Paper412251
Expression in Escherichia coli of a chemically synthesized gene for the hormone somatostatin.
Itakura K and 6 others. Science, 1977. Cited by 583 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
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ConductScience Library. Expression in Escherichia coli of a chemically synthesized gene for the hormone somatostatin. Papers, record 412251. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/412251
Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
- Expression in Escherichia coli of a chemically synthesized gene for the hormone somatostatin.
- PubMed
Topics9
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| DNA, Recombinant | Major topic |
| Escherichia coli | Major topic |
| Genes | Major topic |
| Somatostatin | Major topic |
| Base Sequence | |
| Lactose Factors | |
| Plasmids | |
| Protein Precursors | |
| beta-Galactosidase |
Source PubMed
Cited by214
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 583 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 42,661,071 | Micro-engineering the future. | Nat Microbiol | 2026 | https://conductscience.org/library/papers/42661071 | PubMed |
| 42,465,305 | An engineered biofactory for efficient production of diverse recombinant superoxide dismutase isozymes loaded with specific metal ions for biochemical characterization. | bioRxiv | 2026 | https://conductscience.org/library/papers/42465305 | PubMed |
| 41,971,978 | ReCHEMbinant stapling enhances intracellular delivery and bioactivity of engineered protein inhibitors. | Chem | 2026 | https://conductscience.org/library/papers/41971978 | PubMed |
| 41,419,896 | A standardized set of pNX vectors for enhanced soluble expression of recombinant proteins in E. coli using small fusion tags. | Microb Cell Fact | 2025 | https://conductscience.org/library/papers/41419896 | PubMed |
| 41,395,802 | On the Choice of the Right Plasmid Vector(s) in the Times of Synthetic Biology. | Microb Biotechnol | 2025 | https://conductscience.org/library/papers/41395802 | PubMed |
| 41,257,068 | Toward the commercialization of recombinant pharmaceuticals expressed in plants. | Plant Biotechnol (Tokyo) | 2025 | https://conductscience.org/library/papers/41257068 | PubMed |
| 41,182,907 | A comprehensive review of genomic-scale genetic engineering as a strategy to improve bacterial productivity. | Microbiology (Reading) | 2025 | https://conductscience.org/library/papers/41182907 | PubMed |
| 40,762,489 | A large-scale screening campaign of putative carbohydrate-active enzymes reveals a novel xylanase from anaerobic gut fungi. | mBio | 2025 | https://conductscience.org/library/papers/40762489 | PubMed |
| 40,698,392 | Advances in Peptidomimetics for Next-Generation Therapeutics: Strategies, Modifications, and Applications. | Chem Rev | 2025 | https://conductscience.org/library/papers/40698392 | PubMed |
| 40,573,887 | The Bioengineering of Insect Cell Lines for Biotherapeutics and Vaccine Production: An Updated Review. | Vaccines (Basel) | 2025 | https://conductscience.org/library/papers/40573887 | PubMed |
| 39,966,245 | Asilomar, Gene Cloning's Origins, and Its Commercial Fate. | J Hist Biol | 2025 | https://conductscience.org/library/papers/39966245 | PubMed |
| 39,962,275 | Money and murder: the dark side of the Asilomar meeting on recombinant DNA. | Nature | 2025 | https://conductscience.org/library/papers/39962275 | PubMed |
| 39,584,990 | A Brief Chronicle of Antibody Research and Technological Advances. | Antibodies (Basel) | 2024 | https://conductscience.org/library/papers/39584990 | PubMed |
| 38,840,157 | A production platform for disulfide-bonded peptides in the periplasm of Escherichia coli. | Microb Cell Fact | 2024 | https://conductscience.org/library/papers/38840157 | PubMed |
| 38,805,426 | Identifying widespread and recurrent variants of genetic parts to improve annotation of engineered DNA sequences. | PLoS One | 2024 | https://conductscience.org/library/papers/38805426 | PubMed |
| 38,750,104 | POSoligo software for in vitro gene synthesis. | Sci Rep | 2024 | https://conductscience.org/library/papers/38750104 | PubMed |
| 38,148,861 | The advent of plant cells in bioreactors. | Front Plant Sci | 2023 | https://conductscience.org/library/papers/38148861 | PubMed |
| 38,033,727 | Bringing enzymes to the proximity party. | RSC Chem Biol | 2023 | https://conductscience.org/library/papers/38033727 | PubMed |
| 37,764,879 | More than Three Decades of Bm86: What We Know and Where to Go. | Pathogens | 2023 | https://conductscience.org/library/papers/37764879 | PubMed |
| 36,968,340 | Prediction of strain engineerings that amplify recombinant protein secretion through the machine learning approach MaLPHAS. | Eng Biol | 2022 | https://conductscience.org/library/papers/36968340 | PubMed |
Genes2
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes | Source |
|---|---|---|---|---|
| GLB1 | 2,720 | PubTator's text mining | https://conductscience.org/library/genes/2720 | NCBI Gene |
| SST | 6,750 | PubTator's text mining | https://conductscience.org/library/genes/6750 | NCBI Gene |
Data1
The data bank entries PubMed's record names. Trial numbers are under Trials.
| Data bank | Accession |
|---|---|
| GENBANK | M10835 |
Source GENBANK
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
None in this release
- Grants
- Trials
- Comments and corrections
- References
- Drugs
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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