Paper · 42967922

Single-cell profiling uncovers a rare mesenchymal-like urothelial state associated with sarcomatoid bladder cancer.

Jacobi JJ and 11 others. Cell Death Dis, 2026.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Single-cell profiling uncovers a rare mesenchymal-like urothelial state associated with sarcomatoid bladder cancer. Papers, record 42967922. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/42967922

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Single-cell profiling uncovers a rare mesenchymal-like urothelial state associated with sarcomatoid bladder cancer.
Journal: Cell Death Dis
Year: 2026
Publication types: Journal Article
PubMed: https://pubmed.ncbi.nlm.nih.gov/42967922/
DOI: https://doi.org/10.1038/s41419-026-09136-8
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC13724738/
The journal: https://conductscience.org/library/journal-index/101524092
Revised in PubMed: 2026-11-05

Source PubMed

Authors12

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	ORCID iD
1	Jacobi JJ	Justine J	https://orcid.org/0000-0002-9109-3294
2	Xu D	Dongbo
3	Wieczorek K	Kyle
4	Wang L	Li
5	Zhang Y	Yali
6	Wang J	Jianmin	https://orcid.org/0000-0001-7527-0409
7	Singh PK	Prashant K
8	Xu B	Bo
9	Yu H	Han
10	Hussein AA	Ahmed A

1 to 10 of 12Source PubMed

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Topics9

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Urinary Bladder Neoplasms	Major topic
Urothelium	Major topic
Single-Cell Analysis	Major topic
Animals
Humans
Mice
Epithelial-Mesenchymal Transition
Gene Expression Regulation, Neoplastic
Single-Cell Gene Expression Analysis

Source PubMed

Grants6

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes it	Agency	Country	NIH project	Stated by	Source
R50 CA283805	NCI NIH HHS	United States	R50CA283805	PubMed	NIH RePORTER
P30 CA016056	NCI NIH HHS	United States	P30CA016056	PubMed	NIH RePORTER
K08 CA252161	NCI NIH HHS	United States	K08CA252161	PubMed	NIH RePORTER
R01 CA308972	NCI NIH HHS	United States	R01CA308972	PubMed	NIH RePORTER
P30CA016056	U.S. Department of Health & Human Services \| NIH \| National Cancer Institute (NCI)		P30CA016056	PubMed	NIH RePORTER
K08CA252161	U.S. Department of Health & Human Services \| NIH \| National Cancer Institute (NCI)		K08CA252161	PubMed	NIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References42

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	30,643,263	Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage.	Nat Immunol	2019	https://conductscience.org/library/papers/30643263	PubMed
2	29,732,388	Systematic Review: Characteristics and Preclinical Uses of Bladder Cancer Cell Lines.	Bladder Cancer	2018	https://conductscience.org/library/papers/29732388	PubMed
3	15,840,768	Gene deletion in urothelium by specific expression of Cre recombinase.	Am J Physiol Renal Physiol	2005	https://conductscience.org/library/papers/15840768	PubMed
4	31,974,247	Single-cell transcriptional diversity is a hallmark of developmental potential.	Science	2020	https://conductscience.org/library/papers/31974247	PubMed
5	24,556,840	Molecular mechanisms of epithelial-mesenchymal transition.	Nat Rev Mol Cell Biol	2014	https://conductscience.org/library/papers/24556840	PubMed
6	30,954,476	Scrublet: Computational Identification of Cell Doublets in Single-Cell Transcriptomic Data.	Cell Syst	2019	https://conductscience.org/library/papers/30954476	PubMed
7	37,853,467	NF-κB signaling in neoplastic transition from epithelial to mesenchymal phenotype.	Cell Commun Signal	2023	https://conductscience.org/library/papers/37853467	PubMed
8	32,300,252	Guidelines and definitions for research on epithelial-mesenchymal transition.	Nat Rev Mol Cell Biol	2020	https://conductscience.org/library/papers/32300252	PubMed
9	35,469,013	Cell type and gene expression deconvolution with BayesPrism enables Bayesian integrative analysis across bulk and single-cell RNA sequencing in oncology.	Nat Cancer	2022	https://conductscience.org/library/papers/35469013	PubMed
10	31,092,844	Enhanced metastatic potential in the MB49 urothelial carcinoma model.	Sci Rep	2019	https://conductscience.org/library/papers/31092844	PubMed

1 to 10 of 42

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Cited by0

The papers in our copy of PubMed whose reference list names this one, newest first.

None in this release.

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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