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Paper4100303

Studies on the mechanism of endogenous pyrogen production. I. Investigation of new protein synthesis in stimulated human blood leucocytes.

Bodel P. Yale J Biol Med, 1970. Cited by 42 papers, by iCite.

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ConductScience Library. Studies on the mechanism of endogenous pyrogen production. I. Investigation of new protein synthesis in stimulated human blood leucocytes. Papers, record 4100303. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/4100303

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Studies on the mechanism of endogenous pyrogen production. I. Investigation of new protein synthesis in stimulated human blood leucocytes.
PubMed
Journal
Yale J Biol Med
PubMed
Year
1970
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
42
iCite
Relative citation ratio, by iCite
1.32
iCite
Revised in PubMed
2018-11-13
PubMed

Authors1

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Bodel PP

Source PubMed

Topics5

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Animals
Centrifugation
Dactinomycin
Dextrans
Dialysis

Source PubMed

References22

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
114,453,158Studies on the pathogenesis of fever. X. The effect of certain enzyme inhibitors on the production and activity of leucocvtic pvrogen.J Exp Med1962https://conductscience.org/library/papers/14453158PubMed
25,937,057Studies on the pathogenesis of fever. XIV. Further observations on the chemistry of leukocytic pyrogen.J Exp Med1966https://conductscience.org/library/papers/5937057PubMed
34,185,168Release of histamine and lysosomal enzymes by human leukocytes during phagocytosis of staphylococci.J Lab Clin Med1969https://conductscience.org/library/papers/4185168PubMed
44,902,892Studies on the pathogenesis of fever. 18. Activation of leukocytes for pyrogen production.J Exp Med1970https://conductscience.org/library/papers/4902892PubMed
513,652,121Metabolism of human leukocytes in vitro. II. The effect of several agents on the incorporation of radioactive formate and glycine.Cancer Res1959https://conductscience.org/library/papers/13652121PubMed
614,159,044STUDIES ON THE PATHOGENESIS OF FEVER. XII. ELECTROLYTIC FACTORYS INFLUENCING THE RELEASE OF ENDOGENOUS PYROGEN FROM POLYMORPHONUCLEAR LEUKOCYTES.J Exp Med1964https://conductscience.org/library/papers/14159044PubMed
85,935,620Human leukocyte pyrogen producing fever in rabbits.Proc Soc Exp Biol Med1966https://conductscience.org/library/papers/5935620PubMed
104,874,495Ultrastructure of human leukocytes after simultaneous fixation with glutaraldehyde and osmium tetroxide and "postfixation" in uranyl acetate.J Cell Biol1968https://conductscience.org/library/papers/4874495PubMed
115,409,945Studies on the pathogenesis of fever. XVII. The cationic control of pyrogen release from exudate granulocytes in vitro.J Exp Med1970https://conductscience.org/library/papers/5409945PubMed
1214,454,025Metabolic basis of phagocytic activity.Physiol Rev1962https://conductscience.org/library/papers/14454025PubMed
136,079,946Effect of inhibitors of protein synthesis on pyrogen production by granulocytes.Proc Soc Exp Biol Med1967https://conductscience.org/library/papers/6079946PubMed
146,062,001Quantitative aspects of the release of leukocyte pyrogen from rabbit blood incubated with endotoxin.J Exp Med1967https://conductscience.org/library/papers/6062001PubMed
155,343,431Species specificity of leukocytic pyrogens.J Exp Med1969https://conductscience.org/library/papers/5343431PubMed
165,780,691Comparison of endogenous pyrogens from human and rabbit leucocytes utilizing Sephadex filtration.Yale J Biol Med1969https://conductscience.org/library/papers/5780691PubMed
175,635,382Studies on the pathogenesis of fever. XVI. Purification and further chemical characterization of granulocytic pyrogen.J Exp Med1968https://conductscience.org/library/papers/5635382PubMed
1814,316,942STUDIES ON TUBERCULIN FEVER. 3. MECHANISMS INVOLVED IN THE RELEASE OF ENDOGENOUS PYROGEN IN VITRO.J Exp Med1965https://conductscience.org/library/papers/14316942PubMed
1914,453,159Studies on the pathogensis of fever. IX. The production of endogenous pyrogen by polymorphonuclear leucocytes.J Exp Med1962https://conductscience.org/library/papers/14453159PubMed
206,028,491Release of an endogenous pyrogen in vitro from rabbit mononuclear cells.J Exp Med1967https://conductscience.org/library/papers/6028491PubMed
225,793,046Phagocytosis by human blood leucocytes during suppression of glycolysis.Exp Cell Res1969https://conductscience.org/library/papers/5793046PubMed
2314,157,026STUDIES ON THE PATHOGENESIS OF FEVER. 13. THE EFFECT OF PHAGOCYTOSIS ON THE RELEASE OF ENDOGENOUS PYROGEN BY POLYMORPHONUCLEAR LEUKOCYTES.J Exp Med1964https://conductscience.org/library/papers/14157026PubMed

See all 22 references

Cited by18

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 42 citations.

PMIDTitleJournalYearIn PapersSource
16,148,175Circulating inflammatory mediators during start of fever in differential diagnosis of gram-negative and gram-positive infections in leukopenic rats.Clin Diagn Lab Immunol2005https://conductscience.org/library/papers/16148175PubMed
6,758,374Fever: its history, cause, and function.Yale J Biol Med1982https://conductscience.org/library/papers/6758374PubMed
6,750,226Production of fever and its effects on the host.Klin Wochenschr1982https://conductscience.org/library/papers/6750226PubMed
6,416,039Molecular mechanisms in endotoxin fever.Agents Actions1983https://conductscience.org/library/papers/6416039PubMed
4,829,934Demonstration and characterization of two distinct human leukocytic pyrogens.J Exp Med1974https://conductscience.org/library/papers/4829934PubMed
4,611,062Pyrogen release in vitro by lymphoid tissues from patients with Hodgkin's disease.Yale J Biol Med1974https://conductscience.org/library/papers/4611062PubMed
4,573,840Synthesis of endogenous pyrogen by rabbit leukocytes.J Exp Med1973https://conductscience.org/library/papers/4573840PubMed
4,427,091Studies on the mechanism of endogenous pyrogen production. III. Human blood monocytes.J Exp Med1974https://conductscience.org/library/papers/4427091PubMed
4,426,696Studies on the mechanism of endogenous pyrogen production. II. Role of cell products in the regulation of pyrogen release from blood leukocytes.Infect Immun1974https://conductscience.org/library/papers/4426696PubMed
4,262,347Pathologic mechanisms in neutrophil-mediated injury.Am J Pathol1972https://conductscience.org/library/papers/4262347PubMed
3,862,287Effect of protein synthesis inhibitors on leukocytic pyrogen-induced in vitro hypothalamic prostaglandin production.Yale J Biol Med1985https://conductscience.org/library/papers/3862287PubMed
2,994,306Studies on the production of endogenous pyrogen by rabbit monocytes: the role of calcium and cyclic nucleotides.Yale J Biol Med1985https://conductscience.org/library/papers/2994306PubMed
1,262,782Colchicine stimulation of pyrogen production by human blood leukocytes.J Exp Med1976https://conductscience.org/library/papers/1262782PubMed
874,874Endogenous pyrogen-like substance produced by reptiles.J Physiol1977https://conductscience.org/library/papers/874874PubMed
680,947A new sensitive method for detecting human endogenous (leukocyte) pyrogen.Inflammation1978https://conductscience.org/library/papers/680947PubMed
552,177The Jeremiah Metzger Lecture. The pathogenesis of fever in human subjects.Trans Am Clin Climatol Assoc1980https://conductscience.org/library/papers/552177PubMed
390,356Temperature and host defense.Microbiol Rev1979https://conductscience.org/library/papers/390356PubMed
233,905Differences in pyrogen production by mononuclear phagocytes and by fibroblasts or HeLa cells.J Exp Med1977https://conductscience.org/library/papers/233905PubMed

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

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Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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