Paper · 416165

Cytotoxic T-cell responses to H-Y: mapping of the Ir genes.

Hurme M and 3 others. J Exp Med, 1978. Cited by 95 papers, by iCite.

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ConductScience Library. Cytotoxic T-cell responses to H-Y: mapping of the Ir genes. Papers, record 416165. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/416165

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Cytotoxic T-cell responses to H-Y: mapping of the Ir genes.; PubMed
Journal: J Exp Med; PubMed
Year: 1978; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/416165/; PubMed
DOI: https://doi.org/10.1084/jem.147.3.758; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC2184193/; PubMed
The journal: https://conductscience.org/library/journal-index/2985109R; PubMed
Citations, by iCite: 95; iCite
Relative citation ratio, by iCite: 1.96; iCite
Revised in PubMed: 2019-05-08; PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Hurme M	M
2	Hetherington CM	C M
3	Chandler PR	P R
4	Simpson E	E

Source PubMed

Topics12

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Cytotoxicity, Immunologic	Major topic
Genes, MHC Class II	Major topic
Histocompatibility Antigens	Major topic
T-Lymphocytes	Major topic
Animals
Chromosome Mapping
Female
Genes, Dominant
H-2 Antigens
Male
Mice
Y Chromosome

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References18

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	70,400	Responsiveness to HY antigen Ir gene complementation and target cell specificity.	Immunol Rev	1977	https://conductscience.org/library/papers/70400	PubMed
2	66,186	The original function of MHC antigens as the general plasma membrane anchorage site of organogenesis-directing proteins.	Immunol Rev	1977	https://conductscience.org/library/papers/66186	PubMed
3	61,822	Cooperation between mouse T-cell subpopulations in the cell-mediated response to a natural poxvirus pathogen.	Cell Immunol	1976	https://conductscience.org/library/papers/61822	PubMed
4	63,988	Two different VH gene products make up the T-cell receptors.	Scand J Immunol	1976	https://conductscience.org/library/papers/63988	PubMed
5	193,995	In vitro primary induction of cytotoxic T cells against virus-infected syngeneic cells.	J Immunol Methods	1977	https://conductscience.org/library/papers/193995	PubMed
6	135,687	Micromethods for induction and assay of mouse mixed lymphocyte reactions and cytotoxicity.	Eur J Immunol	1976	https://conductscience.org/library/papers/135687	PubMed
7	416,166	Cytotoxic T-cell responses to H-Y: correlation with the rejection of syngeneic male skin grafts.	J Exp Med	1978	https://conductscience.org/library/papers/416166	PubMed
8	302,210	H-2 gene complementation in cytotoxic T cell responses of female against male cells.	Eur J Immunol	1977	https://conductscience.org/library/papers/302210	PubMed
9	301,314	Immune-response gene control of cytotoxic T-cell responses to H-Y.	Transplant Proc	1977	https://conductscience.org/library/papers/301314	PubMed
10	301,177	Histocompatibility linked immune responsiveness and restrictions imposed on sensitized lymphocytes.	J Exp Med	1977	https://conductscience.org/library/papers/301177	PubMed

1 to 10 of 18

See all 18 references

Cited by29

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 95 citations.

PMID	Title	Journal	Year	In Papers	Source
22,457,925	A new cytotoxic lymphocyte-defined antigen coded by a gene closely linked to the H-3 locus.	Immunogenetics	1980	https://conductscience.org/library/papers/22457925	PubMed
20,213,737	Mice lacking C1q or C3 show accelerated rejection of minor H disparate skin grafts and resistance to induction of tolerance.	Eur J Immunol	2010	https://conductscience.org/library/papers/20213737	PubMed
18,154,613	Special regulatory T-cell review: Regulation of immune responses--examining the role of T cells.	Immunology	2008	https://conductscience.org/library/papers/18154613	PubMed
7,049,909	Evidence for two male antigens in mice.	Immunogenetics	1982	https://conductscience.org/library/papers/7049909	PubMed
7,026,417	The H-Y antigen and its role in natural transplantation.	Hum Genet	1981	https://conductscience.org/library/papers/7026417	PubMed
7,009,416	Immunogenetic control of the response of female mice to male tissue grafts.	Immunogenetics	1981	https://conductscience.org/library/papers/7009416	PubMed
6,977,489	MHC restriction of male-antigen-specific T helper cells collaborating in antibody responses.	Immunogenetics	1982	https://conductscience.org/library/papers/6977489	PubMed
6,975,939	Influence of H-2 antigen expression on killer T cell specificity, differentiation, and induction.	Proc Natl Acad Sci U S A	1981	https://conductscience.org/library/papers/6975939	PubMed
6,974,690	The characterization of the delayed-type hypersensitivity reaction to H-Y antigens.	Immunogenetics	1980	https://conductscience.org/library/papers/6974690	PubMed
6,802,751	Non-H-2 and H-2-linked immune response genes control the cytotoxic T-cell response to H-Y.	Immunogenetics	1982	https://conductscience.org/library/papers/6802751	PubMed

1 to 10 of 29

See all 29 cited by

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

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ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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