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Paper · 42935705

Integrative genomics and experimental validation identify a mechanosensitive gene signature associated with colorectal cancer liver metastasis.

Yang T and 5 others. iScience, 2026.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Integrative genomics and experimental validation identify a mechanosensitive gene signature associated with colorectal cancer liver metastasis. Papers, record 42935705. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/42935705

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Integrative genomics and experimental validation identify a mechanosensitive gene signature associated with colorectal cancer liver metastasis.
Journal
iScience
Year
2026
Publication types
Journal Article
Revised in PubMed
2026-10-28

Source PubMed

Authors6

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Yang TTianxue
2Yuan YYe
3Li XXue
4Wang JJiaqi
5Li CChenyao
6Xu ZZiran

Source PubMed

Topics0

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None in this release.

Grants0

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None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References63

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
120,497,297Microsomal prostaglandin E synthase-1 and 5-lipoxygenase: potential drug targets in cancer.J Intern Med2010https://conductscience.org/library/papers/20497297PubMed
225,014,786The role of mechanical forces in tumor growth and therapy.Annu Rev Biomed Eng2014https://conductscience.org/library/papers/25014786PubMed
337,497,410A Prognostic Model of Angiogenesis and Neutrophil Extracellular Traps Related Genes Manipulating Tumor Microenvironment in Colon Cancer.J Cancer2023https://conductscience.org/library/papers/37497410PubMed
419,450,707Calretinin: modulator of neuronal excitability.Int J Biochem Cell Biol2009https://conductscience.org/library/papers/19450707PubMed
535,736,631Cancer treatment and survivorship statistics, 2022.CA Cancer J Clin2022https://conductscience.org/library/papers/35736631PubMed
635,297,817Serum Syndecan-1: A Novel Biomarker for Pancreatic Ductal Adenocarcinoma.Clin Transl Gastroenterol2022https://conductscience.org/library/papers/35297817PubMed
736,219,734Alterations of the Extracellular Matrix in Colorectal Carcinoma.Genet Test Mol Biomarkers2022https://conductscience.org/library/papers/36219734PubMed
819,931,152Matrix crosslinking forces tumor progression by enhancing integrin signaling.Cell2009https://conductscience.org/library/papers/19931152PubMed
925,940,704The cAMP responsive element binding protein 1 transactivates epithelial membrane protein 2, a potential tumor suppressor in the urinary bladder urothelial carcinoma.Oncotarget2015https://conductscience.org/library/papers/25940704PubMed
1019,153,673Mechanics, malignancy, and metastasis: the force journey of a tumor cell.Cancer Metastasis Rev2009https://conductscience.org/library/papers/19153673PubMed

Cited by0

The papers in our copy of PubMed whose reference list names this one, newest first.

None in this release.

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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