Paper · 42601409

New paradigm of q-CAR drug development targeting disease-specific protein conformations.

Ye L. NPJ Drug Discov, 2026. Cited by 0 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. New paradigm of q-CAR drug development targeting disease-specific protein conformations. Papers, record 42601409. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/42601409

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: New paradigm of q-CAR drug development targeting disease-specific protein conformations.; PubMed
Journal: NPJ Drug Discov; PubMed
Year: 2026; PubMed
Publication types: Journal Article, Review; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/42601409/; PubMed
DOI: https://doi.org/10.1038/s44386-026-00057-2; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC13476234/; PubMed
The journal: https://conductscience.org/library/journal-index/9918993695206676; PubMed
Citations, by iCite: 0; iCite
Revised in PubMed: 2026-08-18; PubMed

Authors1

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Ye L	Libin

Source PubMed

Topics0

NLM's MeSH indexing of the paper, its major topics first.

None in this release.

Grants4

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes it	Agency	Country	NIH project	Stated by	Source
R01 GM149659	NIGMS NIH HHS	United States	R01GM149659	PubMed	NIH RePORTER
R21 ES035378	NIEHS NIH HHS	United States	R21ES035378	PubMed	NIH RePORTER
1R01GM149659	NIGMS NIH HHS	United States	R01GM149659	PubMed	NIH RePORTER
DE-AR0002095	Department of Energy			PubMed	PubMed

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References161

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	20,694,682	An historical overview of drug discovery.	Methods Mol Biol	2009	https://conductscience.org/library/papers/20694682	PubMed
2	9,788,996	Directed evolution of a thermostable esterase.	Proc Natl Acad Sci U S A	1998	https://conductscience.org/library/papers/9788996	PubMed
3	31,164,742	Drug pipeline 1Q19.	Nat Biotechnol	2019	https://conductscience.org/library/papers/31164742	PubMed
4	16,683,750	Characterization of the dynamics of biomacromolecules using rotating-frame spin relaxation NMR spectroscopy.	Chem Rev	2006	https://conductscience.org/library/papers/16683750	PubMed
5	12,669,031	A brief history of novel drug discovery technologies.	Nat Rev Drug Discov	2003	https://conductscience.org/library/papers/12669031	PubMed
6	37,591,206	Learning protein fitness landscapes with deep mutational scanning data from multiple sources.	Cell Syst	2023	https://conductscience.org/library/papers/37591206	PubMed
7	26,428,732	Cell-Based Assay Design for High-Content Screening of Drug Candidates.	J Microbiol Biotechnol	2016	https://conductscience.org/library/papers/26428732	PubMed
8	38,354,979	Personalized Drug Therapy: Innovative Concept Guided With Proteoformics.	Mol Cell Proteomics	2024	https://conductscience.org/library/papers/38354979	PubMed
9	14,522,049	The process of structure-based drug design.	Chem Biol	2003	https://conductscience.org/library/papers/14522049	PubMed
10	33,337,877	Ligand-Binding-Site Refinement to Generate Reliable Holo Protein Structure Conformations from Apo Structures.	J Chem Inf Model	2021	https://conductscience.org/library/papers/33337877	PubMed

1 to 10 of 161

See all 161 references

Cited by1

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 0 citations.

PMID	Title	Journal	Year	In Papers
42,818,087	An Excelled Trifluorinated Probe for GPCR Conformational Quantification.	bioRxiv	2026	https://conductscience.org/library/papers/42818087

Source PubMed

Genes1

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes
CXADRP1	653,108	PubTator's text mining	https://conductscience.org/library/genes/653108

Source NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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