Paper · 42754591
Structure-based design of subtype-selective psychedelic analogs.
Li H and 10 others. Nat Commun, 2026. Cited by 1 paper, by iCite.
11 sourcespapers-2026-11-12-0.1.0
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ConductScience Library. Structure-based design of subtype-selective psychedelic analogs. Papers, record 42754591. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/42754591
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Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
Topics12
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Hallucinogens | Major topic |
| Receptor, Serotonin, 5-HT2A | Major topic |
| Drug Design | Major topic |
| Serotonin 5-HT2 Receptor Agonists | Major topic |
| Receptor, Serotonin, 5-HT2B | Major topic |
| Cryoelectron Microscopy | |
| Humans | |
| Binding Sites | |
| Pharmacophore | |
| Animals | |
| Models, Molecular | |
| HEK293 Cells |
Source PubMed
Grants4
Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.
| Grant, as the record writes it | Agency | Country | NIH project | Stated by |
|---|---|---|---|---|
| 82525061 | National Natural Science Foundation of China (National Science Foundation of China) | PubMed | ||
| 22377077 | National Natural Science Foundation of China (National Science Foundation of China) | PubMed | ||
| 82225045 | National Natural Science Foundation of China (National Science Foundation of China) | PubMed | ||
| 82530106 | National Natural Science Foundation of China (National Science Foundation of China) | PubMed |
Source PubMed
Trials0
The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.
None in this release.
Comments and corrections0
PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.
None in this release.
References68
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 9,731,087 | A population-based study of appetite-suppressant drugs and the risk of cardiac-valve regurgitation. | N Engl J Med | 1998 | https://conductscience.org/library/papers/9731087 | PubMed |
| 2 | 34,887,590 | Structure-based design of a novel third-generation antipsychotic drug lead with potential antidepressant properties. | Nat Neurosci | 2022 | https://conductscience.org/library/papers/34887590 | PubMed |
| 3 | 38,091,366 | A new variant of the colistin resistance gene MCR-1 with co-resistance to β-lactam antibiotics reveals a potential novel antimicrobial peptide. | PLoS Biol | 2023 | https://conductscience.org/library/papers/38091366 | PubMed |
| 4 | 29,051,383 | D4 dopamine receptor high-resolution structures enable the discovery of selective agonists. | Science | 2017 | https://conductscience.org/library/papers/29051383 | PubMed |
| 5 | 16,182,563 | Automated electron microscope tomography using robust prediction of specimen movements. | J Struct Biol | 2005 | https://conductscience.org/library/papers/16182563 | PubMed |
| 6 | 38,593,423 | Synthesis and Structure-Activity Relationships of 2,5-Dimethoxy-4-Substituted Phenethylamines and the Discovery of CYB210010: A Potent, Orally Bioavailable and Long-Acting Serotonin 5-HT2 Receptor Agonist. | J Med Chem | 2024 | https://conductscience.org/library/papers/38593423 | PubMed |
| 7 | 36,536,256 | Human loss-of-function variants in the serotonin 2C receptor associated with obesity and maladaptive behavior. | Nat Med | 2022 | https://conductscience.org/library/papers/36536256 | PubMed |
| 8 | 34,797,943 | Molecular insights into psychedelic drug action. | J Neurochem | 2022 | https://conductscience.org/library/papers/34797943 | PubMed |
| 9 | 30,187,647 | Homology modeling in drug discovery: Overview, current applications, and future perspectives. | Chem Biol Drug Des | 2019 | https://conductscience.org/library/papers/30187647 | PubMed |
| 10 | 38,552,625 | Flexible scaffold-based cheminformatics approach for polypharmacological drug design. | Cell | 2024 | https://conductscience.org/library/papers/38552625 | PubMed |
1 to 10 of 68
See all 68 referencesCited by1
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 1 citation.
| PMID | Title | Journal | Year | In Papers |
|---|---|---|---|---|
| 42,766,262 | Identification of key molecules and pathways in CaOx crystal-induced renal injury based on metabolomics and proteomics. | Int Urol Nephrol | 2026 | https://conductscience.org/library/papers/42766262 |
Source PubMed
Genes1
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes |
|---|---|---|---|
| HTR2A | 3,356 | PubTator's text mining | https://conductscience.org/library/genes/3356 |
Source NCBI Gene
Drugs0
The drugs whose trials, in the Pipelines release, list the paper.
None in this release.
Data0
The data bank entries PubMed's record names. Trial numbers are under Trials.
None in this release.
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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