Paper · 40892829

Conservation and divergence of ciprofloxacin persister survival mechanisms between Pseudomonas aeruginosa and Escherichia coli.

Leon G and 1 other. PLoS Genet, 2025. Cited by 4 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Conservation and divergence of ciprofloxacin persister survival mechanisms between Pseudomonas aeruginosa and Escherichia coli. Papers, record 40892829. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/40892829

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Conservation and divergence of ciprofloxacin persister survival mechanisms between Pseudomonas aeruginosa and Escherichia coli.; PubMed
Journal: PLoS Genet; PubMed
Year: 2025; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/40892829/; PubMed
DOI: https://doi.org/10.1371/journal.pgen.1011840; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC12413089/; PubMed
The journal: https://conductscience.org/library/journal-index/101239074; PubMed
Citations, by iCite: 4; iCite
Revised in PubMed: 2025-09-08; PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Leon G	Gabrielle		https://orcid.org/0009-0005-0912-5795
2	Brynildsen MP	Mark P		https://orcid.org/0000-0001-5707-8894

Source PubMed

Topics13

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Pseudomonas aeruginosa	Major topic
Ciprofloxacin	Major topic
Escherichia coli	Major topic
SOS Response, Genetics
Anti-Bacterial Agents
Humans
DNA Damage
Pseudomonas Infections
Drug Resistance, Bacterial
Homologous Recombination
DNA Repair
Cystic Fibrosis
DNA End-Joining Repair

Source PubMed

Grants2

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes it	Agency	Country	NIH project	Stated by	Source
R21 AI182745	NIAID NIH HHS	United States	R21AI182745	PubMed and NIH	NIH RePORTER
R21 AI185486	NIAID NIH HHS	United States	R21AI185486	PubMed and NIH	NIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References74

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	27,105,118	Enhanced Efflux Activity Facilitates Drug Tolerance in Dormant Bacterial Cells.	Mol Cell	2016	https://conductscience.org/library/papers/27105118	PubMed
2	39,374,386	Tracking the progeny of bacterial persisters using a CRISPR-based genomic recorder.	Proc Natl Acad Sci U S A	2024	https://conductscience.org/library/papers/39374386	PubMed
3	30,980,069	Definitions and guidelines for research on antibiotic persistence.	Nat Rev Microbiol	2019	https://conductscience.org/library/papers/30980069	PubMed
4	34,097,492	The AcrAB-TolC Efflux Pump Impacts Persistence and Resistance Development in Stationary-Phase Escherichia coli following Delafloxacin Treatment.	Antimicrob Agents Chemother	2021	https://conductscience.org/library/papers/34097492	PubMed
5	20,616,014	Structure of bacterial LigD 3'-phosphoesterase unveils a DNA repair superfamily.	Proc Natl Acad Sci U S A	2010	https://conductscience.org/library/papers/20616014	PubMed
6	38,564,687	Differential impacts of DNA repair machinery on fluoroquinolone persisters with different chromosome abundances.	mBio	2024	https://conductscience.org/library/papers/38564687	PubMed
7	160,562	Identification of the lexA gene product of Escherichia coli K-12.	Proc Natl Acad Sci U S A	1979	https://conductscience.org/library/papers/160562	PubMed
8	9,293,187	DNA gyrase, topoisomerase IV, and the 4-quinolones.	Microbiol Mol Biol Rev	1997	https://conductscience.org/library/papers/9293187	PubMed
9	11,445,083	Identification of bacterial homologues of the Ku DNA repair proteins.	FEBS Lett	2001	https://conductscience.org/library/papers/11445083	PubMed
10	30,647,458	Bacterial persistence promotes the evolution of antibiotic resistance by increasing survival and mutation rates.	ISME J	2019	https://conductscience.org/library/papers/30647458	PubMed

1 to 10 of 74

See all 74 references

Cited by4

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 4 citations.

PMID	Title	Journal	Year	In Papers	Source
42,766,644	Genetic analysis of epistasis between nucleotide excision repair and homologous recombination in the recovery of persisters after fluoroquinolone treatment.	PLoS Genet	2026	https://conductscience.org/library/papers/42766644	PubMed
42,489,447	Contributions of persisters and the Eagle effect to survival of Yersinia pseudotuberculosis under clinical antimicrobials.	Microbiol Spectr	2026	https://conductscience.org/library/papers/42489447	PubMed
42,306,942	Non-canonical double-stranded DNA break repair in Pseudomonas aeruginosa includes LigD-independent non-homologous end joining.	Nucleic Acids Res	2026	https://conductscience.org/library/papers/42306942	PubMed
41,400,384	Stationary-phase Pseudomonas aeruginosa fluoroquinolone persisters mostly avoid DNA double-stranded breaks.	mSphere	2026	https://conductscience.org/library/papers/41400384	PubMed

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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