Paper · 42930554

Epigenetic Viral Mimicry in Neuroinflammation: Retrotransposons, cGAS-STING and Microglial Hysteresis.

Tudorache SI and 7 others. Med Sci (Basel), 2026.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Epigenetic Viral Mimicry in Neuroinflammation: Retrotransposons, cGAS-STING and Microglial Hysteresis. Papers, record 42930554. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/42930554

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Paper

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Title: Epigenetic Viral Mimicry in Neuroinflammation: Retrotransposons, cGAS-STING and Microglial Hysteresis.
Journal: Med Sci (Basel)
Year: 2026
Publication types: Journal Article, Review
PubMed: https://pubmed.ncbi.nlm.nih.gov/42930554/
DOI: https://doi.org/10.3390/medsci14060635
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC13706720/
The journal: https://conductscience.org/library/journal-index/101629322
Revised in PubMed: 2026-10-28

Source PubMed

Authors8

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	ORCID iD
1	Tudorache SI	Sorin Ioan	https://orcid.org/0000-0003-2293-6013
2	Grigorean VT	Valentin Titus
3	Dumitru AV	Adrian Vasile
4	Fulina M	Maria	https://orcid.org/0009-0003-1992-1766
5	Șerban M	Matei
6	Covache-Busuioc RA	Răzvan-Adrian
7	Toader C	Corneliu
8	Dumitrescu D	Dan	https://orcid.org/0000-0001-8413-0977

Source PubMed

Topics13

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Microglia	Major topic
Retroelements	Major topic
Epigenesis, Genetic	Major topic
Molecular Mimicry	Major topic
Nucleotidyltransferases	Major topic
Neuroinflammatory Diseases	Major topic
Membrane Proteins	Major topic
Humans
cGAS-STING Signaling Pathway
Animals
Cyclic Guanosine Monophosphate-Adenosine Monophosphate Synthase
STING Protein
Immunity, Innate

Source PubMed

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Comments and corrections0

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References245

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	38,418,882	The CRL5-SPSB3 ubiquitin ligase targets nuclear cGAS for degradation.	Nature	2024	https://conductscience.org/library/papers/38418882	PubMed
2	41,810,326	Subregional differences in the hippocampal transcriptomic response after penetrating traumatic brain injury in rats.	Front Neurol	2025	https://conductscience.org/library/papers/41810326	PubMed
3	38,096,902	Structures, functions and adaptations of the human LINE-1 ORF2 protein.	Nature	2024	https://conductscience.org/library/papers/38096902	PubMed
4	35,922,514	RNA editing underlies genetic risk of common inflammatory diseases.	Nature	2022	https://conductscience.org/library/papers/35922514	PubMed
5	42,340,846	Recurrent ZC3H18 mutations stabilize oncogenic endogenous retroviral RNA.	Cell Rep	2026	https://conductscience.org/library/papers/42340846	PubMed
6	30,679,424	Diverse motif ensembles specify non-redundant DNA binding activities of AP-1 family members in macrophages.	Nat Commun	2019	https://conductscience.org/library/papers/30679424	PubMed
7	26,343,537	Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNA.	Nat Immunol	2015	https://conductscience.org/library/papers/26343537	PubMed
8	41,082,924	Host cell Z-RNAs activate ZBP1 during virus infections.	Nature	2025	https://conductscience.org/library/papers/41082924	PubMed
9	30,002,735	L1 retrotransposition in the soma: a field jumping ahead.	Mob DNA	2018	https://conductscience.org/library/papers/30002735	PubMed
10	42,642,519	cGAS-deficient mice display premature aging associated with derepression of LINE1 elements and inflammation.	Nat Aging	2026	https://conductscience.org/library/papers/42642519	PubMed

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PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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ClinicalTrials.govNo license stated
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NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
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PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

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ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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