Paper4060

Creatine kinase equilibrium and lactate content compared with muscle pH in tissue samples obtained after isometric exercise.

Sahlin K and 2 others. Biochem J, 1975. Cited by 190 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

Cite this record

ConductScience Library. Creatine kinase equilibrium and lactate content compared with muscle pH in tissue samples obtained after isometric exercise. Papers, record 4060. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/4060

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Creatine kinase equilibrium and lactate content compared with muscle pH in tissue samples obtained after isometric exercise.; PubMed
Journal: Biochem J; PubMed
Year: 1975; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/4060/; PubMed
DOI: https://doi.org/10.1042/bj1520173; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC1172458/; PubMed
The journal: https://conductscience.org/library/journal-index/2984726R; PubMed
Citations, by iCite: 190; iCite
Relative citation ratio, by iCite: 7.67; iCite
Revised in PubMed: 2019-05-01; PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Sahlin K	K
2	Harris RC	R C
3	Hultman E	E

Source PubMed

Topics15

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Creatine Kinase	Major topic
Lactates	Major topic
Muscles	Major topic
Physical Exertion	Major topic
Adenosine Diphosphate
Adenosine Monophosphate
Adenosine Triphosphate
Creatine
Humans
Hydrogen-Ion Concentration
Kinetics
Magnesium
Male
Muscle Contraction
Pyruvates

Source PubMed

Show 9 more topicsShow fewer topics

References16

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	1,129,596	The effect of circulatory occlusion on isometric exercise capacity and energy metabolism of the quadriceps muscle in man.	Scand J Clin Lab Invest	1975	https://conductscience.org/library/papers/1129596	PubMed
4	13,807,760	The creatine phosphoryltransfer reaction in iodoacetate-poisoned muscle.	J Gen Physiol	1959	https://conductscience.org/library/papers/13807760	PubMed
5	13,908,259	Studies on the creatine kinase equilibrium in muscle and the significance of ATP and ADP levels.	Biochem Biophys Res Commun	1962	https://conductscience.org/library/papers/13908259	PubMed
6	13,988,021	The amount and compartmentalization of adenosine diphosphate in muscle.	Biochim Biophys Acta	1962	https://conductscience.org/library/papers/13988021	PubMed
7	14,479,743	Kinetic properties and equilibrium constant of the adenosine triphosphate-creatine transphosphorylase-catalyzed reaction.	J Biol Chem	1961	https://conductscience.org/library/papers/14479743	PubMed
10	4,640,620	Intracellular pH of the brain in arterial hypoxemia, evaluated with the CO 2 method and from the creatine phosphokinase equilibrium.	Scand J Clin Lab Invest	1972	https://conductscience.org/library/papers/4640620	PubMed
11	4,686,748	[Restitution of the energy metabolism of rat skeletal muscles following long lasting ischemia].	Res Exp Med (Berl)	1973	https://conductscience.org/library/papers/4686748	PubMed
12	4,718,747	The concentrations of free and bound magnesium in rat tissues. Relative constancy of free Mg 2+ concentrations.	J Biol Chem	1973	https://conductscience.org/library/papers/4718747	PubMed
13	4,852,173	Glycogen, glycolytic intermediates and high-energy phosphates determined in biopsy samples of musculus quadriceps femoris of man at rest. Methods and variance of values.	Scand J Clin Lab Invest	1974	https://conductscience.org/library/papers/4852173	PubMed
14	5,010,039	Blood and muscle pH after maximal exercise in man.	J Appl Physiol	1972	https://conductscience.org/library/papers/5010039	PubMed
15	5,054,429	Muscle metabolism during isometric exercise performed at constant force.	J Appl Physiol	1972	https://conductscience.org/library/papers/5054429	PubMed
16	5,086,239	The effect of hypercapnia upon intracellular pH in the brain, evaluated by the bicarbonate-carbonic acid method and from the creatine phosphokinase equilibrium.	J Neurochem	1972	https://conductscience.org/library/papers/5086239	PubMed
17	5,220,297	Intracellular pH--true parameter or misnomer?	Ann N Y Acad Sci	1966	https://conductscience.org/library/papers/5220297	PubMed
18	5,246,543	The state of magnesium in cells as estimated from the adenylate kinase equilibrium.	Proc Natl Acad Sci U S A	1968	https://conductscience.org/library/papers/5246543	PubMed
19	5,538,778	Carbohydrate metabolism and electrolyte changes in human muscle tissue during heavy work.	J Appl Physiol	1971	https://conductscience.org/library/papers/5538778	PubMed
20	6,060,444	Post-mortem glycolysis in ox skeletal muscle. Effect of temperature on the concentrations of glycolytic intermediates and cofactors.	Biochem J	1967	https://conductscience.org/library/papers/6060444	PubMed

Show 10 more referencesShow fewer references

Cited by43

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 190 citations.

PMID	Title	Journal	Year	In Papers	Source
42,653,113	Activation of ATP Consumption Is Necessary to Stimulate Glycogenolysis in Skeletal Muscle.	Int J Mol Sci	2026	https://conductscience.org/library/papers/42653113	PubMed
41,828,697	The Critical Role of Adenylate Kinase in Regulating the Glycolysis Rate in Cells.	Int J Mol Sci	2026	https://conductscience.org/library/papers/41828697	PubMed
40,993,887	Comment on "A 10-Year Longitudinal Study of Muscle Morphology and Performance in Masters Sprinters" by Hendrickse et al. - the authors reply.	J Cachexia Sarcopenia Muscle	2025	https://conductscience.org/library/papers/40993887	PubMed
40,088,272	Lactic acidosis: implications for human exercise performance.	Eur J Appl Physiol	2025	https://conductscience.org/library/papers/40088272	PubMed
39,964,101	The birth of modern sports nutrition: tracing the path from muscle biopsies to creatine supplementation-A narrative review.	J Int Soc Sports Nutr	2025	https://conductscience.org/library/papers/39964101	PubMed
39,771,003	Acute Co-Ingestion of Caffeine and Sodium Bicarbonate on Muscular Endurance Performance.	Nutrients	2024	https://conductscience.org/library/papers/39771003	PubMed
38,404,749	Acute effects of sodium citrate supplementation on competitive performance and lactate level of elite fitness challenge athletes: A crossover, placebo-controlled, double-blind study.	J Exerc Sci Fit	2024	https://conductscience.org/library/papers/38404749	PubMed
38,214,271	Exercise Training Decreases Nitrite Concentration in the Heart and Locomotory Muscles of Rats Without Changing the Muscle Nitrate Content.	J Am Heart Assoc	2024	https://conductscience.org/library/papers/38214271	PubMed
38,104,212	Evidence of an intracellular creatine-sensing mechanism that modulates creatine biosynthesis via AGAT expression in human HAP1 cells.	Sci Rep	2023	https://conductscience.org/library/papers/38104212	PubMed
37,151,086	Supplementation of caffeine and sodium bicarbonate together could not improve performance and performance-related factors in CrossFit participants: a randomized, double-blind, placebo-controlled study.	J Int Soc Sports Nutr	2023	https://conductscience.org/library/papers/37151086	PubMed
35,355,125	A century of exercise physiology: key concepts in regulation of glycogen metabolism in skeletal muscle.	Eur J Appl Physiol	2022	https://conductscience.org/library/papers/35355125	PubMed
32,431,619	Exhaustion of Skeletal Muscle Fibers Within Seconds: Incorporating Phosphate Kinetics Into a Hill-Type Model.	Front Physiol	2020	https://conductscience.org/library/papers/32431619	PubMed
32,024,038	Supplements and Nutritional Interventions to Augment High-Intensity Interval Training Physiological and Performance Adaptations-A Narrative Review.	Nutrients	2020	https://conductscience.org/library/papers/32024038	PubMed
31,623,659	Caffeine and sodium bicarbonate supplementation alone or together improve karate performance.	J Int Soc Sports Nutr	2019	https://conductscience.org/library/papers/31623659	PubMed
29,868,599	Time to Optimize Supplementation: Modifying Factors Influencing the Individual Responses to Extracellular Buffering Agents.	Front Nutr	2018	https://conductscience.org/library/papers/29868599	PubMed
29,771,966	The effect of chronic progressive-dose sodium bicarbonate ingestion on CrossFit-like performance: A double-blind, randomized cross-over trial.	PLoS One	2018	https://conductscience.org/library/papers/29771966	PubMed
26,553,493	Nutritional Strategies to Modulate Intracellular and Extracellular Buffering Capacity During High-Intensity Exercise.	Sports Med	2015	https://conductscience.org/library/papers/26553493	PubMed
26,250,346	What limits performance during whole-body incremental exercise to exhaustion in humans?	J Physiol	2015	https://conductscience.org/library/papers/26250346	PubMed
22,808,209	Energy metabolism during repeated sets of leg press exercise leading to failure or not.	PLoS One	2012	https://conductscience.org/library/papers/22808209	PubMed
20,976,067	Anaerobic energy expenditure and mechanical efficiency during exhaustive leg press exercise.	PLoS One	2010	https://conductscience.org/library/papers/20976067	PubMed

Show 14 more cited byShow fewer cited bySee all 43 cited by

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PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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NIH RePORTER's grant and paper linksPublic domain
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PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

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NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
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