Paper · 42850583

Decoding Biomolecular Phase Separation: From Physiological Roles to Pathological Mechanisms and Therapeutic Biomaterials Design.

Zhu J and 5 others. Adv Sci (Weinh), 2026.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Decoding Biomolecular Phase Separation: From Physiological Roles to Pathological Mechanisms and Therapeutic Biomaterials Design. Papers, record 42850583. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/42850583

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Decoding Biomolecular Phase Separation: From Physiological Roles to Pathological Mechanisms and Therapeutic Biomaterials Design.
Journal: Adv Sci (Weinh)
Year: 2026
Publication types: Journal Article, Review
PubMed: https://pubmed.ncbi.nlm.nih.gov/42850583/
DOI: https://doi.org/10.1002/advs.78087
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC13650032/
The journal: https://conductscience.org/library/journal-index/101664569
Revised in PubMed: 2026-10-11

Source PubMed

Authors6

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	ORCID iD
1	Zhu J	Jiawei
2	Dong J	Jingbo
3	Gong Q	Qiufang
4	Song X	Xuejiao	https://orcid.org/0000-0002-5833-7381
5	Shen Z	Zhifa
6	Liang C	Chao

Source PubMed

Topics0

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None in this release.

Grants2

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes it	Agency	Country	NIH project	Stated by
LQN25C100009	Zhejiang Province Natural Science Foundation			PubMed
82402497	National Natural Science Foundation of China			PubMed

Source PubMed

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

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None in this release.

References235

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	35,300,892	Regulation of gene expression by glycolytic and gluconeogenic enzymes.	Trends Cell Biol	2022	https://conductscience.org/library/papers/35300892	PubMed
2	34,753,899	rRNA biogenesis regulates mouse 2C-like state by 3D structure reorganization of peri-nucleolar heterochromatin.	Nat Commun	2021	https://conductscience.org/library/papers/34753899	PubMed
3	41,850,287	Deep-learning-based de novo discovery and design of therapeutics that reverse disease-associated transcriptional phenotypes.	Cell	2026	https://conductscience.org/library/papers/41850287	PubMed
4	22,398,450	Phase transitions in the assembly of multivalent signalling proteins.	Nature	2012	https://conductscience.org/library/papers/22398450	PubMed
5	42,180,533	Small molecules modulate the biomolecular condensates and liquid‒liquid phase separation.	Acta Pharm Sin B	2026	https://conductscience.org/library/papers/42180533	PubMed
6	26,317,470	A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation.	Cell	2015	https://conductscience.org/library/papers/26317470	PubMed
7	36,539,553	The dynamics of three-dimensional chromatin organization and phase separation in cell fate transitions and diseases.	Cell Regen	2022	https://conductscience.org/library/papers/36539553	PubMed
8	34,667,177	PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC.	Nat Commun	2021	https://conductscience.org/library/papers/34667177	PubMed
9	42,361,792	A negative regulator of mitochondrial complex I assembly adapts respiration to cellular energy demand.	Mol Cell	2026	https://conductscience.org/library/papers/42361792	PubMed
10	42,098,154	CCDC120 phase separation contributes to desmosomal integrity and cardiac function.	Nat Commun	2026	https://conductscience.org/library/papers/42098154	PubMed

1 to 10 of 235

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Cited by0

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None in this release.

Genes0

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None in this release.

Drugs0

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None in this release.

Data0

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None in this release.

Data dates

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PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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