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Paper · 41365890

Efficient high-precision transgene knock-in by Recombinases (Redα/β)-enhanced DNA integration-CRISPR-Cas9 (RED-CRISPR).

Li W and 17 others. Nat Commun, 2025. Cited by 6 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Efficient high-precision transgene knock-in by Recombinases (Redα/β)-enhanced DNA integration-CRISPR-Cas9 (RED-CRISPR). Papers, record 41365890. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/41365890

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Efficient high-precision transgene knock-in by Recombinases (Redα/β)-enhanced DNA integration-CRISPR-Cas9 (RED-CRISPR).
PubMed
Journal
Nat Commun
PubMed
Year
2025
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
6
iCite
Relative citation ratio, by iCite
1.54, provisional
iCite
Revised in PubMed
2026-01-17
PubMed

Authors18

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Li WWenqinghttps://orcid.org/0009-0000-6591-9059
2Liu SSenquanhttps://orcid.org/0000-0003-1444-5994
3Fang XXiaoyu
4Zou JJiaqi
5Jiang QQin
6Min XXiaolin
7Zhu XXiaolihttps://orcid.org/0009-0007-7819-7762
8Cao YYuzhu
9Gao XXiaoxiao
10Han WWenjiehttps://orcid.org/0000-0002-2779-9196

1 to 10 of 18Source PubMed

See all 18 authors

Topics11

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
CRISPR-Cas SystemsMajor topic
Gene Knock-In TechniquesMajor topic
TransgenesMajor topic
Gene EditingMajor topic
RecombinasesMajor topic
Animals
Mice
Humans
Recombinational DNA Repair
DNA
HEK293 Cells

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References101

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
118,230,724Identification and analysis of recombineering functions from Gram-negative and Gram-positive bacteria and their phages.Proc Natl Acad Sci U S A2008https://conductscience.org/library/papers/18230724PubMed
235,534,455Targeting double-strand break indel byproducts with secondary guide RNAs improves Cas9 HDR-mediated genome editing efficiencies.Nat Commun2022https://conductscience.org/library/papers/35534455PubMed
310,585,965Recombinational repair of DNA damage in Escherichia coli and bacteriophage lambda.Microbiol Mol Biol Rev1999https://conductscience.org/library/papers/10585965PubMed
436,153,319Comprehensive assessment of miniature CRISPR-Cas12f nucleases for gene disruption.Nat Commun2022https://conductscience.org/library/papers/36153319PubMed
510,921,910RecE/RecT and Redalpha/Redbeta initiate double-stranded break repair by specifically interacting with their respective partners.Genes Dev2000https://conductscience.org/library/papers/10921910PubMed
631,147,612The next generation of CRISPR-Cas technologies and applications.Nat Rev Mol Cell Biol2019https://conductscience.org/library/papers/31147612PubMed
726,923,600Improved Genome Editing Efficiency and Flexibility Using Modified Oligonucleotides with TALEN and CRISPR-Cas9 Nucleases.Cell Rep2016https://conductscience.org/library/papers/26923600PubMed
836,639,728Assessing and advancing the safety of CRISPR-Cas tools: from DNA to RNA editing.Nat Commun2023https://conductscience.org/library/papers/36639728PubMed
95,553,408The role of exonuclease and beta protein of phage lambda in genetic recombination. 3. Binding to deoxyribonucleic acid.J Biol Chem1971https://conductscience.org/library/papers/5553408PubMed
1021,243,013Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures.Cell Res2011https://conductscience.org/library/papers/21243013PubMed

1 to 10 of 101

See all 101 references

Cited by6

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 6 citations.

PMIDTitleJournalYearIn PapersSource
42,891,351Strategies and mechanisms of precision genome engineering: From gene editing to genome writing.IMetaOmics2026https://conductscience.org/library/papers/42891351PubMed
42,755,359Large serine recombinase-mediated gene insertion for high-throughput screens: advantages, design principles, and applications.Nucleic Acids Res2026https://conductscience.org/library/papers/42755359PubMed
42,464,282Establishment of SRLC: a multiplex genome editing technology for Saccharomyces cerevisiae and its application in metabolic engineering of malonyl-CoA pathway.Microb Cell Fact2026https://conductscience.org/library/papers/42464282PubMed
42,373,632Development of efficient genetic toolkits and heterologous chassis for bioprospecting of myxobacteria.Nat Commun2026https://conductscience.org/library/papers/42373632PubMed
41,993,426Ultra-large targeted DNA integrations in primary human cells.bioRxiv2026https://conductscience.org/library/papers/41993426PubMed
41,914,500Enhancement of single-stranded template annealing activity by Rad52 during repair of CRISPR-induced dsDNA breaks.Nucleic Acids Res2026https://conductscience.org/library/papers/41914500PubMed

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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