Paper40360992
Nonlinear association between AST/ALT ratio and 28-day all-cause mortality following ICU admission in critically ill cirrhotic patients: a retrospective cohort study.
Xu Z and 1 other. BMC Gastroenterol, 2025. Cited by 3 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
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ConductScience Library. Nonlinear association between AST/ALT ratio and 28-day all-cause mortality following ICU admission in critically ill cirrhotic patients: a retrospective cohort study. Papers, record 40360992. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/40360992
Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
- Nonlinear association between AST/ALT ratio and 28-day all-cause mortality following ICU admission in critically ill cirrhotic patients: a retrospective cohort study.
- PubMed
Topics14
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Liver Cirrhosis | Major topic |
| Intensive Care Units | Major topic |
| Aspartate Aminotransferases | Major topic |
| Alanine Transaminase | Major topic |
| Humans | |
| Male | |
| Retrospective Studies | |
| Middle Aged | |
| Female | |
| Critical Illness | |
| Aged | |
| Biomarkers | |
| Hospital Mortality | |
| Nonlinear Dynamics |
Source PubMed
References50
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 36,652,959 | Cirrhosis Management in the Intensive Care Unit. | Semin Liver Dis | 2023 | https://conductscience.org/library/papers/36652959 | PubMed |
| 2 | 35,985,502 | Prognostic value of De Ritis ratio in patients with acute myocardial infarction. | Clin Chim Acta | 2022 | https://conductscience.org/library/papers/35985502 | PubMed |
| 3 | 21,893,129 | Muscle wasting is associated with mortality in patients with cirrhosis. | Clin Gastroenterol Hepatol | 2012 | https://conductscience.org/library/papers/21893129 | PubMed |
| 4 | 22,713,601 | Fructose-rich diet leads to reduced aerobic capacity and to liver injury in rats. | Lipids Health Dis | 2012 | https://conductscience.org/library/papers/22713601 | PubMed |
| 5 | 38,576,715 | Association of AST/ALT ratio with 90-day outcomes in patients with acute exacerbation of chronic liver disease: a prospective multicenter cohort study in China. | Front Med (Lausanne) | 2024 | https://conductscience.org/library/papers/38576715 | PubMed |
| 6 | 36,759,386 | Baseline ALBI Grade Predicts Benefits After Splenectomy for Cirrhotic Patients with Hypersplenism. | J Gastrointest Surg | 2023 | https://conductscience.org/library/papers/36759386 | PubMed |
| 7 | 34,397,804 | The association between AST/ALT ratio and all-cause and cardiovascular mortality in patients with hypertension. | Medicine (Baltimore) | 2021 | https://conductscience.org/library/papers/34397804 | PubMed |
| 8 | 37,639,845 | Role of inflammasomes and cytokines in immune dysfunction of liver cirrhosis. | Cytokine | 2023 | https://conductscience.org/library/papers/37639845 | PubMed |
| 9 | 23,474,284 | Acute-on-chronic liver failure is a distinct syndrome that develops in patients with acute decompensation of cirrhosis. | Gastroenterology | 2013 | https://conductscience.org/library/papers/23474284 | PubMed |
| 10 | 34,667,893 | EEG abnormality as a prognostic factor in cirrhotic patients with Grade III-IV hepatic encephalopathy requiring mechanical ventilation: A retrospective analysis. | J Clin Transl Res | 2021 | https://conductscience.org/library/papers/34667893 | PubMed |
| 11 | 36,592,292 | Spleen stiffness: a predictive factor of dismal prognosis in liver cirrhosis. | Clin J Gastroenterol | 2023 | https://conductscience.org/library/papers/36592292 | PubMed |
| 12 | 34,869,425 | Hyperoxia Provokes Time- and Dose-Dependent Gut Injury and Endotoxemia and Alters Gut Microbiome and Transcriptome in Mice. | Front Med (Lausanne) | 2021 | https://conductscience.org/library/papers/34869425 | PubMed |
| 13 | 32,459,924 | Acute-on-Chronic Liver Failure. | N Engl J Med | 2020 | https://conductscience.org/library/papers/32459924 | PubMed |
| 14 | 35,522,396 | Management of Liver Decompensation in Advanced Liver Disease (Renal Impairment, Liver Failure, Adrenal Insufficiency, Cardiopulmonary Complications). | Clin Drug Investig | 2022 | https://conductscience.org/library/papers/35522396 | PubMed |
| 15 | 32,039,351 | Acute-on-chronic liver failure: Objective admission and support criteria in the intensive care unit. | JHEP Rep | 2019 | https://conductscience.org/library/papers/32039351 | PubMed |
| 16 | 32,280,697 | Fluid Biomarkers for Predicting the Prognosis of Liver Cirrhosis. | Biomed Res Int | 2020 | https://conductscience.org/library/papers/32280697 | PubMed |
| 17 | 38,727,511 | Global burden of liver cirrhosis 1990-2019 and 20 years forecast: results from the global burden of disease study 2019. | Ann Med | 2024 | https://conductscience.org/library/papers/38727511 | PubMed |
| 18 | 30,560,047 | Mechanisms of Inflammatory Liver Injury and Drug-Induced Hepatotoxicity. | Curr Pharmacol Rep | 2018 | https://conductscience.org/library/papers/30560047 | PubMed |
| 19 | 34,522,109 | The Association of Aspartate Aminotransferase/Alanine Aminotransferase Ratio with Diabetic Nephropathy in Patients with Type 2 Diabetes. | Diabetes Metab Syndr Obes | 2021 | https://conductscience.org/library/papers/34522109 | PubMed |
| 20 | 30,266,282 | Burden of liver diseases in the world. | J Hepatol | 2019 | https://conductscience.org/library/papers/30266282 | PubMed |
Cited by3
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 3 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 41,519,991 | Integration of 12-h time-restricted feeding with exercise training potentiates weight loss and attenuates MASLD in diet-induced obese mice. | Sci Rep | 2026 | https://conductscience.org/library/papers/41519991 | PubMed |
| 41,089,541 | Clinical Value of APRI and FIB-4 on Bleeding Risk and 30-Day Prognosis in Patients with Liver Cirrhosis Complicated with Esophagogastric Varices. | Int J Gen Med | 2025 | https://conductscience.org/library/papers/41089541 | PubMed |
| 40,722,522 | Prognostic Value of the AST/ALT Ratio in Patients with Septic Shock: A Prospective, Multicenter, Registry-Based Observational Study. | Diagnostics (Basel) | 2025 | https://conductscience.org/library/papers/40722522 | PubMed |
Genes1
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes |
|---|---|---|---|
| SLC17A5 | 26,503 | PubTator's text mining | https://conductscience.org/library/genes/26503 |
Source NCBI Gene
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
None in this release
- Grants
- Trials
- Comments and corrections
- Drugs
- Data
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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