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Paper · 42836735

Pancreatic Cancer KRAS Breakthrough: Drug Graveyard No More.

Yu PY and 3 others. Clin Cancer Res, 2026.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Pancreatic Cancer KRAS Breakthrough: Drug Graveyard No More. Papers, record 42836735. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/42836735

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Pancreatic Cancer KRAS Breakthrough: Drug Graveyard No More.
Journal
Clin Cancer Res
Year
2026
Publication types
Journal Article
Revised in PubMed
2026-10-09

Source PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Yu PYPeter Yhttps://orcid.org/0000-0002-0384-9865
2Oberstein PEPaul Ehttps://orcid.org/0000-0001-5918-6004
3Maitra AAnirbanhttps://orcid.org/0000-0001-7923-9978
4Hidalgo MManuelhttps://orcid.org/0000-0002-3765-3318

Source PubMed

Topics0

NLM's MeSH indexing of the paper, its major topics first.

None in this release.

Grants4

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
K12 CA270377NCI NIH HHSUnited StatesK12CA270377PubMedNIH RePORTER
U01 CA200468NCI NIH HHSUnited StatesU01CA200468PubMedNIH RePORTER
U24 CA274274NCI NIH HHSUnited StatesU24CA274274PubMedNIH RePORTER
U54 CA274371NCI NIH HHSUnited StatesU54CA274371PubMedNIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References51

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
137,059,070Pancreatic cancer: Advances and challenges.Cell2023https://conductscience.org/library/papers/37059070PubMed
237,937,763Osimertinib with or without Chemotherapy in EGFR-Mutated Advanced NSCLC.N Engl J Med2023https://conductscience.org/library/papers/37937763PubMed
329,860,986Immunotherapy and Prevention of Pancreatic Cancer.Trends Cancer2018https://conductscience.org/library/papers/29860986PubMed
426,037,647Biochemical and Structural Analysis of Common Cancer-Associated KRAS Mutations.Mol Cancer Res2015https://conductscience.org/library/papers/26037647PubMed
537,099,736Adagrasib in Advanced Solid Tumors Harboring a KRASG12C Mutation.J Clin Oncol2023https://conductscience.org/library/papers/37099736PubMed
628,338,509Patterns, Timing, and Predictors of Recurrence Following Pancreatectomy for Pancreatic Ductal Adenocarcinoma.Ann Surg2018https://conductscience.org/library/papers/28338509PubMed
738,975,874Mechanisms of Resistance to Oncogenic KRAS Inhibition in Pancreatic Cancer.Cancer Discov2024https://conductscience.org/library/papers/38975874PubMed
836,546,651Sotorasib in KRAS p.G12C-Mutated Advanced Pancreatic Cancer.N Engl J Med2023https://conductscience.org/library/papers/36546651PubMed
929,229,669KRAS: The Critical Driver and Therapeutic Target for Pancreatic Cancer.Cold Spring Harb Perspect Med2018https://conductscience.org/library/papers/29229669PubMed
1024,256,730K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions.Nature2013https://conductscience.org/library/papers/24256730PubMed

1 to 10 of 51

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Cited by0

The papers in our copy of PubMed whose reference list names this one, newest first.

None in this release.

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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