Paper · 40114969

A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.

Le T and 13 others. Front Cell Dev Biol, 2025. Cited by 1 paper, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression. Papers, record 40114969. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/40114969

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Paper

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Title: A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.; PubMed
Journal: Front Cell Dev Biol; PubMed
Year: 2025; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/40114969/; PubMed
DOI: https://doi.org/10.3389/fcell.2025.1522094; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC11922885/; PubMed
The journal: https://conductscience.org/library/journal-index/101630250; PubMed
Citations, by iCite: 1; iCite
Revised in PubMed: 2025-07-21; PubMed

Authors14

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Le T	Tien
2	Htun S	Stephanie
3	Pandey MK	Manoj Kumar
4	Sun Y	Yihui
5	Magnusen AF	Albert Frank
6	Ullah E	Ehsan
7	Lauzon J	Julie
8	Beres S	Shannon
9	Lee C	Chung
10	Guan B	Bin

1 to 10 of 14Source PubMed

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Topics0

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None in this release.

Grants4

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes it	Agency	Country	NIH project	Stated by	Source
R01 EY032976	NEI NIH HHS	United States	R01EY032976	PubMed and NIH	NIH RePORTER
R01 EY035500	NEI NIH HHS	United States	R01EY035500	PubMed and NIH	NIH RePORTER
			ZIAEY000469	NIH	NIH RePORTER
			ZIAEY000564	NIH	NIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References63

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	31,479,653	Molecular characterization of the human lens epithelium-derived cell line SRA01/04.	Exp Eye Res	2019	https://conductscience.org/library/papers/31479653	PubMed
2	6,545,385	Colobomatous macrophthalmia with microcornea.	Ophthalmic Paediatr Genet	1984	https://conductscience.org/library/papers/6545385	PubMed
3	9,640,329	Disregulation of ocular morphogenesis by lens-specific expression of FGF-3/int-2 in transgenic mice.	Dev Biol	1998	https://conductscience.org/library/papers/9640329	PubMed
4	2,632,221	Fibroblast growth factor (FGF) induces different responses in lens epithelial cells depending on its concentration.	Development	1989	https://conductscience.org/library/papers/2632221	PubMed
5	27,325,740	Overexpression of eIF5 or its protein mimic 5MP perturbs eIF2 function and induces ATF4 translation through delayed re-initiation.	Nucleic Acids Res	2016	https://conductscience.org/library/papers/27325740	PubMed
6	31,776,724	Crim1C140S mutant mice reveal the importance of cysteine 140 in the internal region 1 of CRIM1 for its physiological functions.	Mamm Genome	2019	https://conductscience.org/library/papers/31776724	PubMed
7	17,460,146	Crim1KST264/KST264 mice implicate Crim1 in the regulation of vascular endothelial growth factor-A activity during glomerular vascular development.	J Am Soc Nephrol	2007	https://conductscience.org/library/papers/17460146	PubMed
8	12,464,430	CRIM1 is involved in endothelial cell capillary formation in vitro and is expressed in blood vessels in vivo.	Mech Dev	2002	https://conductscience.org/library/papers/12464430	PubMed
9	29,700,225	Single-cell reconstruction of developmental trajectories during zebrafish embryogenesis.	Science	2018	https://conductscience.org/library/papers/29700225	PubMed
10	37,995,681	Single-cell analysis of shared signatures and transcriptional diversity during zebrafish development.	Dev Cell	2023	https://conductscience.org/library/papers/37995681	PubMed

1 to 10 of 63

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Cited by1

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 1 citation.

PMID	Title	Journal	Year	In Papers
41,332,767	Parallel and non-parallel features of adaptive radiation in Yucatán pupfishes.	bioRxiv	2025	https://conductscience.org/library/papers/41332767

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Genes0

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None in this release.

Drugs0

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None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

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PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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