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Paper · 42942833

From Target Discovery to Spatial Delivery: A Translational Roadmap for Gene-Targeted Therapies in Glioma.

Cheng H and 4 others. Pharmaceutics, 2026.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. From Target Discovery to Spatial Delivery: A Translational Roadmap for Gene-Targeted Therapies in Glioma. Papers, record 42942833. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/42942833

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
From Target Discovery to Spatial Delivery: A Translational Roadmap for Gene-Targeted Therapies in Glioma.
Journal
Pharmaceutics
Year
2026
Publication types
Journal Article, Review
Revised in PubMed
2026-10-28

Source PubMed

Authors5

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Cheng HHaohttps://orcid.org/0000-0002-7292-5198
2Zhang YYingchao
3Zhu JJinbohttps://orcid.org/0000-0003-4935-825X
4Yang YYue
5Lin JJiaqi

Source PubMed

Topics0

NLM's MeSH indexing of the paper, its major topics first.

None in this release.

Grants4

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated by
82404565National Natural Science Foundation of ChinaPubMed
82601408National Natural Science Foundation of ChinaPubMed
BK20231018Natural Science Foundation of Jiangsu ProvincePubMed
2026-BS-0916Natural Science Foundation of Liaoning ProvincePubMed

Source PubMed

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References98

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
138,653,236Integrative spatial analysis reveals a multi-layered organization of glioblastoma.Cell2024https://conductscience.org/library/papers/38653236PubMed
240,451,950Intracerebroventricular bivalent CAR T cells targeting EGFR and IL-13Rα2 in recurrent glioblastoma: a phase 1 trial.Nat Med2025https://conductscience.org/library/papers/40451950PubMed
339,901,030Novel strategies to manage CAR-T cell toxicity.Nat Rev Drug Discov2025https://conductscience.org/library/papers/39901030PubMed
437,774,317RANO 2.0: Update to the Response Assessment in Neuro-Oncology Criteria for High- and Low-Grade Gliomas in Adults.J Clin Oncol2023https://conductscience.org/library/papers/37774317PubMed
536,544,023BRD8 maintains glioblastoma by epigenetic reprogramming of the p53 network.Nature2023https://conductscience.org/library/papers/36544023PubMed
638,760,427Extracellular vesicles in glioblastoma: a challenge and an opportunity.NPJ Precis Oncol2024https://conductscience.org/library/papers/38760427PubMed
739,387,386Updated EANO guideline on rational molecular testing of gliomas, glioneuronal, and neuronal tumors in adults for targeted therapy selection-Update 1.Neuro Oncol2025https://conductscience.org/library/papers/39387386PubMed
839,075,148Epigenome editing technologies for discovery and medicine.Nat Biotechnol2024https://conductscience.org/library/papers/39075148PubMed
941,747,254Glioblastoma-Secreted C1QL1 Orchestrates Tumor Microtube Expansion and Neural Synaptic Pruning to Drive Malignant Synapse Formation and Recurrence.Cancer Discov2026https://conductscience.org/library/papers/41747254PubMed
1035,864,254Intratumoral oncolytic herpes virus G47∆ for residual or recurrent glioblastoma: a phase 2 trial.Nat Med2022https://conductscience.org/library/papers/35864254PubMed

1 to 10 of 98

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Cited by0

The papers in our copy of PubMed whose reference list names this one, newest first.

None in this release.

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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