Paper · 42875424
Antagonistic roles of histone H3 lysine methyltransferases dictate tumor immune surveillance.
Gladstein AC and 14 others. Nat Commun, 2026.
11 sourcespapers-2026-11-12-0.1.0
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ConductScience Library. Antagonistic roles of histone H3 lysine methyltransferases dictate tumor immune surveillance. Papers, record 42875424. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/42875424
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Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
- Antagonistic roles of histone H3 lysine methyltransferases dictate tumor immune surveillance.
- Journal
- Nat Commun
- Year
- 2026
- Publication types
- Journal Article, Research Support, N.I.H., Extramural
- Revised in PubMed
- 2026-10-22
Source PubMed
Topics15
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Histone-Lysine N-Methyltransferase | Major topic |
| Histones | Major topic |
| Lung Neoplasms | Major topic |
| Immunologic Surveillance | Major topic |
| Animals | |
| Mice | |
| Enhancer of Zeste Homolog 2 Protein | |
| Humans | |
| Methylation | |
| Proto-Oncogene Proteins p21(ras) | |
| Gene Expression Regulation, Neoplastic | |
| Cell Line, Tumor | |
| RNA, Double-Stranded | |
| Repressor Proteins | |
| Lysine |
Source PubMed
Grants6
Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.
| Grant, as the record writes it | Agency | Country | NIH project | Stated by | Source |
|---|---|---|---|---|---|
| R01-CA262619 | U.S. Department of Health & Human Services | NIH | National Cancer Institute (NCI) | R01CA262619 | PubMed | NIH RePORTER | |
| R01-CA279698, | U.S. Department of Health & Human Services | NIH | National Cancer Institute (NCI) | R01CA279698 | PubMed | NIH RePORTER | |
| R01-CA276350 | U.S. Department of Health & Human Services | NIH | National Cancer Institute (NCI) | R01CA276350 | PubMed | NIH RePORTER | |
| W81XWH2210742 | U.S. Department of Defense (United States Department of Defense) | PubMed | PubMed | ||
| W81XWH2210008 | U.S. Department of Defense (United States Department of Defense) | PubMed | PubMed | ||
| 2-T32-CA-15299-15 | U.S. Department of Health & Human Services | NIH | Division of Loan Repayment (DLR) | T32CA152991 | PubMed | NIH RePORTER |
Trials0
The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.
None in this release.
Comments and corrections0
PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.
None in this release.
References58
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 27,518,565 | Dual Chromatin and Cytoskeletal Remodeling by SETD2. | Cell | 2016 | https://conductscience.org/library/papers/27518565 | PubMed |
| 2 | 28,256,625 | Molecular basis for the role of oncogenic histone mutations in modulating H3K36 methylation. | Sci Rep | 2017 | https://conductscience.org/library/papers/28256625 | PubMed |
| 3 | 25,516,281 | Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. | Genome Biol | 2014 | https://conductscience.org/library/papers/25516281 | PubMed |
| 4 | 31,867,411 | Semi-quantitative Determination of Protein Expression using Immunohistochemistry Staining and Analysis: An Integrated Protocol. | Bio Protoc | 2019 | https://conductscience.org/library/papers/31867411 | PubMed |
| 5 | 31,147,750 | Understanding histone H3 lysine 36 methylation and its deregulation in disease. | Cell Mol Life Sci | 2019 | https://conductscience.org/library/papers/31147750 | PubMed |
| 6 | 22,588,877 | The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data. | Cancer Discov | 2012 | https://conductscience.org/library/papers/22588877 | PubMed |
| 7 | 35,581,654 | Structural and functional specificity of H3K36 methylation. | Epigenetics Chromatin | 2022 | https://conductscience.org/library/papers/35581654 | PubMed |
| 8 | 39,460,617 | The UCSC Genome Browser database: 2025 update. | Nucleic Acids Res | 2025 | https://conductscience.org/library/papers/39460617 | PubMed |
| 9 | 30,867,593 | Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally. | Nature | 2019 | https://conductscience.org/library/papers/30867593 | PubMed |
| 10 | 27,875,550 | An Alternative Approach to ChIP-Seq Normalization Enables Detection of Genome-Wide Changes in Histone H3 Lysine 27 Trimethylation upon EZH2 Inhibition. | PLoS One | 2016 | https://conductscience.org/library/papers/27875550 | PubMed |
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Genes0
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None in this release.
Drugs0
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Data0
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None in this release.
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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