Paper · 41355768

Unraveling the Potential of Small Molecule Heparin Glycomimetics in Neuroregenerative Therapeutics.

Özkan M and 8 others. J Am Chem Soc, 2025. Cited by 1 paper, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Unraveling the Potential of Small Molecule Heparin Glycomimetics in Neuroregenerative Therapeutics. Papers, record 41355768. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/41355768

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Unraveling the Potential of Small Molecule Heparin Glycomimetics in Neuroregenerative Therapeutics.; PubMed
Journal: J Am Chem Soc; PubMed
Year: 2025; PubMed
Publication types: Journal Article, Research Support, Non-U.S. Gov't; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/41355768/; PubMed
DOI: https://doi.org/10.1021/jacs.5c13142; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC12715788/; PubMed
The journal: https://conductscience.org/library/journal-index/7503056; PubMed
Citations, by iCite: 1; iCite
Revised in PubMed: 2026-09-25; PubMed

Authors9

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	ORCID iD
1	Özkan M	Melis
2	Cellot G	Giada	https://orcid.org/0000-0001-9198-8402
3	Pawar S	Sujeet	https://orcid.org/0000-0003-0924-6464
4	Sardana D	Deepika	https://orcid.org/0000-0002-1798-3934
5	Barravecchia I	Ivana
6	Ballerini L	Laura	https://orcid.org/0000-0001-8420-0787
7	Angeloni D	Debora
8	Micera S	Silvestro
9	Stellacci F	Francesco	https://orcid.org/0000-0003-4635-6080

Source PubMed

Topics10

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Heparin	Major topic
Nerve Regeneration	Major topic
Small Molecule Libraries	Major topic
Biomimetic Materials	Major topic
Animals
Rats
Humans
PC12 Cells
Neurons
Heparan Sulfate

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References82

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	29,229,841	Predicting glycosaminoglycan surface protein interactions and implications for studying axonal growth.	Proc Natl Acad Sci U S A	2017	https://conductscience.org/library/papers/29229841	PubMed
2	23,529,843	Calcium signals and FGF-2 induced neurite growth in cultured parasympathetic neurons: spatial localization and mechanisms of activation.	Pflugers Arch	2013	https://conductscience.org/library/papers/23529843	PubMed
3	23,019,343	Diversification of the structural determinants of fibroblast growth factor-heparin interactions: implications for binding specificity.	J Biol Chem	2012	https://conductscience.org/library/papers/23019343	PubMed
4	23,275,175	FGF-2 low molecular weight selectively promotes neuritogenesis of motor neurons in vitro.	Mol Neurobiol	2013	https://conductscience.org/library/papers/23275175	PubMed
5	32,099,190	Multi-target approaches to CNS repair: olfactory mucosa-derived cells and heparan sulfates.	Nat Rev Neurol	2020	https://conductscience.org/library/papers/32099190	PubMed
6	22,411,830	A sulfated carbohydrate epitope inhibits axon regeneration after injury.	Proc Natl Acad Sci U S A	2012	https://conductscience.org/library/papers/22411830	PubMed
7	28,878,012	Synthetic oligosaccharides can replace animal-sourced low-molecular weight heparins.	Sci Transl Med	2017	https://conductscience.org/library/papers/28878012	PubMed
8	9,882,700	In vivo involvement of heparan sulfate proteoglycan in the bioavailability, internalization, and catabolism of exogenous basic fibroblast growth factor.	Mol Pharmacol	1999	https://conductscience.org/library/papers/9882700	PubMed
9	14,735,113	Homeostatic plasticity in the developing nervous system.	Nat Rev Neurosci	2004	https://conductscience.org/library/papers/14735113	PubMed
10	31,526,478	Self-organization of modular network architecture by activity-dependent neuronal migration and outgrowth.	Elife	2019	https://conductscience.org/library/papers/31526478	PubMed

1 to 10 of 82

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Cited by0

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 1 citation.

None in this release.

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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