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Paper4402006

6 -amidinopenicillanic acids--a new group of antibiotics.

Lund F and 1 other. Nat New Biol, 1972. Cited by 200 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. 6 -amidinopenicillanic acids--a new group of antibiotics. Papers, record 4402006. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/4402006

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
6 -amidinopenicillanic acids--a new group of antibiotics.
PubMed
Journal
Nat New Biol
PubMed
Year
1972
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
200
iCite
Relative citation ratio, by iCite
6.82
iCite
Revised in PubMed
2022-03-17
PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Lund FF
2Tybring LL

Source PubMed

Topics16

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
BacteriaMajor topic
EnterobacteriaceaeMajor topic
PenicillinsMajor topic
ThiazolesMajor topic
Ampicillin
Bacillus subtilis
Bordetella pertussis
Chromobacterium
Haemophilus influenzae
Microbial Sensitivity Tests
Neisseria gonorrhoeae
Penicillanic Acid
Penicillin G
Staphylococcus
Streptococcus
Streptococcus pneumoniae

Source PubMed

Cited by83

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 200 citations.

PMIDTitleJournalYearIn PapersSource
38,686,211A large screen identifies beta-lactam antibiotics which can be repurposed to target the syphilis agent.NPJ Antimicrob Resist2023https://conductscience.org/library/papers/38686211PubMed
37,660,037Pivmecillinam with Amoxicillin/Clavulanic acid as step down oral therapy in febrile Urinary Tract Infections caused by ESBL-producing Enterobacterales (PACUTI).Trials2023https://conductscience.org/library/papers/37660037PubMed
35,719,201In vitro activity of mecillinam, temocillin and nitroxoline against MDR Enterobacterales.JAC Antimicrob Resist2022https://conductscience.org/library/papers/35719201PubMed
35,590,284The efficacy of pivmecillinam in oral step-down treatment in hospitalised patients with E. coli bacteremic urinary tract infection; a single-arm, uncontrolled treatment study.BMC Infect Dis2022https://conductscience.org/library/papers/35590284PubMed
35,115,684Cell density-dependent antibiotic tolerance to inhibition of the elongation machinery requires fully functional PBP1B.Commun Biol2022https://conductscience.org/library/papers/35115684PubMed
33,510,739Susceptibility of Clinical Enterobacterales Isolates With Common and Rare Carbapenemases to Mecillinam.Front Microbiol2020https://conductscience.org/library/papers/33510739PubMed
31,332,059Upregulation of PBP1B and LpoB in cysB Mutants Confers Mecillinam (Amdinocillin) Resistance in Escherichia coli.Antimicrob Agents Chemother2019https://conductscience.org/library/papers/31332059PubMed
31,067,667Pivmecillinam for Uncomplicated Lower Urinary Tract Infections Caused by Staphylococcus saprophyticus-Cumulative Observational Data from Four Recent Clinical Studies.Antibiotics (Basel)2019https://conductscience.org/library/papers/31067667PubMed
30,917,983Results from a Prospective In Vitro Study on the Mecillinam (Amdinocillin) Susceptibility of Enterobacterales.Antimicrob Agents Chemother2019https://conductscience.org/library/papers/30917983PubMed
29,872,326Mecillinam for the treatment of acute pyelonephritis and bacteremia caused by Enterobacteriaceae: a literature review.Infect Drug Resist2018https://conductscience.org/library/papers/29872326PubMed
28,864,161Mecillinam - Reversion of Resistance and How to Test It.EBioMedicine2017https://conductscience.org/library/papers/28864161PubMed
28,855,073Reversion of High-level Mecillinam Resistance to Susceptibility in Escherichia coli During Growth in Urine.EBioMedicine2017https://conductscience.org/library/papers/28855073PubMed
27,126,213Classic Spotlight: Staying in Shape and Discovery of the mrdAB and mreBCD Operons.J Bacteriol2016https://conductscience.org/library/papers/27126213PubMed
25,583,718Amdinocillin (Mecillinam) resistance mutations in clinical isolates and laboratory-selected mutants of Escherichia coli.Antimicrob Agents Chemother2015https://conductscience.org/library/papers/25583718PubMed
24,272,507The molecular basis for the mode of action of Beta-lactam antibiotics and mechanisms of resistance.Pharm Res1985https://conductscience.org/library/papers/24272507PubMed
24,036,533Genome signature-based dissection of human gut metagenomes to extract subliminal viral sequences.Nat Commun2013https://conductscience.org/library/papers/24036533PubMed
22,216,505Factors influencing the absorption and disposition of mecillinam and pivmecillinam in man.Br J Clin Pharmacol1976https://conductscience.org/library/papers/22216505PubMed
17,725,227Of the morphogenes that make a ring, a rod and a sphere in Escherichia coli.Sci Prog2007https://conductscience.org/library/papers/17725227PubMed
8,682,786Mecillinam resistance in Escherichia coli is conferred by loss of a second activity of the AroK protein.J Bacteriol1996https://conductscience.org/library/papers/8682786PubMed
8,407,846Penicillin-binding protein 2 inactivation in Escherichia coli results in cell division inhibition, which is relieved by FtsZ overexpression.J Bacteriol1993https://conductscience.org/library/papers/8407846PubMed

See all 83 cited by

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Grants
  • Trials
  • Comments and corrections
  • References
  • Genes
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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