Paper377283

Direct chemical method for sequencing RNA.

Peattie DA. Proc Natl Acad Sci U S A, 1979. Cited by 965 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Direct chemical method for sequencing RNA. Papers, record 377283. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/377283

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Direct chemical method for sequencing RNA.; PubMed
Journal: Proc Natl Acad Sci U S A; PubMed
Year: 1979; PubMed
Publication types: Journal Article, Research Support, U.S. Gov't, P.H.S.; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/377283/; PubMed
DOI: https://doi.org/10.1073/pnas.76.4.1760; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC383470/; PubMed
The journal: https://conductscience.org/library/journal-index/7505876; PubMed
Citations, by iCite: 965; iCite
Relative citation ratio, by iCite: 19.8; iCite
Revised in PubMed: 2024-01-09; PubMed

Authors1

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Peattie DA	D A

Source PubMed

Topics10

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
RNA	Major topic
Base Sequence
Chemical Phenomena
Chemistry
Indicators and Reagents
Methods
Molecular Weight
Nucleic Acid Conformation
Ribonucleotides
Saccharomyces cerevisiae

Source PubMed

Show 4 more topicsShow fewer topics

References27

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	16,748,923	The reaction of mono- and di-functional alkylating agents with nucleic acids.	Biochem J	1961	https://conductscience.org/library/papers/16748923	PubMed
2	14,254,018	STUDIES OF THE NUCLEOTIDE ARRANGEMENT IN DEOXYRIBONUCLEIC ACIDS. IX. SELECTIVE DEGRADATION OF PYRIMIDINE DEOXYRIBONUCLEOTIDES.	Biochim Biophys Acta	1964	https://conductscience.org/library/papers/14254018	PubMed
3	14,217,878	NUCLEOTIDE SEQUENCE ANALYSIS OF POLYRIBONUCLEOTIDES BY MEANS OF PERIODATE OXIDATION FOLLOWED BY CLEAVAGE WITH AN AMINE.	J Biol Chem	1964	https://conductscience.org/library/papers/14217878	PubMed
4	13,996,927	A specific partial hydrolysis procedure for soluble RNA.	Biochim Biophys Acta	1963	https://conductscience.org/library/papers/13996927	PubMed
6	25,417	Sequence analysis of 5'[32P] labeled mRNA and tRNA using polyacrylamide gel electrophoresis.	Nucleic Acids Res	1978	https://conductscience.org/library/papers/25417	PubMed
7	270,752	The nucleotide sequences of the untranslated 5' regions of human alpha- and beta-globin mRNAs.	Proc Natl Acad Sci U S A	1977	https://conductscience.org/library/papers/270752	PubMed
8	67,896	Complete nucleotide sequence of the 5' noncoding region of rabbit beta-globin mRNA.	Cell	1977	https://conductscience.org/library/papers/67896	PubMed
9	724,498	Reactions at the termini of tRNA with T4 RNA ligase.	Nucleic Acids Res	1978	https://conductscience.org/library/papers/724498	PubMed
10	662,002	A different approach to RNA sequencing.	Nature	1978	https://conductscience.org/library/papers/662002	PubMed
11	82,934	Analysis of the 3'-terminal nucleotide sequence of vesicular stomatitis virus N protein mRNA.	Nucleic Acids Res	1978	https://conductscience.org/library/papers/82934	PubMed
12	81,487	3'-terminal nucleotide sequence of encephalomyocarditis virus RNA determined by reverse transcriptase and chain-terminating inhibitors.	Proc Natl Acad Sci U S A	1978	https://conductscience.org/library/papers/81487	PubMed
13	71,351	Rapid gel sequencing of RNA by primed synthesis with reverse transcriptase.	J Mol Biol	1977	https://conductscience.org/library/papers/71351	PubMed
14	409,999	Mapping adenines, guanines, and pyrimidines in RNA.	Nucleic Acids Res	1977	https://conductscience.org/library/papers/409999	PubMed
15	347,396	Application of a rapid gel method to the sequencing of fragments of 16S ribosomal RNA from Escherichia coli.	Nucleic Acids Res	1978	https://conductscience.org/library/papers/347396	PubMed
16	353,742	The degradation of DNA by hydrazine: identification of 3-ureidopyrazole as a product of the hydrazinolysis of deoxycytidylic acid residues.	Nucleic Acids Res	1978	https://conductscience.org/library/papers/353742	PubMed
17	281,683	RNA sequencing with radioactive chain-terminating ribonucleotides.	Proc Natl Acad Sci U S A	1978	https://conductscience.org/library/papers/281683	PubMed
18	265,521	A new method for sequencing DNA.	Proc Natl Acad Sci U S A	1977	https://conductscience.org/library/papers/265521	PubMed
19	631,324	The use of thin acrylamide gels for DNA sequencing.	FEBS Lett	1978	https://conductscience.org/library/papers/631324	PubMed
20	592,379	The sequence of a region of bacteriophage phiX174 DNA coding for parts of genes A and B.	J Mol Biol	1977	https://conductscience.org/library/papers/592379	PubMed
21	927,512	New rapid gel sequencing method for RNA.	Nature	1977	https://conductscience.org/library/papers/927512	PubMed

Show 14 more referencesShow fewer referencesSee all 27 references

Cited by445

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 965 citations.

PMID	Title	Journal	Year	In Papers	Source
42,606,910	Quantum chemical profiling of the electronic structure and hydrolytic stability of modified ribonucleosides.	Phys Chem Chem Phys	2026	https://conductscience.org/library/papers/42606910	PubMed
41,385,321	Beyond RNA modification: a novel role for tRNA modifying enzyme in oxidative stress response and metabolism.	Nucleic Acids Res	2025	https://conductscience.org/library/papers/41385321	PubMed
41,271,707	Mapping of HOCl-oxidized RNA identifies abasic sites as major damage and oxidation product of oxo8G.	Nat Commun	2025	https://conductscience.org/library/papers/41271707	PubMed
40,951,988	Discovery of RNA-Reactive Small Molecules Guides the Design of Electrophilic Modules for RNA-Specific Covalent Binders.	J Am Chem Soc	2025	https://conductscience.org/library/papers/40951988	PubMed
40,206,865	The detection, function, and therapeutic potential of RNA 2'-O-methylation.	Innov Life	2025	https://conductscience.org/library/papers/40206865	PubMed
39,953,096	Chemical reactivity of RNA and its modifications with hydrazine.	Commun Chem	2025	https://conductscience.org/library/papers/39953096	PubMed
39,224,931	Targeting RNA with small molecules, from RNA structures to precision medicines: IUPHAR review: 40.	Br J Pharmacol	2024	https://conductscience.org/library/papers/39224931	PubMed
38,566,310	Global and single-nucleotide resolution detection of 7-methylguanosine in RNA.	RNA Biol	2024	https://conductscience.org/library/papers/38566310	PubMed
38,065,564	General Principles and Limitations for Detection of RNA Modifications by Sequencing.	Acc Chem Res	2024	https://conductscience.org/library/papers/38065564	PubMed
36,747,354	Rock, scissors, paper: How RNA structure informs function.	Plant Cell	2023	https://conductscience.org/library/papers/36747354	PubMed
36,387,283	An overview of structural approaches to study therapeutic RNAs.	Front Mol Biosci	2022	https://conductscience.org/library/papers/36387283	PubMed
35,941,229	Targeting RNA structures with small molecules.	Nat Rev Drug Discov	2022	https://conductscience.org/library/papers/35941229	PubMed
35,445,501	The plant epitranscriptome: revisiting pseudouridine and 2'-O-methyl RNA modifications.	Plant Biotechnol J	2022	https://conductscience.org/library/papers/35445501	PubMed
34,696,322	Chemical and Enzymatic Probing of Viral RNAs: From Infancy to Maturity and Beyond.	Viruses	2021	https://conductscience.org/library/papers/34696322	PubMed
34,480,848	Recent technical advances in the study of nucleic acid modifications.	Mol Cell	2021	https://conductscience.org/library/papers/34480848	PubMed
33,669,207	Analysis of RNA Modifications by Second- and Third-Generation Deep Sequencing: 2020 Update.	Genes (Basel)	2021	https://conductscience.org/library/papers/33669207	PubMed
33,313,824	Nucleotide resolution profiling of m3C RNA modification by HAC-seq.	Nucleic Acids Res	2021	https://conductscience.org/library/papers/33313824	PubMed
32,976,574	HydraPsiSeq: a method for systematic and quantitative mapping of pseudouridines in RNA.	Nucleic Acids Res	2020	https://conductscience.org/library/papers/32976574	PubMed
32,788,345	RNA abasic sites in yeast and human cells.	Proc Natl Acad Sci U S A	2020	https://conductscience.org/library/papers/32788345	PubMed
32,463,449	Lead-seq: transcriptome-wide structure probing in vivo using lead(II) ions.	Nucleic Acids Res	2020	https://conductscience.org/library/papers/32463449	PubMed

Show 14 more cited byShow fewer cited bySee all 445 cited by

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PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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NIH RePORTER's grant and paper linksPublic domain
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PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

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ClinicalTrials.govnone stated
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NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
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UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

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