Sci Rep2025https://conductscience.org/library/papers/40695854PubMed
40,568,932An archaeal chronic virus escapes the immunity of prokaryotic Argonaute.Nucleic Acids Res2025https://conductscience.org/library/papers/40568932PubMed
40,169,592A toxin-antitoxin system provides phage defense via DNA damage and repair.Nat Commun2025https://conductscience.org/library/papers/40169592PubMed
40,052,347Insight into the environmental cues modulating the expression of bacterial toxin-antitoxin systems.FEMS Microbiol Rev2025https://conductscience.org/library/papers/40052347PubMed
39,777,537Molecular and genetic analysis of methicillin-resistant Staphylococcus aureus (MRSA) in a tertiary care hospital in Saudi Arabia.Naunyn Schmiedebergs Arch Pharmacol2025https://conductscience.org/library/papers/39777537PubMed
39,445,801Conformational change as a mechanism for toxin activation in bacterial toxin-antitoxin systems.J Virol2024https://conductscience.org/library/papers/39445801PubMed

1 to 10 of 12

See all 12 cited by

Genes3

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
AVSD17,446PubTator's text mininghttps://conductscience.org/library/genes/7446NCBI Gene
CDA978PubTator's text mininghttps://conductscience.org/library/genes/978NCBI Gene
DCTD1,635PubTator's text mininghttps://conductscience.org/library/genes/1635NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data1

The data bank entries PubMed's record names. Trial numbers are under Trials.

Data bankAccession
figshare10.6084/m9.figshare.22028480.v1

Source figshare

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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