Paper385457
Double-blind randomised clinical trial of a pepsin-inhibitory pentapeptide (pepstatin) in the treatment of duodenal ulcer.
Bonnevie O and 5 others. Gut, 1979. Cited by 16 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
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ConductScience Library. Double-blind randomised clinical trial of a pepsin-inhibitory pentapeptide (pepstatin) in the treatment of duodenal ulcer. Papers, record 385457. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/385457
Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
- Double-blind randomised clinical trial of a pepsin-inhibitory pentapeptide (pepstatin) in the treatment of duodenal ulcer.
- PubMed
Topics14
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Duodenal Ulcer | Major topic |
| Oligopeptides | Major topic |
| Pepstatins | Major topic |
| Adult | |
| Aged | |
| Clinical Trials as Topic | |
| Double-Blind Method | |
| Female | |
| Humans | |
| Length of Stay | |
| Male | |
| Middle Aged | |
| Placebos | |
| Time Factors |
Source PubMed
References15
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 14,244,036 | ANTACID THERAPY OF PEPTIC ULCER. II. AN EVALUATION OF ANTACIDS IN VITRO. | Gut | 1964 | https://conductscience.org/library/papers/14244036 | PubMed |
| 2 | 13,775,657 | Gastric proteinases in health and disease. | Gastroenterology | 1961 | https://conductscience.org/library/papers/13775657 | PubMed |
| 3 | 13,483 | Inhibition of gastric peptic activity by antacids and pepstatin. | Scand J Gastroenterol Suppl | 1976 | https://conductscience.org/library/papers/13483 | PubMed |
| 4 | 19,334 | Role of intragastric pressure, pH, and pepsin in gastric ulceration in the rat. | Gastroenterology | 1977 | https://conductscience.org/library/papers/19334 | PubMed |
| 5 | 342,360 | Double-blind controlled trial of amylopectin sulphate (Depepsen) in the symptomatic treatment of duodenal ulcer. | Gut | 1977 | https://conductscience.org/library/papers/342360 | PubMed |
| 6 | 786,772 | Effect of sodium amylosulfate (Depepsen) on the healing of duodenal ulcer. | Gastroenterology | 1976 | https://conductscience.org/library/papers/786772 | PubMed |
| 7 | 785,587 | Effect of a pepsin-inhibitory pentapeptide upon the peptic activity and acidity of gastric secretion. | Scand J Gastroenterol | 1976 | https://conductscience.org/library/papers/785587 | PubMed |
| 8 | 4,945,810 | Effect of pepstatin on acid proteases. | J Antibiot (Tokyo) | 1971 | https://conductscience.org/library/papers/4945810 | PubMed |
| 9 | 4,615,551 | The effect of amylopectin sulfate (SN-263) on the peptic activity of human gastric juice. | Acta Hepatogastroenterol (Stuttg) | 1974 | https://conductscience.org/library/papers/4615551 | PubMed |
| 10 | 4,551,010 | A trial of amylopectin sulfate (SN-263) and propantheline bromide in the long term treatment of chronic duodenal ulcer. | Gastroenterology | 1972 | https://conductscience.org/library/papers/4551010 | PubMed |
| 11 | 238,895 | Studies on the binding of amylopectin sulfate with gastric mucin. | Gastroenterology | 1975 | https://conductscience.org/library/papers/238895 | PubMed |
| 12 | 4,942,261 | Mechanism of the antipeptic action of amylopectin sulfate (SN-263), and antiulcer, mucin-like agent. | Gastroenterology | 1971 | https://conductscience.org/library/papers/4942261 | PubMed |
| 13 | 4,912,656 | A controlled study on the use of propantheline and amylopectin sulfate (SN-263) for recurrences in duodenal ulcer. | Gastroenterology | 1970 | https://conductscience.org/library/papers/4912656 | PubMed |
| 14 | 4,912,600 | Pepstatin, a new pepsin inhibitor produced by Actinomycetes. | J Antibiot (Tokyo) | 1970 | https://conductscience.org/library/papers/4912600 | PubMed |
| 15 | 4,885,393 | Specific inhibition of gastric pepsin in the treatment of gastric ulcer. | Gastroenterology | 1969 | https://conductscience.org/library/papers/4885393 | PubMed |
Cited by6
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 16 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 27,271,556 | Lysosomal protease cathepsin D; a new driver of apoptosis during acute kidney injury. | Sci Rep | 2016 | https://conductscience.org/library/papers/27271556 | PubMed |
| 22,242,022 | Reflux revisited: advancing the role of pepsin. | Int J Otolaryngol | 2012 | https://conductscience.org/library/papers/22242022 | PubMed |
| 6,107,146 | New drugs for peptic ulcer. | Br Med J | 1980 | https://conductscience.org/library/papers/6107146 | PubMed |
| 6,106,545 | Current therapy in peptic ulcer. | Drugs | 1980 | https://conductscience.org/library/papers/6106545 | PubMed |
| 3,209,115 | Prevention of acute gastric erosions in the rat by novel semi-synthetic amphipathic analogues of pepstatin. | Gut | 1988 | https://conductscience.org/library/papers/3209115 | PubMed |
| 3,045,820 | Human immunodeficiency virus has an aspartic-type protease that can be inhibited by pepstatin A. | Proc Natl Acad Sci U S A | 1988 | https://conductscience.org/library/papers/3045820 | PubMed |
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
None in this release
- Grants
- Trials
- Comments and corrections
- Genes
- Drugs
- Data
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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