Paper · 42983029

Atf3 Regulates Spermatogenesis by Mediating Ferroptosis During Testicular Heat Exposure.

Wang C and 10 others. Reprod Sci, 2026.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Atf3 Regulates Spermatogenesis by Mediating Ferroptosis During Testicular Heat Exposure. Papers, record 42983029. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/42983029

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Paper

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Title: Atf3 Regulates Spermatogenesis by Mediating Ferroptosis During Testicular Heat Exposure.
Journal: Reprod Sci
Year: 2026
Publication types: Journal Article
PubMed: https://pubmed.ncbi.nlm.nih.gov/42983029/
DOI: https://doi.org/10.1007/s43032-026-02257-7
The journal: https://conductscience.org/library/journal-index/101291249
Revised in PubMed: 2026-11-04

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Authors11

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Wang C	Chen
2	Li X	Xin
3	Yang X	Xinyu
4	Xu S	Shumin
5	Sun B	Bingyan
6	Zhu Q	Qinran
7	An C	Chuangchuang
8	Pei Z	Zhihan
9	Liu L	Lei
10	Hua M	Mengqing

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Topics0

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Grants4

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Grant, as the record writes it	Agency	Stated by
2025AHGXZK31588	the Key Project of Natural Science Foundation of Anhui Provincial University of China	PubMed
2024AH051251	the Key Project of Natural Science Foundation of Anhui Provincial University of China	PubMed
MBZZ202402	the Open Project of Anhui Province Key Laboratory of Immunology in Chronic Diseases of China	PubMed
2023dshwyx023	the Graduate Tutor Overseas Training of Graduate Education Project for Anhui Province of China	PubMed

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Trials0

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None in this release.

Comments and corrections0

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References42

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	36,140,814	Effects of Heat Stress on Motion Characteristics and Metabolomic Profiles of Boar Spermatozoa.	Genes (Basel)	2022	https://conductscience.org/library/papers/36140814	PubMed
2	35,003,670	Plastic responses of survival and fertility following heat stress in pupal and adult Drosophila virilis.	Ecol Evol	2021	https://conductscience.org/library/papers/35003670	PubMed
3	34,758,869	Polyamine metabolism links gut microbiota and testicular dysfunction.	Microbiome	2021	https://conductscience.org/library/papers/34758869	PubMed
4	37,052,180	A starch- and ROS-regulating heat shock protein helps maintain male fertility in heat-stressed rice plants.	Plant Physiol	2023	https://conductscience.org/library/papers/37052180	PubMed
5	33,863,431	Climate change and heat stress: Impact on production, reproduction and growth performance of poultry and its mitigation using genetic strategies.	J Therm Biol	2021	https://conductscience.org/library/papers/33863431	PubMed
6	35,614,303	Effect of heat exposure on the growth and developmental competence of bovine oocytes derived from early antral follicles.	Sci Rep	2022	https://conductscience.org/library/papers/35614303	PubMed
7	36,430,241	Heat Shock Transcription Factor 2 Is Significantly Involved in Neurodegenerative Diseases, Inflammatory Bowel Disease, Cancer, Male Infertility, and Fetal Alcohol Spectrum Disorder: The Novel Mechanisms of Several Severe Diseases.	Int J Mol Sci	2022	https://conductscience.org/library/papers/36430241	PubMed
8	31,697,875	Involvement of lncRNA-HOTTIP in the Repair of Ultraviolet Light-Induced DNA Damage in Spermatogenic Cells.	Mol Cells	2019	https://conductscience.org/library/papers/31697875	PubMed
9	33,025,116	Heat stress and poultry production: impact and amelioration.	Int J Biometeorol	2021	https://conductscience.org/library/papers/33025116	PubMed
10	33,418,161	Prolonged melatonin treatment promote testicular recovery by enhancing RAC1-mediated apoptotic cell clearance and cell junction-dependent spermatogensis after heat stress.	Theriogenology	2021	https://conductscience.org/library/papers/33418161	PubMed

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Cited by0

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Genes0

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None in this release.

Drugs0

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None in this release.

Data0

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None in this release.

Data dates

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PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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