Paper · 4342111

The effect of ascorbic acid on collagen polypeptide synthesis and proline hydroxylation during the growth of cultured fibroblasts.

Peterkofsky B. Arch Biochem Biophys, 1972. Cited by 400 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. The effect of ascorbic acid on collagen polypeptide synthesis and proline hydroxylation during the growth of cultured fibroblasts. Papers, record 4342111. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/4342111

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: The effect of ascorbic acid on collagen polypeptide synthesis and proline hydroxylation during the growth of cultured fibroblasts.; PubMed
Journal: Arch Biochem Biophys; PubMed
Year: 1972; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/4342111/; PubMed
DOI: https://doi.org/10.1016/0003-9861(72)90221-4; PubMed
The journal: https://conductscience.org/library/journal-index/0372430; PubMed
Citations, by iCite: 400; iCite
Relative citation ratio, by iCite: 12.3; iCite
Revised in PubMed: 2019-12-10; PubMed

Authors1

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Peterkofsky B	B

Source PubMed

Topics15

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Ascorbic Acid	Major topic
Collagen	Major topic
Fibroblasts	Major topic
Proline	Major topic
Animals
Carbon Isotopes
Cell Line
Drug Stability
Hydroxylation
Hydroxyproline
Kinetics
L Cells
Mice
Microbial Collagenase
Protein Biosynthesis

Source PubMed

Grants0

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None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by88

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 400 citations.

PMID	Title	Journal	Year	In Papers	Source
32,478,965	Reducing Agent-Mediated Nonenzymatic Conversion of 2-Oxoglutarate to Succinate: Implications for Oxygenase Assays.	Chembiochem	2020	https://conductscience.org/library/papers/32478965	PubMed
32,015,161	DPP4 Inhibition, NPY1-36, PYY1-36, SDF-1α, and a Hypertensive Genetic Background Conspire to Augment Cell Proliferation and Collagen Production: Effects That Are Abolished by Low Concentrations of 2-Methoxyestradiol.	J Pharmacol Exp Ther	2020	https://conductscience.org/library/papers/32015161	PubMed
31,696,691	Bovine pericardium membrane, gingival stem cells, and ascorbic acid: a novel team in regenerative medicine.	Eur J Histochem	2019	https://conductscience.org/library/papers/31696691	PubMed
29,625,581	Evaluation of the effects of ascorbic acid on metabolism of human mesenchymal stem cells.	Stem Cell Res Ther	2018	https://conductscience.org/library/papers/29625581	PubMed
28,404,942	A novel bioactive osteogenesis scaffold delivers ascorbic acid, β-glycerophosphate, and dexamethasone in vivo to promote bone regeneration.	Oncotarget	2017	https://conductscience.org/library/papers/28404942	PubMed
28,335,738	Genome-wide expression profiling establishes novel modulatory roles of vitamin C in THP-1 human monocytic cell line.	BMC Genomics	2017	https://conductscience.org/library/papers/28335738	PubMed
27,101,406	Mechanical Strain Causes Adaptive Change in Bronchial Fibroblasts Enhancing Profibrotic and Inflammatory Responses.	PLoS One	2016	https://conductscience.org/library/papers/27101406	PubMed
26,330,548	A Novel Fully Humanized 3D Skin Equivalent to Model Early Melanoma Invasion.	Mol Cancer Ther	2015	https://conductscience.org/library/papers/26330548	PubMed
26,290,474	Vitamin C promotes wound healing through novel pleiotropic mechanisms.	Int Wound J	2016	https://conductscience.org/library/papers/26290474	PubMed
24,320,793	Construction of tissue-engineered small-diameter vascular grafts in fibrin scaffolds in 30 days.	Tissue Eng Part A	2014	https://conductscience.org/library/papers/24320793	PubMed

1 to 10 of 88

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Genes0

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None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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