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Paper · 42007332

Efficacy and safety of efruxifermin for patients with NASH/MASH: an updated systematic review and meta-analysis.

Xiao YJ and 7 others. Front Pharmacol, 2025. Cited by 8 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Efficacy and safety of efruxifermin for patients with NASH/MASH: an updated systematic review and meta-analysis. Papers, record 42007332. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/42007332

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Efficacy and safety of efruxifermin for patients with NASH/MASH: an updated systematic review and meta-analysis.
PubMed
Journal
Front Pharmacol
PubMed
Year
2025
PubMed
Publication types
Journal Article, Systematic Review
PubMed
Citations, by iCite
8
iCite
Relative citation ratio, by iCite
5.97, provisional
iCite
Revised in PubMed
2026-08-13
PubMed

Authors8

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Xiao YJYa-Jun
2Liu XPXue-Ping
3Zhang YLYan-Ling
4Cheng YYan
5Tian XLXiao-Li
6Liu YQYan-Qun
7Deng CLCun-Liang
8Sun HHao

Source PubMed

Topics0

NLM's MeSH indexing of the paper, its major topics first.

None in this release.

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References39

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
138,097,670A pivotal year for NAFLD and NASH therapeutics.Nat Rev Endocrinol2024https://conductscience.org/library/papers/38097670PubMed
240,520,164A systematic review and meta-analysis of efruxifermin's efficacy in improving liver fibrosis in patients with NASH/MASH.Front Pharmacol2025https://conductscience.org/library/papers/40520164PubMed
329,940,269Endoplasmic reticulum stress signalling and the pathogenesis of non-alcoholic fatty liver disease.J Hepatol2018https://conductscience.org/library/papers/29940269PubMed
433,782,057The PRISMA 2020 statement: an updated guideline for reporting systematic reviews.BMJ2021https://conductscience.org/library/papers/33782057PubMed
537,363,821A multisociety Delphi consensus statement on new fatty liver disease nomenclature.Hepatology2023https://conductscience.org/library/papers/37363821PubMed
636,976,456Metabolic dysfunction-associated fatty liver disease (MAFLD): an update of the recent advances in pharmacological treatment.J Physiol Biochem2023https://conductscience.org/library/papers/36976456PubMed
734,536,190FGF21 ameliorates hepatic fibrosis by multiple mechanisms.Mol Biol Rep2021https://conductscience.org/library/papers/34536190PubMed
840,341,827Efruxifermin in Compensated Liver Cirrhosis Caused by MASH.N Engl J Med2025https://conductscience.org/library/papers/40341827PubMed
933,381,084FGF21: An Emerging Therapeutic Target for Non-Alcoholic Steatohepatitis and Related Metabolic Diseases.Front Endocrinol (Lausanne)2020https://conductscience.org/library/papers/33381084PubMed
1036,727,674AASLD Practice Guidance on the clinical assessment and management of nonalcoholic fatty liver disease.Hepatology2023https://conductscience.org/library/papers/36727674PubMed

Cited by3

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 8 citations.

PMIDTitleJournalYearIn PapersSource
42,640,441Holding the Line: Navigating Upadacitinib-Induced Neutropenia in Refractory Ulcerative Colitis.Dig Dis Sci2026https://conductscience.org/library/papers/42640441PubMed
42,213,392Polymer-Based and Biomaterial Encapsulation of Probiotics for Improved Viability.Probiotics Antimicrob Proteins2026https://conductscience.org/library/papers/42213392PubMed
41,874,589Exposure to second-generation flame retardants and risk of metabolic diseases: a systematic review and meta-analysis.Arch Toxicol2026https://conductscience.org/library/papers/41874589PubMed

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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