Paper · 3785227
Characterization of a family of gamma-ray-induced CHO mutants demonstrates that the ldlA locus is diploid and encodes the low-density lipoprotein receptor.
Sege RD and 2 others. Mol Cell Biol, 1986. Cited by 32 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
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ConductScience Library. Characterization of a family of gamma-ray-induced CHO mutants demonstrates that the ldlA locus is diploid and encodes the low-density lipoprotein receptor. Papers, record 3785227. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/3785227
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Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
Topics15
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Genes | Major topic |
| Mutation | Major topic |
| Receptors, LDL | Major topic |
| Amino Acid Sequence | |
| Animals | |
| Base Sequence | |
| Cell Line | |
| Cloning, Molecular | |
| Cricetinae | |
| Cricetulus | |
| Diploidy | |
| Female | |
| Gamma Rays | |
| Ovary | |
| Plasmids |
Source PubMed
Grants0
Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.
None in this release.
Trials0
The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.
None in this release.
Comments and corrections0
PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.
None in this release.
References47
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 221,835 | Coated pits, coated vesicles, and receptor-mediated endocytosis. | Nature | 1979 | https://conductscience.org/library/papers/221835 | PubMed |
| 2 | 2,881,559 | Receptor-mediated endocytosis: concepts emerging from the LDL receptor system. | Annu Rev Cell Biol | 1985 | https://conductscience.org/library/papers/2881559 | PubMed |
| 3 | 6,155,806 | Extraction of nucleic acids from agarose gels. | Anal Biochem | 1980 | https://conductscience.org/library/papers/6155806 | PubMed |
| 4 | 6,933,469 | Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity. | Proc Natl Acad Sci U S A | 1980 | https://conductscience.org/library/papers/6933469 | PubMed |
| 5 | 6,259,625 | A system for shotgun DNA sequencing. | Nucleic Acids Res | 1981 | https://conductscience.org/library/papers/6259625 | PubMed |
| 6 | 6,266,915 | Isolation of beta-globin-related genes from a human cosmid library. | Gene | 1981 | https://conductscience.org/library/papers/6266915 | PubMed |
| 7 | 6,275,086 | Isolation of Chinese hamster cell mutants defective in the receptor-mediated endocytosis of low density lipoprotein. | J Mol Biol | 1981 | https://conductscience.org/library/papers/6275086 | PubMed |
| 8 | 6,287,224 | Direct demonstration of genetic alterations at the dihydrofolate reductase locus after gamma irradiation. | Mol Cell Biol | 1982 | https://conductscience.org/library/papers/6287224 | PubMed |
| 9 | 7,123,449 | Structural and functional hemi- and dizygous Chinese hamster chromosome 2 gene loci in CHO cells. | Somatic Cell Genet | 1982 | https://conductscience.org/library/papers/7123449 | PubMed |
| 10 | 6,295,880 | A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments. | Gene | 1982 | https://conductscience.org/library/papers/6295880 | PubMed |
1 to 10 of 47
See all 47 referencesCited by7
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 32 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 37,511,194 | Novel Tools for Comprehensive Functional Analysis of LDLR (Low-Density Lipoprotein Receptor) Variants. | Int J Mol Sci | 2023 | https://conductscience.org/library/papers/37511194 | PubMed |
| 35,022,465 | Annexin A6 and NPC1 regulate LDL-inducible cell migration and distribution of focal adhesions. | Sci Rep | 2022 | https://conductscience.org/library/papers/35022465 | PubMed |
| 10,884,919 | Expression of an LDL receptor allele with two different mutations (E256K and I402T). | Mol Pathol | 2000 | https://conductscience.org/library/papers/10884919 | PubMed |
| 2,601,697 | Isolation and characterization of an extragenic suppressor of the low-density lipoprotein receptor-deficient phenotype of a Chinese hamster ovary cell mutant. | Mol Cell Biol | 1989 | https://conductscience.org/library/papers/2601697 | PubMed |
| 2,572,508 | A molecular genetic linkage map of mouse chromosome 9 with regional localizations for the Gsta, T3g, Ets-1 and Ldlr loci. | Genetics | 1989 | https://conductscience.org/library/papers/2572508 | PubMed |
| 1,799,811 | Comparative map for mice and humans. | Mamm Genome | 1991 | https://conductscience.org/library/papers/1799811 | PubMed |
| 1,392,257 | Comparative map for mice and humans. | Mamm Genome | 1992 | https://conductscience.org/library/papers/1392257 | PubMed |
Genes0
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
None in this release.
Drugs0
The drugs whose trials, in the Pipelines release, list the paper.
None in this release.
Data1
The data bank entries PubMed's record names. Trial numbers are under Trials.
| Data bank | Accession |
|---|---|
| GENBANK | M13877 |
Source GENBANK
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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