ConductScience.org, home
Papers
API referenceFor AI assistants

Paper · 39708804

Mutability and hypermutation antagonize immunoglobulin codon optimality.

McGrath JJC and 16 others. Mol Cell, 2025. Cited by 4 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

Download JSON
Cite this record

ConductScience Library. Mutability and hypermutation antagonize immunoglobulin codon optimality. Papers, record 39708804. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/39708804

On this page

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Mutability and hypermutation antagonize immunoglobulin codon optimality.
PubMed
Journal
Mol Cell
PubMed
Year
2025
PubMed
Publication types
Journal Article, Research Support, N.I.H., Extramural
PubMed
Citations, by iCite
4
iCite
Revised in PubMed
2026-10-08
PubMed

Authors17

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1McGrath JJCJoshua J C
2Park JJuyeon
3Troxell CAChloe A
4Chervin JCJordan C
5Li LLei
6Kent JRJohnathan R
7Changrob SSiriruk
8Fu YYanbin
9Huang MMin
10Zheng NYNai-Ying

1 to 10 of 17Source PubMed

See all 17 authors

Topics16

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Somatic Hypermutation, ImmunoglobulinMajor topic
CodonMajor topic
MutationMajor topic
Animals
Humans
Mice
SARS-CoV-2
Immunoglobulin Variable Region
Zebrafish
Antibodies, Monoclonal
Immunoglobulin Heavy Chains
COVID-19
V(D)J Recombination
Immunoglobulin G
HIV-1
Complementarity Determining Regions

Source PubMed

Grants9

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
U19 AI168632NIAID NIH HHSUnited StatesU19AI168632PubMed and NIHNIH RePORTER
P01 CA272295NCI NIH HHSUnited StatesP01CA272295PubMedNIH RePORTER
U01 AI153700NIAID NIH HHSUnited StatesU01AI153700PubMed and NIHNIH RePORTER
75N93019C00051NIAID NIH HHSUnited StatesPubMedPubMed
U01 AI165452NIAID NIH HHSUnited StatesU01AI165452PubMed and NIHNIH RePORTER
INV-004956Gates FoundationUnited StatesPubMedPubMed
U01 AI144616NIAID NIH HHSUnited StatesU01AI144616PubMed and NIHNIH RePORTER
P01 AI165077NIAID NIH HHSUnited StatesP01AI165077PubMed and NIHNIH RePORTER
75N93021C00014NIAID NIH HHSUnited StatesPubMedPubMed

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References73

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
130,539,468An Efficient Method to Generate Monoclonal Antibodies from Human B Cells.Methods Mol Biol2019https://conductscience.org/library/papers/30539468PubMed
219,423,829High-throughput sequencing of the zebrafish antibody repertoire.Science2009https://conductscience.org/library/papers/19423829PubMed
316,151,406Engineered antibody fragments and the rise of single domains.Nat Biotechnol2005https://conductscience.org/library/papers/16151406PubMed
421,471,456Alternative mechanisms of receptor editing in autoreactive B cells.Proc Natl Acad Sci U S A2011https://conductscience.org/library/papers/21471456PubMed
536,862,518Site of vulnerability on SARS-CoV-2 spike induces broadly protective antibody against antigenically distinct Omicron subvariants.J Clin Invest2023https://conductscience.org/library/papers/36862518PubMed
616,083,957Similarity and divergence in the development and expression of the mouse and human antibody repertoires.Dev Comp Immunol2006https://conductscience.org/library/papers/16083957PubMed
78,459,227Receptor editing: an approach by autoreactive B cells to escape tolerance.J Exp Med1993https://conductscience.org/library/papers/8459227PubMed
81,910,677Avian B-cell development: generation of an immunoglobulin repertoire by gene conversion.Annu Rev Immunol1991https://conductscience.org/library/papers/1910677PubMed
934,875,068IMGT® databases, related tools and web resources through three main axes of research and development.Nucleic Acids Res2022https://conductscience.org/library/papers/34875068PubMed
1039,667,375
Molecular features of the serological IgG repertoire elicited by egg-based, cell-based, or recombinant haemagglutinin-based seasonal influenza vaccines: a comparative, prospective, observational cohort study.
Lancet Microbe2025https://conductscience.org/library/papers/39667375PubMed

1 to 10 of 73

See all 73 references

Cited by4

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 4 citations.

PMIDTitleJournalYearIn PapersSource
42,134,788Highlights of 2025: advances in germinal centers.Immunol Cell Biol2026https://conductscience.org/library/papers/42134788PubMed
40,301,716Immunoglobulin gene loci structure and diversity of raccoon dog (Nyctereutes procyonoides).BMC Genomics2025https://conductscience.org/library/papers/40301716PubMed
40,155,920Molecular characterization and complexity of the immunoglobulin repertoire in the silver-black fox (Vulpes vulpes).BMC Vet Res2025https://conductscience.org/library/papers/40155920PubMed
39,563,034Structure and sequence engineering approaches to improve in vivo expression of nucleic acid-delivered antibodies.Mol Ther2025https://conductscience.org/library/papers/39563034PubMed

Genes1

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn Genes
IGH3,492PubTator's text mininghttps://conductscience.org/library/genes/3492

Source NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this paper from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/papers/v1/39708804

GET https://conductscience.org/api/papers/v1/39708804/references?page=2

API referenceFor AI assistants