Paper40870

Differential elution of Clq, Clr and Cls from human Cl bound to immune aggregates. Use in the rapid purification of Cl subcomponents.

Arlaud GJ and 3 others. Mol Immunol, 1979. Cited by 141 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Differential elution of Clq, Clr and Cls from human Cl bound to immune aggregates. Use in the rapid purification of Cl subcomponents. Papers, record 40870. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/40870

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Differential elution of Clq, Clr and Cls from human Cl bound to immune aggregates. Use in the rapid purification of Cl subcomponents.; PubMed
Journal: Mol Immunol; PubMed
Year: 1979; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/40870/; PubMed
DOI: https://doi.org/10.1016/0161-5890(79)90069-5; PubMed
The journal: https://conductscience.org/library/journal-index/7905289; PubMed
Citations, by iCite: 141; iCite
Relative citation ratio, by iCite: 3.55; iCite
Revised in PubMed: 2019-08-23; PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Arlaud GJ	G J
2	Sim RB	R B
3	Duplaa AM	A M
4	Colomb MG	M G

Source PubMed

Topics9

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Complement C1	Major topic
Complement Pathway, Classical
Electrophoresis, Polyacrylamide Gel
Humans
Hydrogen-Ion Concentration
Immunoglobulin G
Osmolar Concentration
Ovalbumin
Protein Binding

Source PubMed

Show 3 more topicsShow fewer topics

Cited by51

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 141 citations.

PMID	Title	Journal	Year	In Papers	Source
41,176,693	The fc fragment of IgMs binds C1q to activate the first step of the classical complement pathway, while inhibiting complement-dependent cytotoxicity.	FEBS J	2026	https://conductscience.org/library/papers/41176693	PubMed
38,911,852	Revisiting the interaction between complement lectin pathway protease MASP-2 and SARS-CoV-2 nucleoprotein.	Front Immunol	2024	https://conductscience.org/library/papers/38911852	PubMed
35,685,087	Biophysical Characterization of the Oligomeric States of Recombinant Immunoglobulins Type-M and Their C1q-Binding Kinetics by Biolayer Interferometry.	Front Bioeng Biotechnol	2022	https://conductscience.org/library/papers/35685087	PubMed
34,066,122	Molecular Basis of Complement C1q Collagen-Like Region Interaction with the Immunoglobulin-Like Receptor LAIR-1.	Int J Mol Sci	2021	https://conductscience.org/library/papers/34066122	PubMed
33,193,398	Complement C1q Interacts With LRP1 Clusters II and IV Through a Site Close but Different From the Binding Site of Its C1r and C1s-Associated Proteases.	Front Immunol	2020	https://conductscience.org/library/papers/33193398	PubMed
32,296,440	Molecular and Cellular Interactions of Scavenger Receptor SR-F1 With Complement C1q Provide Insights Into Its Role in the Clearance of Apoptotic Cells.	Front Immunol	2020	https://conductscience.org/library/papers/32296440	PubMed
32,163,462	Transient pentameric IgM fulfill biological function-Effect of expression host and transfection on IgM properties.	PLoS One	2020	https://conductscience.org/library/papers/32163462	PubMed
31,749,804	C1R Mutations Trigger Constitutive Complement 1 Activation in Periodontal Ehlers-Danlos Syndrome.	Front Immunol	2019	https://conductscience.org/library/papers/31749804	PubMed
30,923,526	Interaction of C1q With Pentraxin 3 and IgM Revisited: Mutational Studies With Recombinant C1q Variants.	Front Immunol	2019	https://conductscience.org/library/papers/30923526	PubMed
29,563,915	C1q and Mannose-Binding Lectin Interact with CR1 in the Same Region on CCP24-25 Modules.	Front Immunol	2018	https://conductscience.org/library/papers/29563915	PubMed
29,209,066	Interaction of Complement Defence Collagens C1q and Mannose-Binding Lectin with BMP-1/Tolloid-like Proteinases.	Sci Rep	2017	https://conductscience.org/library/papers/29209066	PubMed
26,973,654	Structural and Functional Characterization of a Single-Chain Form of the Recognition Domain of Complement Protein C1q.	Front Immunol	2016	https://conductscience.org/library/papers/26973654	PubMed
23,861,840	The serine protease domain of MASP-3: enzymatic properties and crystal structure in complex with ecotin.	PLoS One	2013	https://conductscience.org/library/papers/23861840	PubMed
23,650,384	Expression of recombinant human complement C1q allows identification of the C1r/C1s-binding sites.	Proc Natl Acad Sci U S A	2013	https://conductscience.org/library/papers/23650384	PubMed
20,727,163	Recombinant human complement component C2 produced in a human cell line restores the classical complement pathway activity in-vitro: an alternative treatment for C2 deficiency diseases.	BMC Immunol	2010	https://conductscience.org/library/papers/20727163	PubMed
20,592,021	Mapping surface accessibility of the C1r/C1s tetramer by chemical modification and mass spectrometry provides new insights into assembly of the human C1 complex.	J Biol Chem	2010	https://conductscience.org/library/papers/20592021	PubMed
20,410,306	Complement protein C1q forms a complex with cytotoxic prion protein oligomers.	J Biol Chem	2010	https://conductscience.org/library/papers/20410306	PubMed
20,008,834	Analysis of human C1q by combined bottom-up and top-down mass spectrometry: detailed mapping of post-translational modifications and insights into the C1r/C1s binding sites.	Mol Cell Proteomics	2010	https://conductscience.org/library/papers/20008834	PubMed
19,494,295	Analogous interactions in initiating complexes of the classical and lectin pathways of complement.	J Immunol	2009	https://conductscience.org/library/papers/19494295	PubMed
19,473,974	Identification of the C1q-binding Sites of Human C1r and C1s: a refined three-dimensional model of the C1 complex of complement.	J Biol Chem	2009	https://conductscience.org/library/papers/19473974	PubMed

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PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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ClinicalTrials.govNo license stated
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NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

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ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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