Paper · 42889575

RTK-RAS pathway alterations in hepatocellular carcinoma and cholangiocarcinoma: a multicohort genomic and single-cell transcriptomic study.

Chen C and 4 others. Front Oncol, 2026.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. RTK-RAS pathway alterations in hepatocellular carcinoma and cholangiocarcinoma: a multicohort genomic and single-cell transcriptomic study. Papers, record 42889575. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/42889575

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Title: RTK-RAS pathway alterations in hepatocellular carcinoma and cholangiocarcinoma: a multicohort genomic and single-cell transcriptomic study.
Journal: Front Oncol
Year: 2026
Publication types: Journal Article
PubMed: https://pubmed.ncbi.nlm.nih.gov/42889575/
DOI: https://doi.org/10.3389/fonc.2026.1963032
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC13669719/
The journal: https://conductscience.org/library/journal-index/101568867
Revised in PubMed: 2026-10-19

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Authors5

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Chen C	Chongyuan
2	Xing R	Rongchun
3	Wen Y	Yuhong
4	Li M	Meiqi
5	Hu M	Mingzheng

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References59

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	40,198,372	FGFR2 fusion/rearrangement analysis in intrahepatic cholangiocarcinoma using DNA/RNA-based NGS and FISH.	Virchows Arch	2025	https://conductscience.org/library/papers/40198372	PubMed
2	29,307,467	Hepatocellular carcinoma.	Lancet	2018	https://conductscience.org/library/papers/29307467	PubMed
3	33,597,522	Inference and analysis of cell-cell communication using CellChat.	Nat Commun	2021	https://conductscience.org/library/papers/33597522	PubMed
4	20,196,867	A scaling normalization method for differential expression analysis of RNA-seq data.	Genome Biol	2010	https://conductscience.org/library/papers/20196867	PubMed
5	29,360,550	Genomic characterization of biliary tract cancers identifies driver genes and predisposing mutations.	J Hepatol	2018	https://conductscience.org/library/papers/29360550	PubMed
6	29,295,995	Perturbation-response genes reveal signaling footprints in cancer gene expression.	Nat Commun	2018	https://conductscience.org/library/papers/29295995	PubMed
7	25,822,088	Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets.	Nat Genet	2015	https://conductscience.org/library/papers/25822088	PubMed
8	27,622,582	Biliary cancer: Utility of next-generation sequencing for clinical management.	Cancer	2016	https://conductscience.org/library/papers/27622582	PubMed
9	36,476,645	Multiregional single-cell dissection of tumor and immune cells reveals stable lock-and-key features in liver cancer.	Nat Commun	2022	https://conductscience.org/library/papers/36476645	PubMed
10	26,258,846	Genomic spectra of biliary tract cancer.	Nat Genet	2015	https://conductscience.org/library/papers/26258846	PubMed

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PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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ClinicalTrials.govNo license stated
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iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

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ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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