Paper · 42948680

Osteogenic-Preconditioned Dental Follicle Cell-Derived Extracellular Vesicles Attenuate Experimental Periodontitis by Modulating Macrophage Responses.

Yi G and 8 others. Int J Nanomedicine, 2026.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Osteogenic-Preconditioned Dental Follicle Cell-Derived Extracellular Vesicles Attenuate Experimental Periodontitis by Modulating Macrophage Responses. Papers, record 42948680. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/42948680

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Osteogenic-Preconditioned Dental Follicle Cell-Derived Extracellular Vesicles Attenuate Experimental Periodontitis by Modulating Macrophage Responses.
Journal: Int J Nanomedicine
Year: 2026
Publication types: Journal Article
PubMed: https://pubmed.ncbi.nlm.nih.gov/42948680/
DOI: https://doi.org/10.2147/ijn.s636512
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC13712233/
The journal: https://conductscience.org/library/journal-index/101263847
Revised in PubMed: 2026-10-29

Source PubMed

Authors9

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	ORCID iD
1	Yi G	Genzheng	https://orcid.org/0000-0002-8432-7355
2	Huang F	Feng
3	Yang H	Huixiao	https://orcid.org/0000-0002-5197-6332
4	Kuang W	Wei
5	Liao T	Ting
6	Zhong T	Ting
7	Wu H	Huilin
8	Zhang S	Siyuan
9	Zhou L	Libin

Source PubMed

Topics12

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Periodontitis	Major topic
Macrophages	Major topic
Extracellular Vesicles	Major topic
Osteogenesis	Major topic
Dental Sac	Major topic
Animals
Rats
Male
Rats, Sprague-Dawley
Phagocytosis
Cell Movement
Cells, Cultured

Source PubMed

Grants0

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None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

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None in this release.

References44

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	41,201,881	Effectiveness of two supportive periodontal care protocols and outcome predictors during periodontitis: A randomized controlled trial.	J Periodontol	2026	https://conductscience.org/library/papers/41201881	PubMed
2	23,620,822	Comparison of odontogenic differentiation of human dental follicle cells and human dental papilla cells.	PLoS One	2013	https://conductscience.org/library/papers/23620822	PubMed
3	29,610,270	Targeted Proteomics Guided by Label-free Quantitative Proteome Analysis in Saliva Reveal Transition Signatures from Health to Periodontal Disease.	Mol Cell Proteomics	2018	https://conductscience.org/library/papers/29610270	PubMed
4	39,010,825	FGF2 is secreted in extracellular vesicles from lung cells.	Am J Physiol Lung Cell Mol Physiol	2024	https://conductscience.org/library/papers/39010825	PubMed
5	25,534,621	Periodontitis: from microbial immune subversion to systemic inflammation.	Nat Rev Immunol	2015	https://conductscience.org/library/papers/25534621	PubMed
6	35,305,266	Global, regional, and national burden of periodontitis from 1990 to 2019: Results from the Global Burden of Disease study 2019.	J Periodontol	2022	https://conductscience.org/library/papers/35305266	PubMed
7	30,064,087	Calcium phosphate particles stimulate exosome secretion from phagocytes for the enhancement of drug delivery.	Colloids Surf B Biointerfaces	2018	https://conductscience.org/library/papers/30064087	PubMed
8	26,130,255	Bortezomib Inhibits Osteoclastogenesis and Porphyromonas gingivalis Lipopolysaccharide-induced Alveolar Bone Resorption.	J Dent Res	2015	https://conductscience.org/library/papers/26130255	PubMed
9	23,007,138	Comparative study of human dental follicle cell sheets and periodontal ligament cell sheets for periodontal tissue regeneration.	Cell Transplant	2013	https://conductscience.org/library/papers/23007138	PubMed
10	37,939,516	Cyclic stretch-induced exosomes from periodontal ligament cells promote osteoblasts osteogenic differentiation via the miR-181d-5p/TNF signaling pathway.	Arch Oral Biol	2024	https://conductscience.org/library/papers/37939516	PubMed

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Cited by0

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Genes0

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None in this release.

Data0

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None in this release.

Data dates

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PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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ClinicalTrials.govNo license stated
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iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

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ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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