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Paper · 4215083

Organization of immunoglobulin genes: reiteration frequency of the mouse kappa chain constant region gene.

Honjo T and 4 others. Proc Natl Acad Sci U S A, 1974. Cited by 86 papers, by iCite.

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ConductScience Library. Organization of immunoglobulin genes: reiteration frequency of the mouse kappa chain constant region gene. Papers, record 4215083. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/4215083

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Organization of immunoglobulin genes: reiteration frequency of the mouse kappa chain constant region gene.
PubMed
Journal
Proc Natl Acad Sci U S A
PubMed
Year
1974
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
86
iCite
Relative citation ratio, by iCite
2.01
iCite
Revised in PubMed
2019-05-01
PubMed

Authors5

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Honjo TT
2Packman SS
3Swan DD
4Nau MM
5Leder PP

Source PubMed

Topics19

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
DNA, NeoplasmMajor topic
GenesMajor topic
Immunoglobulin FragmentsMajor topic
Immunoglobulin kappa-ChainsMajor topic
Animals
Base Sequence
Cell Line
Centrifugation, Density Gradient
Electrophoresis, Polyacrylamide Gel
Genetic Code
Haploidy
Kinetics
Mice
Neoplasms, Experimental
Nucleic Acid Hybridization
Plasmacytoma
RNA, Messenger
Transcription, Genetic
Tritium

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References53

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
14,181,523A "Lepore" type of hybrid gamma-globulin.Proc Natl Acad Sci U S A1969https://conductscience.org/library/papers/4181523PubMed
24,162,931Mechanism of antibody synthesis: size differences between mouse kappa chains.Science1967https://conductscience.org/library/papers/4162931PubMed
34,160,200The molecular basis of antibody formation: a paradox.Proc Natl Acad Sci U S A1965https://conductscience.org/library/papers/4160200PubMed
44,551,278Molecular weight determination of nucleic acids by gel electrophoresis in non-aqueous solution.Nat New Biol1972https://conductscience.org/library/papers/4551278PubMed
54,165,728Antibody variability. Somatic recombination between the elements of "antibody gene pairs" may explain antibody variability.Science1967https://conductscience.org/library/papers/4165728PubMed
64,131,387Characterization of synthetic rabbit globin DNA.Arch Biochem Biophys1973https://conductscience.org/library/papers/4131387PubMed
75,435,789Distribution of allotypic specificities A1, A2, A14, and A15 among immunoglobulin G molecules.J Immunol1970https://conductscience.org/library/papers/5435789PubMed
84,638,756A comparison of globin genes in duck reticulocytes and liver cells.Biochem Biophys Res Commun1972https://conductscience.org/library/papers/4638756PubMed
95,965,537Origin of antibody variation.Nature1966https://conductscience.org/library/papers/5965537PubMed
105,279,812Genetic control of variable and constant regions of immunoglobulin heavy chains.Nat New Biol1971https://conductscience.org/library/papers/5279812PubMed

Cited by20

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 86 citations.

PMIDTitleJournalYearIn PapersSource
6,767,246Rearrangement of immunoglobulin gamma 1-chain gene and mechanism for heavy-chain class switch.Proc Natl Acad Sci U S A1980https://conductscience.org/library/papers/6767246PubMed
6,262,799Nucleotide sequence of the thymidine kinase gene of herpes simplex virus type 1.Proc Natl Acad Sci U S A1981https://conductscience.org/library/papers/6262799PubMed
6,244,580Organization of kappa light chain genes in germ-line and somatic tissue.Proc Natl Acad Sci U S A1980https://conductscience.org/library/papers/6244580PubMed
6,186,903Genetic analysis of alpha-fetoprotein synthesis in mice.Mol Cell Biol1982https://conductscience.org/library/papers/6186903PubMed
6,182,563Transcriptional control of the murine albumin/alpha-fetoprotein locus during development.Proc Natl Acad Sci U S A1982https://conductscience.org/library/papers/6182563PubMed
1,090,629Messenger RNA metabolism of animal cells. Possible involvement of untranslated sequences and mRNA-associated proteins.J Cell Biol1975https://conductscience.org/library/papers/1090629PubMed
824,647Evidence for somatic rearrangement of immunoglobulin genes coding for variable and constant regions.Proc Natl Acad Sci U S A1976https://conductscience.org/library/papers/824647PubMed
819,932Size differences among immunoglobulin heavy chains from phosphorylcholine-binding proteins.Proc Natl Acad Sci U S A1976https://conductscience.org/library/papers/819932PubMed
815,908Transcription in vitro of immunoglobulin kappa light chain genes in isolated mouse myeloma nuclei and chromatin.Proc Natl Acad Sci U S A1976https://conductscience.org/library/papers/815908PubMed
815,907No detectable reiteration of genes coding for mouse MOPC 41 immunoglobulin light-chain mRNA.Proc Natl Acad Sci U S A1976https://conductscience.org/library/papers/815907PubMed

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Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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