Paper · 42983086

A spatiotemporal cancer cell trajectory underlies glioblastoma heterogeneity.

de Jong G and 62 others. Nature, 2026.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. A spatiotemporal cancer cell trajectory underlies glioblastoma heterogeneity. Papers, record 42983086. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/42983086

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Paper

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Title: A spatiotemporal cancer cell trajectory underlies glioblastoma heterogeneity.
Journal: Nature
Year: 2026
Publication types: Journal Article
PubMed: https://pubmed.ncbi.nlm.nih.gov/42983086/
DOI: https://doi.org/10.1038/s41586-026-11234-8
The journal: https://conductscience.org/library/journal-index/0410462
Revised in PubMed: 2026-11-04

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Authors63

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	ORCID iD
1	de Jong G	Grant	https://orcid.org/0000-0002-5614-9651
2	Memi F	Fani
3	Gracia T	Tannia	https://orcid.org/0000-0002-8237-1870
4	Lazareva O	Olga
5	Gould O	Oliver	https://orcid.org/0009-0009-9374-4511
6	Solomou G	Georgios
7	Aivazidis A	Alexander
8	Dave M	Manas	https://orcid.org/0000-0002-1676-801X
9	Zhang Q	Qianqian
10	Jensen M	Melanie

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References70

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	20,129,251	Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1.	Cancer Cell	2010	https://conductscience.org/library/papers/20129251	PubMed
2	31,327,527	An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma.	Cell	2019	https://conductscience.org/library/papers/31327527	PubMed
3	31,901,251	Outer Radial Glia-like Cancer Stem Cells Contribute to Heterogeneity of Glioblastoma.	Cell Stem Cell	2020	https://conductscience.org/library/papers/31901251	PubMed
4	35,122,077	Gradient of Developmental and Injury Response transcriptional states defines functional vulnerabilities underpinning glioblastoma heterogeneity.	Nat Cancer	2021	https://conductscience.org/library/papers/35122077	PubMed
5	38,242,087	Glioblastoma evolution and heterogeneity from a 3D whole-tumor perspective.	Cell	2024	https://conductscience.org/library/papers/38242087	PubMed
6	35,914,528	Glioblastoma hijacks neuronal mechanisms for brain invasion.	Cell	2022	https://conductscience.org/library/papers/35914528	PubMed
7	23,412,337	Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics.	Proc Natl Acad Sci U S A	2013	https://conductscience.org/library/papers/23412337	PubMed
8	34,087,162	Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma.	Cancer Cell	2021	https://conductscience.org/library/papers/34087162	PubMed
9	35,700,707	Spatially resolved multi-omics deciphers bidirectional tumor-host interdependence in glioblastoma.	Cancer Cell	2022	https://conductscience.org/library/papers/35700707	PubMed
10	39,160,302	WebAtlas pipeline for integrated single-cell and spatial transcriptomic data.	Nat Methods	2025	https://conductscience.org/library/papers/39160302	PubMed

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Cited by0

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PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

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ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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