ConductScience.org, home
Papers
API referenceFor AI assistants

Paper · 4359489

Phosphorylation of 5-bromodeoxycytidine in cells infected with herpes simplex virus.

Cooper GM. Proc Natl Acad Sci U S A, 1973. Cited by 65 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

Download JSON
Cite this record

ConductScience Library. Phosphorylation of 5-bromodeoxycytidine in cells infected with herpes simplex virus. Papers, record 4359489. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/4359489

On this page

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Phosphorylation of 5-bromodeoxycytidine in cells infected with herpes simplex virus.
PubMed
Journal
Proc Natl Acad Sci U S A
PubMed
Year
1973
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
65
iCite
Relative citation ratio, by iCite
1.82
iCite
Revised in PubMed
2019-12-10
PubMed

Authors1

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Cooper GMG M

Source PubMed

Topics26

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
DeoxyribonucleosidesMajor topic
DeoxyribonucleotidesMajor topic
SimplexvirusMajor topic
Adult
Animals
Bromides
Bromodeoxyuridine
Carcinoma
Carcinoma, Squamous Cell
Cell Line
Cell Transformation, Neoplastic
Cricetinae
DNA
DNA, Neoplasm
Deoxycytidine
Deoxycytidine Monophosphate
Female
Humans
Kidney
Laryngeal Neoplasms
Middle Aged
Phosphorus
Phosphotransferases
Tritium
Uterine Cervical Neoplasms
Viral Plaque Assay

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References27

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
14,284,715Properties of deoxythymidine kinase partially purified from animal tumors.J Biol Chem1965https://conductscience.org/library/papers/4284715PubMed
25,216,626In vivo studies with antiviral agents.Ann N Y Acad Sci1965https://conductscience.org/library/papers/5216626PubMed
35,323,379Clinical experience with nucleosides in herpes simplex eye infections in man and animals.Ann N Y Acad Sci1965https://conductscience.org/library/papers/5323379PubMed
44,285,582Development of resistance to antiviral drugs.Ann N Y Acad Sci1965https://conductscience.org/library/papers/4285582PubMed
54,956,026Studies of the enzymatic deamination of cytosine arabinoside. I. Enzyme distribution and species specificity.Biochem Pharmacol1965https://conductscience.org/library/papers/4956026PubMed
64,161,091Cytology and histopathology of cervical herpes simplex infection.Cancer1966https://conductscience.org/library/papers/4161091PubMed
74,289,344A virus-specific thymidine kinase in BHK-21 cells infected with herpes simplex virus.Virology1967https://conductscience.org/library/papers/4289344PubMed
85,684,726Mammalian deoxynucleoside kinase. I. Deoxycytidine kinase: purification, properties, and kinetic studies with cytosine arabinoside.J Biol Chem1968https://conductscience.org/library/papers/5684726PubMed
94,972,143Studies of the enzymatic deamination of ara-cytidine. V. inhibition in vitro and in vivo by tetrahydrouridine and other reduced pyrimidine nucleosides.Biochem Pharmacol1968https://conductscience.org/library/papers/4972143PubMed
104,315,978Evidence for the induction of a new deoxycytidine kinase in cells infected with herpes virus.Biochem J1970https://conductscience.org/library/papers/4315978PubMed

1 to 10 of 27

See all 27 references

Cited by19

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 65 citations.

PMIDTitleJournalYearIn PapersSource
15,825,318Effect of adenosine deaminase upon the antiviral activity in vitro of adenine arabinoside for vaccinia virus.Antimicrob Agents Chemother1974https://conductscience.org/library/papers/15825318PubMed
8,551,594Reactivation of thymidine kinase-defective herpes simplex virus is enhanced by nucleoside.J Virol1996https://conductscience.org/library/papers/8551594PubMed
6,303,214Incorporation of 5-substituted analogs of deoxycytidine into DNA of herpes simplex virus-infected or - transformed cells without deamination to the thymidine analog.Antimicrob Agents Chemother1983https://conductscience.org/library/papers/6303214PubMed
6,291,452Capacity of deoxycytidine to selectively antagonize cytotoxicity of 5-halogenated analogs of deoxycytidine without loss of antiherpetic activity.Antimicrob Agents Chemother1982https://conductscience.org/library/papers/6291452PubMed
6,289,324Construction of poxviruses as cloning vectors: insertion of the thymidine kinase gene from herpes simplex virus into the DNA of infectious vaccinia virus.Proc Natl Acad Sci U S A1982https://conductscience.org/library/papers/6289324PubMed
6,262,539Tetrahydrouridine specifically facilitates deoxycytidine incorporation into herpes simplex virus DNA.J Virol1981https://conductscience.org/library/papers/6262539PubMed
6,258,155Expression of the herpes thymidine kinase gene in Xenopus laevis oocytes: an assay for the study of deletion mutants constructed in vitro.Nucleic Acids Res1980https://conductscience.org/library/papers/6258155PubMed
6,254,055Nucleosomal packaging of the thymidine kinase gene of herpes simplex virus transferred into mouse cells: an actively expressed single-copy gene.Proc Natl Acad Sci U S A1980https://conductscience.org/library/papers/6254055PubMed
4,365,718Inhibition of herpes simplex virus type 2 replication by thymidine.J Virol1974https://conductscience.org/library/papers/4365718PubMed
3,010,836Plaque autoradiography assay for the detection and quantitation of thymidine kinase-deficient and thymidine kinase-altered mutants of herpes simplex virus in clinical isolates.Antimicrob Agents Chemother1985https://conductscience.org/library/papers/3010836PubMed

1 to 10 of 19

See all 19 cited by

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this paper from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/papers/v1/4359489

GET https://conductscience.org/api/papers/v1/4359489/references?page=2

API referenceFor AI assistants