ConductScience.org, home

Paper · 4401751

Definition and antagonism of histamine H 2 -receptors.

Black JW and 4 others. Nature, 1972. Cited by 2,352 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

Download JSON
Cite this record

ConductScience Library. Definition and antagonism of histamine H 2 -receptors. Papers, record 4401751. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/4401751

On this page

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Definition and antagonism of histamine H 2 -receptors.
PubMed
Journal
Nature
PubMed
Year
1972
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
2,352
iCite
Relative citation ratio, by iCite
82.6
iCite
Revised in PubMed
2019-06-17
PubMed

Authors5

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Black JWJ W
2Duncan WAW A
3Durant CJC J
4Ganellin CRC R
5Parsons EME M

Source PubMed

Topics25

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
HistamineMajor topic
Histamine H1 AntagonistsMajor topic
PyridinesMajor topic
Receptors, DrugMajor topic
ThioureaMajor topic
Animals
Benzyl Compounds
Blood Pressure
Cats
Dogs
Ethylenediamines
Female
Gastric Juice
Guinea Pigs
Heart Atria
Humans
Ileum
Imidazoles
In Vitro Techniques
Kinetics
Muscle Contraction
Muscle, Smooth
Pentagastrin
Rats
Uterus

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by555

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 2,352 citations.

PMIDTitleJournalYearIn PapersSource
42,946,944Potassium-Competitive Acid Blockers in GERD and Helicobacter pylori Infection: The Emerging Role of Fexuprazan.Drugs2026https://conductscience.org/library/papers/42946944PubMed
42,582,236Perspectives on gastric cancer: the central role of gastrin in carcinogenesis by Helicobacter pylori, oxyntic atrophy and drug-induced acid suppression.Front Oncol2026https://conductscience.org/library/papers/42582236PubMed
42,503,525The evolution of pharmacological recommendations for anaphylaxis: a comparative analysis of established textbooks.Naunyn Schmiedebergs Arch Pharmacol2026https://conductscience.org/library/papers/42503525PubMed
42,363,945Rational design of pyrazole-oxime hybrids as dual-targeting agents for glioma and breast cancer brain metastasis.Naunyn Schmiedebergs Arch Pharmacol2026https://conductscience.org/library/papers/42363945PubMed
42,238,635Histamine in Diabetic Cardiovascular Complications.Rev Cardiovasc Med2026https://conductscience.org/library/papers/42238635PubMed
41,378,221Evaluation of the clinical application of histamine H2 receptor antagonists in the prevention of chemotherapy-induced nausea and vomiting based on the attribute hierarchy model method.Front Pharmacol2025https://conductscience.org/library/papers/41378221PubMed
41,266,882Microbial Diversity Affects the Cold Tolerance of Red Swamp Crayfish (Procambarus clarkii) by Regulating Histamine Metabolism.Microb Ecol2025https://conductscience.org/library/papers/41266882PubMed
40,983,503Gastrin-dependent expansion of Cck2r+ corpus progenitors accelerates ulcer healing and inhibits gastric dysplasia.Gut2026https://conductscience.org/library/papers/40983503PubMed
40,980,118Gastrointestinal functional disorders can benefit from the use of medical devices made of substances.Front Drug Saf Regul2023https://conductscience.org/library/papers/40980118PubMed
40,502,678[History and Pharmacological Mechanism of Gastric Acid-suppressive Drugs].Korean J Helicobacter Up Gastrointest Res2023https://conductscience.org/library/papers/40502678PubMed

1 to 10 of 555

See all 555 cited by

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this paper from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/papers/v1/4401751

GET https://conductscience.org/api/papers/v1/4401751/cited_by?page=2