Paper · 4459

L-Asparaginase of Klebsiella aerogenes. Activation of its synthesis by glutamine synthetase.

Resnick AD and 1 other. J Biol Chem, 1976. Cited by 30 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. L-Asparaginase of Klebsiella aerogenes. Activation of its synthesis by glutamine synthetase. Papers, record 4459. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/4459

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: L-Asparaginase of Klebsiella aerogenes. Activation of its synthesis by glutamine synthetase.; PubMed
Journal: J Biol Chem; PubMed
Year: 1976; PubMed
Publication types: Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, U.S. Gov't, P.H.S.; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/4459/; PubMed
The journal: https://conductscience.org/library/journal-index/2985121R; PubMed
Citations, by iCite: 30; iCite
Relative citation ratio, by iCite: 1.24; iCite
Revised in PubMed: 2021-02-10; PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Resnick AD	A D
2	Magasanik B	B

Source PubMed

Topics15

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Asparaginase	Major topic
Glutamate-Ammonia Ligase	Major topic
Klebsiella	Major topic
Alkaline Phosphatase
Cell Division
Enzyme Activation
Galactosidases
Genotype
Histidine Ammonia-Lyase
Hydrogen-Ion Concentration
Kinetics
Muramidase
Mutation
Phenotype
Species Specificity

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by18

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 30 citations.

PMID	Title	Journal	Year	In Papers	Source
16,662,109	Regulation of asparaginase, glutamine synthetase, and glutamate dehydrogenase in response to medium nitrogen concentrations in a euryhaline chlamydomonas species.	Plant Physiol	1981	https://conductscience.org/library/papers/16662109	PubMed
16,578,813	The actinorhizal root-nodule symbiont Frankia sp. strain CpI1 has two glutamine synthetases.	Proc Natl Acad Sci U S A	1987	https://conductscience.org/library/papers/16578813	PubMed
11,673,431	Roles of glutamate synthase, gltBD, and gltF in nitrogen metabolism of Escherichia coli and Klebsiella aerogenes.	J Bacteriol	2001	https://conductscience.org/library/papers/11673431	PubMed
7,240,099	Regulation of L-asparaginase in a Chlamydomonas species in response to ambient concentrations of combined nitrogen.	J Bacteriol	1981	https://conductscience.org/library/papers/7240099	PubMed
6,896,642	Isolation and characterization of a Chlamydomonas L-asparaginase.	Biochem J	1982	https://conductscience.org/library/papers/6896642	PubMed
6,783,624	Serine utilization by Klebsiella aerogenes.	J Bacteriol	1981	https://conductscience.org/library/papers/6783624	PubMed
6,129,565	A nonsense mutation in the structural gene for glutamine synthetase leading to loss of nitrogen regulation in Klebsiella aerogenes.	Mol Gen Genet	1982	https://conductscience.org/library/papers/6129565	PubMed
6,125,499	Asparagine synthetases of Klebsiella aerogenes: properties and regulation of synthesis.	J Bacteriol	1982	https://conductscience.org/library/papers/6125499	PubMed
6,109,705	Tryptophan metabolism in Klebsiella aerogenes: regulation of the utilization of aromatic amino acids as sources of nitrogen.	J Bacteriol	1981	https://conductscience.org/library/papers/6109705	PubMed
6,102,851	The enzymes of the ammonia assimilation in Pseudomonas aeruginosa.	Arch Microbiol	1980	https://conductscience.org/library/papers/6102851	PubMed

1 to 10 of 18

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Genes2

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes	Source
GLUL	2,752	PubTator's text mining	https://conductscience.org/library/genes/2752	NCBI Gene
HAL	3,034	PubTator's text mining	https://conductscience.org/library/genes/3034	NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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